XL20.XL9 Tube Handler

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Tube Handler for sorting, cherry-picking, rearraying, decoding, and weighing tubes from Matrix, Micronic, ABgene, and Corning.

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XL20.XL9 Tube Handler

  1. 1. BioMicroLab Sample Management AutomationTube and Vial Handling SampleScan 2D Volume barcode readers Verification
  2. 2. About BioMicroLab BioMicroLab’s parent company: CopyPro, Inc.  20-year track record in manufacturing material handling products  Modern CNC sheet metal/machined metal production systems  In-house engineering team  Focus: Industrial products with easy-to-use software  Holds several US Patents BioMicroLab’s history  2001 - XL20 Tube Handling Instrument development begins  2003 - BioMicroLab incorporates  2004 - XL20 launched at Lab Automation Conference  2004 - Released 2D tube rack and single tube readers  2005 - XL9 Tube Handler introduced  2006 - Launched SampleScan HS and VolumeCheck at Lab Automation 2006  2007 – Shipped 100th XL20 Tube Handling System  2008 – Released XL100 Vial Handling Instrument  2009 – Introduced the SampleScan Mini and SampleScan Plus  2010 – Released Decapper and Automated Capper for XL100  2011 – Added Liquid Handling to the XL100
  3. 3. Typical BioMicroLab Customers• Compound Sample Management Laboratory – Large Pharmaceutical Companies • Bench top automation for central sample repositories – Small and Large Biotech Companies • Main robot for handling laboratory sample libraries• Genomic Research Facilities – Usually research departments at Hospitals and Universities • Genomic Core Facilities • Tissue Banks • DNA Banks • BioBanks
  4. 4. BioMicroLab Customers
  5. 5. Sample Management Automation Tube Handling Instruments – XL20 Tube Handling Instrument – XL9 Tube Handling Instrument – XL100 Vial Handling Instrument – MX4 Sort and Scan SampleScan 2D Readers – SampleScan 96 – multi-rack reader – SampleScan Plus – single tube reader – SampleScan HS – camera based high speed reader – SampleScan Mini – scanner based high speed reader Volume Verification Instruments – VolumeCheck – ultrasonic detection of sample in well plates – XL20 Automated Balance – gravimetric volume tracking – XL20 LevelCheck – sensor detects sample meniscus in capped vials
  6. 6. BioMicroLab Tube Handlers XL20 Tube Handler XL100 Vial Handler XL9 Tube Handler MX4 Sort and Scan
  7. 7. VolumeCheckVolumeCheck – Volume Verification Instrument
  8. 8. SampleScan 2D Barcode Readers SampleScan Mini SampleScan Mini with1D reader Single Rack Reader Fully Automated Single Rack ReaderSampleScan HS Single RackHigh Throughput SampleScan 96 Entry-Level SampleScan Plus Single Rack Scanner Single Tube Reader
  9. 9. XL20 Tube Handling InstrumentXL20 Tube Handling Instrument XL9 Tube Handling Instrument
  10. 10. XL20 Tube Handler Applications  Key XL20 applications  Automated analytical balance used to confirm sample volume  Automated tube sorter to manage handling of sample libraries  Typical applications  Cherry Picking tubes  Re-arraying sample libraries  Handling samples from combinational chemistry labs  Weighing tubes to calculate sample volume  LevelCheck tubes for fast volume data return
  11. 11. Workflow Application
  12. 12. XL20 Features & Benefits Features Benefits- Small bench top robot for 96 tube - Saves time and resourcessample format- Processes 0.3 ml to 1.4 ml tubes - Extend laboratory’s samplefrom Micronic, ABgene, Corning, & tracking capabilitiesMATRIX- Automates tube sorting, 2D - Leverages laboratory’s investmentscanning, and weighing in 2D tube storage systems- Faster & less costly thancompeting automated balances - Ease-of-use allows operation by a- Quick integration & deployment wide variety of users(operational the day of installation)
  13. 13. XL20 Hardware OptionsXL20 Instrument Options  2D barcode reader module  Integrated single tube reader  Decodes 2D marked tubes while sorting  Analytical Balance module  captures tube weight  0.0001g readability  Software application specific to net weight capture of tube sample  LevelCheck module  Non-contact sensor detects sample meniscus and returns volume data
  14. 14. 2D Camera Option2D Camera Module  Scans and decodes 2D barcoded vials  Captures 2D barcode while processing tubes  Module does not use tube rack nest
  15. 15. Analytical Balance OptionAnalytical Balance  Weighing range 60g  Readability at the interface 0.0001g  Reproducibility = +/- 0.0001g  Linearity <= +/- .0002g  Response time average <= 2 sec
  16. 16. LevelCheck Option LevelCheck Module for XL20/XL9  Non-Contact sample volume detection  Accuracy: +/- 10 – 15uL  Collects volume data while sorting, rearraying, and capturing 2D barcodes  LevelCheck one rack in about 15 minutes  Sample image and capture recall – store tube images with 2D barcode data  XL20 systems can be field upgraded with the LevelCheck system No loss of sorting positions LevelCheck uses tube rack position when scale is present #5 on XL20 sorting platform
  17. 17. XL9 Tube Handling InstrumentXL20 & XL9 robotics are identical  XL20 has 28.5” width and 20 rack positions  XL9 has 18” width and 9 rack positions
  18. 18. Workflow with BioMicroLab software Work List Mode 5. Import file for 1. Query for sample list LIMS database update LIMS (database) 2. Create XL20 input Output Input format (.csv) .csv .csv 4. XL20 creates output file for each rack (.csv) 3. XL20 imports and XL20 sorts tubes
  19. 19. Workflow with ActiveX software Query for sample list LIMS (database) XL20 XL20 sorts/weighs tubes Sorting data automatically updates LIMSNote: ActiveX requires customer IT group provide database integration software support.
  20. 20. XL20 Work List Manager Software
  21. 21. XL Tube Handler Processing ModesTube Handler modes of operation• Work List Based – rearray applications 1. Sequential • Racks are processed in work list order only 2. Random • Racks are processed in random order• No Work List Required – pick and place vial from same location 1. Tare/Gross Weigh • Tare and gross weight of vials • Streamlined weighing mode 2. Data Collection Mode • Typically used to collect linear barcodes or vial weight with XL100
  22. 22. XL20 Tube Handler Input Work ListWork list example  Source Rack ID  Source Tube Location  Expected Tube 2D bar code (optional)  Target Rack ID  Target Tube Location
  23. 23. XL20 Tube Handler Software FeaturesMain Processing Screen – Work list controlled movement of tubes – Confirms tube ID from work list with captured 2D data – Captures image of 2D barcode for error handling – Sample weight capture displayed Click to import work list – Software generates Job ID for tracking in your LIMS system – Start, Stop, and Pause
  24. 24. Input File SettingsInput Files Settings  Provides flexibility for importing work lists with header files or extra characters
  25. 25. XL20 Tube Handler Tray SetupWork List Software – Assignment of racks to XL20 platform locations – Color coded interface guides user through tube rack loading process – Supports input from hand held bar code scanner XL9 Tube Handling System displayed
  26. 26. XL20 Tube Rack Loading Process Scanning the tube rack position Scanning the barcode ID on XL20/XL9 platform label on the tube rackXL9 Tube Handling System displayed
  27. 27. XL20 Tube Handler Software Features To Start - press job initiator button Can view live video vs. captured bitmap  Barcode Read  Returns decoded barcode Status column  OK  Bar code mismatch Captures data while processing Weight column tubes  Returns weight
  28. 28. XL20 Work List Mode Output File Generates LIMS output file for use by sample tracking systems  Operator can pre-determine content of output file  Output file can be placed in folder on a network  Example of Work List Processing Mode Output
  29. 29. Example of Work List Mode Output File
  30. 30. LevelCheck OutputLevelCheck Output  Volume data output in .csv output file  Volume data associated with 2D barcode via output file  Tube images output .JPEG LevelCheck output file example LevelCheck visual inspection
  31. 31. XL20 Tube Handler Tare/Gross WeighTare Gross Weighing Mode  Data Collection mode  Interactive selection of tube positions during the weighing mode set up  Provides full flexibility for a wide variety of weighing applications
  32. 32. Tare/Gross Weigh Output File OptionsOutput File Options forTare/Gross Weigh Mode  Operator can pre-determine content of output file  Output file can be placed in folder on a network  Example of Work List Processing Mode Output
  33. 33. Example of Tare/Gross Weigh Output File
  34. 34. XL20 Tube Handler Error HandlingError handling for operations Tube Movement:  Picking Tube  Placing Tube Bar Code Decoding:  Barcode Miss-match  Decode failure Error handling features selectable by the operator Audible Alarms
  35. 35. XL20 Tube Handler Robot ControlManual control of robot vialoader control panel  Troubleshooting  Individual tube movements  Calibrate Scale  Calibrate Camera Option
  36. 36. XL20 Product Specifications Operating Requirements:  Electrical: 110-220 VAC 60Hz  Environment: Ambient Room Model: 4 C to 40 C, 10-90% RH Cold Room Model: -4 C to 40 C, 10-90% RH Machine Specifications:  Weight: XL20 : 42 lbs XL9: 22 lbs  Dimensions: XL20: 28.25" W x 21" L x 16" H XL9: 18.00” W x 17” L x 16” H
  37. 37. XL20 Product Specifications PC System Requirements:  Windows XP/Vista/7  2.2+ GHz computer processor  512MB RAM (1GB recommended)  Standard Serial and USB Ports
  38. 38. BioMicroLab Service and Support BioMicroLab Service Support Center – Concord, CA, USA Service Offering – Service Agreements – Phone – Email – Library of technical data sheets – Preventative Maintenance Service Program Onsite Support – BioMicroLab Direct – Reseller support network
  39. 39. Contact InformationBioMicroLab, Inc.Web: www.biomicrolab.comEmail: info@biomicrolab.com Tel: (925) 689-1200 or Fax: (925) 689-1263 Mail: 2500-A Dean Lesher Drive Concord, CA 94520 USA

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