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Ankylosing Spondylitis


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Brief description of Ankylosing Spondylitis. For more information go to

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Ankylosing Spondylitis

  1. 1. Ankylosing Spondylitis Presented by Christopher BeckmanProgram Director, Athletes Joined Against Spondylitis
  2. 2. Basic • A non-rheumatoid inflammatory arthritis inOverview which the joints of the spine, particularly the lower back, become inflamed and painful • Inflammation causes new bone to grow • Fuses the vertebrae together • Restricts flexibility and movement. • Ankylosis means "fusion," and spondyl means "vertebra."
  3. 3. Overview • Ankylosing spondylitis affects the sacroiliacContd joints (where the spine joins the pelvis) • Can progress to involving the joints where the ribs attach to the spine and many other organs as well
  4. 4. • Lower back and hip painSymptoms and stiffness that persists for three or more months • Pain and stiffness in morning • Gets better after exercise, worse after rest • Fatigue, fever and loss of appetite and weight
  5. 5. Symptoms • About 1 in 4 people getContd inflammation of the eye, or iritis • Swollen joints; this symptom is indistinguishable from rheumatoid arthritis
  6. 6. Demographics• Mainly afflicts men between the ages of 14 and 35
  7. 7. • There is no cureTreatment • Medication helps to relieve pain and stiffness • Surgery is sometimes done but still doesn’t cure it, it just restores movement to the joints
  8. 8. • No test to positivelyDiagnosis diagnose it • Doctor tests for spinal inflammation and the presence of HLA-B27 which are major signs of AS
  9. 9. • Typically NSAIDs (non-Medication steroidal anti-inflammatory drugs) and TNFs (Tumor Necrosis Factor) • Most effective is Indomethacin • Another drug is Sulphasalazine (Salazopyrin) • NSAIDs control disease activity • Most medications are very expensive
  10. 10. • AS can progress toComplications involve the ribs, which can make it difficult to breath • Smoking increases AS severity 400% • Works in tandem with rib fusion to severely restrict breathing which can ultimately lead to death due to lack of oxygen