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Synapic transmission

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Synapic transmission

  1. 1. Synaptic transmission By:- Atifa Ambreen Medical lab technology
  2. 2. synapse  Site of functional communication between neurons is called as Synapse.
  3. 3. Synaptic transmission  Transfer of information across synapse from presynaptic neuron to postsynaptic neuron is called synaptic transmission.
  4. 4. Mechanism  Action potential spread over presynaptic terminal Memberane  Membrane depolarization  Ca diffuses into presynaptic terminal  Ca binds at release site(specific protein molecule on the inside surface of presynaptic membrane)
  5. 5.  Synaptic vesicles bind with release site.  Neurotransmitter released into synaptic cleft by exocytosis.  Neurotransmitter binds with receptor protein on postsynaptic membrane.
  6. 6. Factors that increase synaptic transmission  Alkalosis  Caffeine  Theophyline  Theo bromine  Strychnine
  7. 7. Factors that decrease synaptic transmission  Acidosis  Hypoxia  anesthesia

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