Nutraceuticals- As a product isolated or purified from the food generally sold in medicinal form not assisted with food and demonstrated to have a physiological benefit and provide protection against chronic disease.
The concept of food as medicine is an ancient one, noticeably strengthened byreports from contemporary medical research and practice. The Greek physicianHippocrates, often known as the “father of medicine” enunciated this belief severalcenturies ago, as “let food be your medicine”. The term "Nutraceutical" was coined by combining the terms "Nutrition" and "Pharmaceutical" in 1989 by Dr Stephen DeFelice
polyphenols (hydrolyzable and condensedtannins)Green tea polyphenols, mainly catechins and epicatechins
• The Greek physician Hippocrates, often known as the
“father of medicine” said “let food be your medicine”.
The Philosophy behind is:
“Focus on Prevention”
• The term "Nutraceutical" was coined by combining the
terms "Nutrition" and "Pharmaceutical" in 1989 by
Dr. Stephen DeFelice.
to Dr. DeFelice , “Nutraceutical is any
substance that is a food or a part of food that provides
medicinal or health benefits including the prevention and
treatment of disease.”
• Health ministry of Canada defines it “As a product isolated
or purified from the food generally sold in medicinal form
not assisted with food and demonstrated to have a
physiological benefit and provide protection against
Plants or herbs particularly Fruits and
Vegetables are the cheapest and most common store
of Nutrients i.e:• Carbohydrates
• And essential amino acids
Classification of Nutraceuticals
1. Potential Nutraceuticals - one which has promising
approach towards particular health or medicinal benefit.
2. Established Nutraceuticals – A Potential Nutraceutical
becomes Established Nutraceutical only after there are
sufficient clinical data to demonstrate such a benefit.
Raaz et al. 2011.
Nutraceuticals mainly consists of :
Nutritional functions e.g. Vitamins, Minerals, Amino
Acids, Fatty acids, etc.
2. Herbals/ Phytochemicals: Herbs or Botanical products
Probiotics, Prebiotics, Antioxidents, Enzymes, etc.
Nutrients used as
• Minerals and
• or in combination of
• or in combination
Avrelija and Walter , 2010
3. Dietary supplements:
administered in adequate amounts, confer a health
benefit on the host
Species of Lactobacillus
Yeast Saccharomyces Cerevisiae
some E. Coli and Bacillus species are also used as
• Probiotics have been shown to have applications in
allergies, cancer, AIDS, respiratory and urinary tract
Nondigestible substances that provide a
beneficial physiological effect for the host by selectively
stimulating the favorable growth of a limited number of
Commonly known prebiotics are:
• Oligofructose .
Areas covered by Nutraceuticals :
All therapeutic areas such as,
Anti- Arthritic (Rheumatoid Arthritis)
Prevention of certain cancers (Colorectal cancer)
Cholesterol lowering (garlic)
Neurological disorders (Autism)
Dietary polyphenols as potential nutraceuticals in management of diabetes
by Bahadoran et al. 2013.
Mahima et al. 2013
M.Tech Seminar- I Dept. of Chemical Engg.
M.Tech Seminar- I Dept. of Chemical Engg.
Nutraceuticals may range in the form of :
• isolated nutrients,
• dietary supplements,
• genetically engineered “designer” food,
• herbal products,
• and processed products such as cereals, soups, and
Nutraceuticals may be beneficial to our health but we are still
learning about their benefits and possible harmful effects.
Government regulatory bodies also face challenges in this new
category of health products, which lies between foods and
Health professional , Nutritionists and regulatory toxicologist
regulation to provide ultimate health and therapeutic benefit to
Brower V. “Nutraceuticals: poised for a healthy slice of the healthcare market”
Nat. Biotechnol.1998, 16, 728-731.
http://www.hc-sc.gc.ca/sr-sr/biotech/about.apropor/gloss-eng.php(assessed on 23
Raaz .M; Priyanka S; Bina R; Chauhan AK. “Healthy living with Nutraceuticals”
International Research Journal of Pharmacy 2011,2(12),12-14
Bahadoran Z; Parvin M; Fereidoun A. “Dietary polyphenols as potential
Nutraceuticals in management of diabetes” Journal of Diabetes & Metabolic
Mahima ; Amit K; Ruchi T; K Karthik” Nutraceuticals from fruits and vegetables at
glance” . Journal of Biological sciences 2013,13(3):38-47
Avrelija C and Walter C “ The role of functional foods, Nutraceuticals and food
Sarin R; Sharma M; Singh R; Kumar S ” Nutraceuticals” International Research
Journal of Pharmacy 2012, 3 (4)
Prasuram RR ; Rawat B ; Thangavel S “ Nutraaceuticals : An Area of
Tremendous Scope” International Research Journal of Pharmacy 2011, 2(2) 410415