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  1. 1. <ul><li>A CASE REPORT ON AMELOBLASTOMA </li></ul>
  2. 2. INTRODUCTION <ul><li>True neoplasm of odontogenic epithelium </li></ul><ul><li>Term “ Ameloblastoma” coined by Churchill – 1934. </li></ul><ul><li>“ Unicentric, nonfunctional, intermittent in growth, anatomically benign, clinically persistent”. </li></ul><ul><li>2 nd most common odontogenic neoplasm, & represents 1% of all oral odontogenic epithelial tumors & 11% of all odontogenic tumors. </li></ul>
  4. 4. <ul><li>60 year old female </li></ul><ul><li>c/o swelling on right cheek since 2 years. </li></ul>
  5. 5. Extra orally; 1 year back
  6. 6. Swelling 1 year back Present size
  7. 7. Intra oral swelling
  8. 8. 1 year back Present oral swelling
  9. 9. <ul><li>Provisional diagnosis – </li></ul><ul><li>AMELOBLASTOMA </li></ul><ul><li>Differential diagnosis – </li></ul><ul><li>1) Odontogenic Keratocyst </li></ul><ul><li>2) Central giant cell granuloma </li></ul><ul><li>3) CEOT </li></ul><ul><li>4) Odontogenic myxoma </li></ul><ul><li>5) COC </li></ul>
  10. 10. INVESTIGATIONS <ul><li>Radiological – OPG, lateral occlusal mandibular radiograph </li></ul><ul><li>Complete blood picture, CT, BT </li></ul><ul><li>Incisional biopsy </li></ul>
  11. 11. Present radiograph 1 year back
  12. 12. Bicortical expansion
  13. 16. <ul><li>Differential diagnosis – </li></ul><ul><li>1) central giant cell granuloma </li></ul><ul><li>2) odontogenic Keratocyst </li></ul><ul><li>3) odontogenic myxoma </li></ul><ul><li>4) ossifying fibroma </li></ul>
  14. 17. central giant cell granuloma
  15. 18. Odontogenic Keratocyst Right body and ramus of the mandible
  16. 19. 03/27/10 Odontogenic myxoma
  17. 20. DISCUSSION
  18. 21. <ul><li>Etiology – </li></ul><ul><li>Varied origin </li></ul><ul><li>cell rests of enamel organ </li></ul><ul><li>Epithelium of odontogenic cysts </li></ul><ul><li>Disturbances of developing enamel organ </li></ul><ul><li>Basal cells of surface epithelium of the jaws </li></ul><ul><li>Heterotopic epithelium in other parts of the body </li></ul>
  19. 22. CLINICAL FEATURES <ul><li>Wide age range, but uncommon in children and adults < 20 yrs of age </li></ul><ul><li>Posterior mandible </li></ul><ul><li>Asymptomatic, often discovered on routine radiographs </li></ul><ul><li>As tumor grows, painless enlargement may be noted </li></ul>
  20. 23. RADIOLOGICAL FEATURES <ul><li>Unilocular radiolucency, especially early lesions that often progress to multilocular ( soap-bubble, honeycomb ) </li></ul><ul><li>May be associated with impacted tooth </li></ul><ul><li>Cortical expansion and thinning </li></ul><ul><li>Resorption of adjacent tooth roots, displacement of teeth can be seen </li></ul>