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237 vulnerable plaque in esc 2002

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237 vulnerable plaque in esc 2002

  1. 1. Editorial Slides VP Watch – September 4, 2002 - Volume 2, Issue 35 Vulnerable Plaque in ESC 2002 Berlin, Germany; August 31 – September 4, 2002
  2. 2.  In the past few days vulnerable plaque was the focus of several hot scientific sessions at the Congress of European Society of Cardiology in Berlin.
  3. 3.  Abundance of basic investigations related to underlying mechanisms involved in plaque inflammation, new markers of plaque vulnerability, along with clinical topics related to detection of vulnerable plaque particularly live case presentations of emerging diagnostic techniques such as thermography and elastography, all have made ESC2002 an important event for the rapidly growing field of vulnerable plaque.
  4. 4.  The world of cardiology is now impatiently looking forward to the results of large clinical studies in which the predictive values of the emerging diagnostic devices are evaluated.  Reproducible and validated data from such trials may provide new guidelines for risk stratification and management of patients at risk of future coronary events.
  5. 5.  Selected sessions related to VP council of biology:  Endothelial dysfunction: new targets?  Gene therapy in coronary and myoardial disease  Genetic in atherosclerosis  Modulation of atherosclerotic plaque inflammation  Molecular studies in atherosclerosis  New cardiac markers  Inflammatory injury of the vessel wall  Inflammation in atherosclerosis  Oxidation and atherosclerosis  Predictors of atherosclerosis  Genetic in atherosclerosis  Gene polymorphism in coronary artery disease  Lipids and atherosclerosis
  6. 6.  Selected sessions related to VP council of detection:  Characterization of vulnerable plaque by heat, elasticity, or morphology  Cardiac computed tomography: something new on the horizon?  Imaging the coronary artery: are the new techniques competitors are adjuncts to angiography?  New trends in imaging  Imaging of atherosclerosis  Magnetic resonance imaging: what’s new?  Lesion severity: our eyes are not good enough!
  7. 7.  Selected sessions related to VP council of treatment:  Carotid stenting  Coronary revascularization: needle or knife?  Drug eluting stents: are they still holding their promise?  Drug eluting stents: options beyond sirolimus?  Effects of new and established lipid-lowering drugs  Non-lipid-lowering effects of statins  Percutaneous coronary intervention: variations in stenting, cutting, and spotting  We are still on the way: drug eluting and coated stents  Restenosis and genetics  Growth factor and cell proliferation in atherosclerosis  Brachytherapy, coated stents
  8. 8.  Selected sessions related to VP council of pathology:  Inflammatory injury of the vessel wall  Infection in atherosclerosis  Selected sessions related to VP council of thrombosis:  Thrombosis – endothelial function  Young Investigators' Award Session (Basic Science)
  9. 9.  Selected sessions related to VP council of animal models:  Molecular mechanisms of atherosclerosis from mouse to man  Animal models in atherosclerosis  Selected sessions related to VP council of epidemiology:  Atherosclerosis and coronary heart disease  Management of patients at risk: risk stratification and treatment for the prevention of cardiovascular disease
  10. 10. Conclusion  The field of vulnerable plaque is rapidly expanding.  The underlying mechanisms of plaque vulnerability are increasingly being elucidated.  New markers of patients vulnerability are discovered.  Emerging VP detection technologies are impatiently called for clinical trials.
  11. 11. Questions: • How long from now do you expect to see the new VP detection methods widely available in cath-labs? – See VP.org Poll of the Week for more

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