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Kurdistan Board GEH/GIT Surgery J Club 2020
Supervised by Professor Dr. Mohamed Alshekhani.
The benefits of dietary fibre on GIT health demonstrated from
consumption of unrefined whole foods containing fibers, as whole
Isolated & extracted fibres have demonstrated promising regulatory
effects on the gut (for example, digestion,absorption, transit time, stool
formation) & microbial effects (changes in gut microbiota composition &
fermentation metabolites) with important implications for GIT disorders.
The physicochemical properties of different dietary fibres (solubility,
viscosity,fermentability) vary greatly depending on the origin- processing
&are important of the functional characteristics&clinical utility
Manipulating &/or increasing fibre intake is a promising therapeutic
strategy in the prevention / management of many GIT disorders.
Physicochemical characteristics; solubility, viscosity & fermentability drive
different functionalities in GIT dis underpining their therapeutic potential.
Current guidelines/recommendations reflect earlier studies using wide
range of dietary fibres with diff physicochem&functional characteristics.
The lack of consistenc& reporting of these characteristics in studies to date
has limited the clinical utility of dietary fibre for managing GIT disorders.
There is an urgent need for well- designed RCTs to determine which
physicochemical characteristics, fibre source,what doses & durations are
optimal for clinically meaningful GIT health benefits.
Co- administration of different fibres with differing physiological effects,
or novel, naturally occurring dietary fibres with dual physiological
properties has yet to be explored&holds promise as a therapeutic strategy
across several gastrointestinal disorders.