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Hyper calcaemia DR SHABEEL’S PRESENTATIONS
Causes
With normal / elevated PTH <ul><li>Primary / tertiary hyper parathyroidism  </li></ul><ul><li>Lithium induced  </li></ul><...
With low PTH <ul><li>Malignancy ( lung / breast / ovary etc ) </li></ul><ul><li>Multiple myeloma  </li></ul><ul><li>Thyrot...
Clinical features <ul><li>Polyuria / polydipsia  </li></ul><ul><li>Lethargy / anorexia / nausea  </li></ul><ul><li>Dyspeps...
Investigations  <ul><li>S.calcium – increased </li></ul><ul><li>Phosphates – decreased  </li></ul><ul><li>Alkaline phospha...
Management  <ul><li>Re-hydration with normal saline 4-6 L </li></ul><ul><li>Pamidronate  </li></ul><ul><li>Forced diuresis...
 
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Hyper Calcaemia

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Hyper Calcaemia

  1. 1. Hyper calcaemia DR SHABEEL’S PRESENTATIONS
  2. 2. Causes
  3. 3. With normal / elevated PTH <ul><li>Primary / tertiary hyper parathyroidism </li></ul><ul><li>Lithium induced </li></ul><ul><li>Familial hypocalciuric hypercalcaemia </li></ul>
  4. 4. With low PTH <ul><li>Malignancy ( lung / breast / ovary etc ) </li></ul><ul><li>Multiple myeloma </li></ul><ul><li>Thyrotoxicosis </li></ul><ul><li>Paget’s disease </li></ul><ul><li>Thiazide diuretic </li></ul><ul><li>Addison’s disease </li></ul>
  5. 5. Clinical features <ul><li>Polyuria / polydipsia </li></ul><ul><li>Lethargy / anorexia / nausea </li></ul><ul><li>Dyspepsia / peptic ulceration </li></ul><ul><li>Constipation </li></ul><ul><li>Depression / drowsiness </li></ul><ul><li>Renal calculi </li></ul>
  6. 6. Investigations <ul><li>S.calcium – increased </li></ul><ul><li>Phosphates – decreased </li></ul><ul><li>Alkaline phosphatase increased </li></ul><ul><li>PTH……………. </li></ul>
  7. 7. Management <ul><li>Re-hydration with normal saline 4-6 L </li></ul><ul><li>Pamidronate </li></ul><ul><li>Forced diuresis ( NS & lasix ) </li></ul><ul><li>Prednisolone </li></ul><ul><li>Calcitonin </li></ul><ul><li>Haemodialysis </li></ul><ul><li>Treatment of the cause </li></ul>

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