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Technology summit2018


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Technologies WG Meeting 2018 REG Summit

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Technology summit2018

  1. 1. REG Summit 2018 Amsterdam, 22nd March 2018 Technology Working Group Meeting
  2. 2. Agenda • Working Group Lead • Progress update and next steps for active studies • Areas for future research • Additional items
  3. 3. Attendees Richard Costello (chair)
  4. 4. A new lead for the technologies working group • John Blakey has requested to step down, while still being an active member of the group • The technologies group therefore needs a new lead • Any volunteers or recommendations?
  5. 5. Project update: Predicting the risk of future asthma exacerbations in a claims-based healthcare system • Objective o Characterise the frequent exacerbator subgroup of asthma patients. o Identifying individual risk factors and explore clusters of risk factors associated with increased future exacerbation risk o Validate REG’s UK Asthma Risk Prediction model, using administrative health data to identify patients at increased risk of future exacerbations.
  6. 6. Predicting the risk of future asthma exacerbations in a claims-based healthcare system • Status o Protocol complete o Seeking funding • Historical cohort study using population based clinical records from the BC Ministry of Health • 3 year study period Clinical and demographic characterisation of patients Univariate analysis to identify individual baseline factors associated with risk of recurrent exacerbations in the outcome period Multivariate analysis to identify composite groups of risk factors predictive of future risk Develop an individualised risk scoring tool Compare and contrast tool with UK clinical tools Methods Value Findings Interpretation Study Design Validation of the UK model in an administrative healthcare data system. Independent predictors (demographic and clinical) associated with future attacks
  7. 7. Progress update: Assessing the availability, functionality, utility and acceptance of smart inhalers: health care professionals opinions • New project following ERS 2017 meeting; to be run in-house by REG • Objective: o Define the smart inhalers currently on the market or in the process of coming to market, in terms of their functionality and mode of use o Evaluate the available data on efficacy, effectiveness and user acceptability of smart inhalers. o Identify key needs and opinions of health care professionals and determine whether those smart inhalers coming to market meet those needs.
  8. 8. Smart inhalers project • Rationale: o The wide variety of smart inhalers risk causing confusion for patients and logistical complications for physicians, and it is unlikely that all solutions are suitable for all patients or physicians o The role of smart inhalers on improving adherence and their cost- effectiveness is largely unknown o There is a paucity of evidence on feasibility and user acceptance of specific systems
  9. 9. Smart inhalers project • Methods: Systematic review – Search strategy o PubMed search for: – ((“electronic” OR “monitoring” OR “sensing” OR “digital” OR “smart” OR “mhealth”) AND “inhaler”) o Results reviewed for keywords, MeSH terms and inhaler names to include in second round of searching o Reference lists reviewed to identify further studies o All studies examined by two researchers, with a third in the case of disagreement Inclusion criteria: Evaluating, describing or using inhalers with a digital component which are currently available for use Exclusion criteria: Inhalers without a digital component, or a digital solution without a portable inhaler component
  10. 10. Smart inhalers project • Methods: Systematic review – data extraction o Study type, study population o Inhaler name and type o What data are captured and how o Data storage and availability o User opinion o Impact of use
  11. 11. Smart inhalers project • Methods: Delphi exercise o Three rounds: – Round 1: Free text answers to open-ended questions on the utility and challenges of smart inhalers in primary care – Round 2: Importance of themes (generated from round 1), rated on a Likert scale – Round 3: Level of agreement with statements (generated from round 2)
  12. 12. Smart inhalers project • Methods: Delphi exercise o Population – Primary care physicians, secondary care physicians, nurses, physiotherapists, pharmacists Should we include patients? Should we weight participation?
  13. 13. Other research ideas?
  14. 14. Any other business?