This presentation explores what happens when the infrastructural flows or metabolisms of the modern city, that so often come to be considered so ‘normal’ that urbanites may even come to see them as culturally banal, invisible, even boring, are suddenly interrupted or disturbed. Drawing from the 2009 Routeldge book 'Disrupted Cities: When Infrastructure Fails,' the presentation illustrates what happens when technical malfunctions, interruptions in supplies of resource, wars, terrorist attacks, public health crises, labour strikes, sabotage, network theft, extreme weather and other events usually considered to be ‘natural’ (floods, earthquakes, tsunami etc.) disrupt the flows of energy, water, transportation, communication and waste that are the very lifeblood of the contemporary city. Cases are drawn largely, but not exclusively, from North America and include very high profile events such as the September 2001 attacks on New York and Washington, the 2003 power blackout in the North Eastern seaboard, the devastation of New Orleans by Hurricane Katrina in 2005, and the infiltration of the global airline system by the SARS virus in 2003. The presentation complements these studies with analyses of much less well-known but equally important infrastructural disruptions: the deliberate targeting of city infrastructures in Iraq and the Occupied Territories by the US and Israeli state militaries; the hidden scleroris of city sewers caused by disgarded fats; the ways in which concern about disruptions is being used to politically reorganize and securitize global port systems in the wake of the ‘global war on terror;’ and the normal disruptions of city infrastructure that tends to characterize life in the burgeoning mega-cities of the global south – at least for the populations of informal settlements.