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AI in Oncology

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The given presentations share a specific use case from the medical field of oncology and outlines the potentials of applying artificial intelligence to it.

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AI in Oncology

  1. 1. Artificial Intelligence in Oncology Dr.-Ing. Matthieu-P. Schapranow MedTech Summit, Nuremberg May 23, 2019
  2. 2. ■  Case vignette: 65-year old, male, former smoker, COPD patient ■  How does the patient journey looks like? Patient Journey: Lung Cancer in 2024 Screening, Diagnosis, Treatment, and Prevention Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 2
  3. 3. ■  Case vignette: 65-year old, male, former smoker, COPD patient ■  How does the patient journey looks like? Patient Journey: Lung Cancer in 2024 Screening, Diagnosis, Treatment, and Prevention Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 3
  4. 4. ■  Personal risk score based on patient anamnesis, e.g. COPD or former smoker ■  Regular check-ups supported through direct notifications, e.g. annual respiratory screening recommended Patient Journey: Lung Cancer in 2024 Screening Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 4
  5. 5. ■  Lung function test ■  Low-dose CT scan of the lung ■  AI system supports radiologists in detecting lung tissue changes ■  Minimal invasive CTC test reveals cells carrying relevant genetic changes, e.g. EGFR+ and ERBB2+ ■  Biopsy from lung validated hypothesis Patient Journey: Lung Cancer in 2024 Diagnosis Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 5 https://www.plattform-lernende-systeme.de/anwendungsszenario-2.html
  6. 6. ■  AI-based therapy support based on, e.g. □  Clinical guidelines □  International medical knowledge □  Access to latest publications ■  à Surgery can be performed Patient Journey: Lung Cancer in 2024 Treatment Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 6 https://we.analyzegenomes.com/mkc/digiGipfel2018/
  7. 7. ■  Comparison of similar patients ■  Quantitative real-time analysis of therapy efficiency ■  Assessment of alternative therapy options ■  Bring clinical trials based on patient specifics to individual patients ■  à Adjuvant therapy based on specific combination of chemotherapy is performed Patient Journey: Lung Cancer in 2024 Treatment Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 7 https://we.analyzegenomes.com/mkc/digiGipfel2018/
  8. 8. ■  Federal Institute of Digital Health (DH), e.g. □  Maintains population data for a healthier society □  Provides access to subject-matter experts □  Supports development of innovative DH solutions ■  Data Donation Pass as citizen-facing tool: □  Enable sovereign use of healthcare data □  Control access to personal healthcare data, e.g. grant access to family members □  Donate de-identified data for a healthier society, e.g. to support specific research projects Patient Journey: Lung Cancer in 2024 Prevention Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 8 https://we.analyzegenomes.com/apps/data-donation-pass/
  9. 9. ■  150 MEUR national initiative to support adaption of digital health ■  HiGHmed consists of international partners from, e.g. hospitals, academia, and industry. ■  Clinical Use Cases □  Oncology □  Cardiology □  Infection control ■  Education: Curriculum for experts, e.g. data scientists, data stewards Medical Informatics Initiative HiGHmed Consortium Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 9
  10. 10. Our Approach: AnalyzeGenomes.com In-Memory Computing Platform for Big Medical Data Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 10 In-Memory Computing Platform Extensions for Life Sciences Data Exchange, App Store Access Control, Data Protection Fair Use Statistical Tools Real-time Analysis App-spanning User Profiles Combined and Linked Data Genome Data Cellular Pathways Genome Metadata Research Publications Pipeline and Analysis Models Drugs and Interactions Drug Response Analysis Pathway Topology Analysis Medical Knowledge CockpitOncolyzer Clinical Trial Recruitment Cohort Analysis ... Indexed Sources
  11. 11. Stay in Contact! Dr.-Ing. Matthieu-P. Schapranow Working Group Leader & Scientific Manager Digital Health Innovations Digital Health Center Hasso Plattner Institute Campus III, Rudolf-Breitscheid-Str. 187 14482 Potsdam, Germany we.analyzegenomes.com @AnalyzeGenomes Schapranow, MedTech Summit, May 23, 2019 AI in Oncology 11

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