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SwineFlu

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SwineFlu

  1. 1. What is Swine Flu? <ul><li>Swine Flu is an acute respiratory illness of </li></ul><ul><li>pigs which normally never attacks humans. </li></ul><ul><li>However, sporadic cases are </li></ul><ul><li>reported in the past rarely 2 or 3 per year, </li></ul><ul><li>until recently an epidemic occurred in men </li></ul><ul><li> rapidly becoming a global pandemic. </li></ul>
  2. 3. Swine Flu – Present status <ul><li>Only 12 cases were reported in USA in 5yrs </li></ul><ul><li>From 2004 to Apr`2009. </li></ul><ul><li>Apr`, May 2009 several 100s of cases world wide reported, H 1 N 1 strain SwineFlu. </li></ul><ul><li>In just 6 days pandemic phase 3 to phase 5 </li></ul><ul><li>was declared by WHO. </li></ul>
  3. 6. Swine Flu in Mexico <ul><li>From Mar`18 th to Apr`23 rd 854 cases. </li></ul><ul><li>59 Deaths were reported. </li></ul><ul><li>9 countries by mid April reported cases. </li></ul><ul><li>All cases have one thing in common. </li></ul><ul><li>H/O travel to Mexico or a contact history </li></ul><ul><li>with a confirmed case of Swine Flu. </li></ul>
  4. 7. Swine Flu Cases ( USA ) <ul><li>April 30 - 91 + 1 Death </li></ul><ul><li>May 1 - 141 + 1 Death </li></ul><ul><li>May 2 - 160 + 1 Death </li></ul><ul><li>May 3 - 226 + 1 Death </li></ul><ul><li>May 4 - 279 + 1 Death </li></ul><ul><li>May 5 - 403 + 1 Death </li></ul>
  5. 8. Indian Status of Swine Flu <ul><li>Only 4 Cases (Suspected). </li></ul><ul><li>To be confirmed by NIV Pune, </li></ul><ul><li>NICD Delhi. </li></ul><ul><li>As on May 1`st. 2009. </li></ul><ul><li>May 5 th the cases were 7. </li></ul><ul><li>All are proved negative by Lab tests. </li></ul>
  6. 9. Reassortant H 1 N 1 Virus
  7. 10. Antigenic shift in Swine Flu
  8. 11. Symptoms of Swine Flu
  9. 13. Transmission of Swine Flu.
  10. 14. Periodicity of strains of Swine Flu <ul><li>In 1998 H 1 N 1 was prevalent among Swines. </li></ul><ul><li>In 2004 H 3 N 2 was prevalent. </li></ul><ul><li>Present strains are supposed to be triple reassortant strains of Human, Avian, and </li></ul><ul><li>Swine Influenza virus. </li></ul>
  11. 15. Swine Flu Virus <ul><li>Typically cause outbreaks in swines seasonally. </li></ul><ul><li>In late Fall and Winter the outbreaks occur. </li></ul><ul><li>Dry weather and Cool Temperature. </li></ul><ul><li>The Virus H 1 N 1 Swine Flu was discovered </li></ul><ul><li>in 1930 in Swines. </li></ul>
  12. 17. Case definitions for swine Flu <ul><li>Influenza like illness (ILI) </li></ul><ul><li> *Sudden fever(>38 0 ) </li></ul><ul><li>*cough or sorethroat. </li></ul><ul><li> *Absence of other diagnosis. </li></ul><ul><li>Severe Acute Resp. Infection ( SARI) </li></ul><ul><li>> 5yrs. *Sudden fever(>38 0 ) </li></ul><ul><li>*cough or sorethroat. </li></ul><ul><li>*Dyspnea ----- *Requiring hospitalization. </li></ul><ul><li>< 5yrs. * Clinically suspected pneumonia. </li></ul><ul><li> *Requiring hospitalization </li></ul>
  13. 18. Case definitions for swine Flu <ul><li>Suspected case of Swine Flu (H 1 N 1 ) </li></ul><ul><li>Acute Febrile respiratory illness with onset </li></ul><ul><li>* within 7 days of close contact with a confirmed case of (H 1 N 1 ) inf. </li></ul><ul><li>* Within 7 days of travel to araeas where there are one or more confirmed cases. </li></ul><ul><li>* resides where there are one or more confirmed cases . </li></ul>
  14. 19. Case definitions for swine Flu <ul><li>Probable case of swine influenza (H 1 N 1 ) </li></ul><ul><li>* +Ve for influenza A, but unsubtypable for </li></ul><ul><li>H1 and H3 by influenza RT-PCR. </li></ul><ul><li>* Influenza rapid test or Influenza immunoflore- </li></ul><ul><li>scence assay(IFA) +Ve & Criteria of suspected </li></ul><ul><li>case fulfilled. </li></ul><ul><li>* Unexplained respiratory illness died with an </li></ul><ul><li>epidemiologically linked confirmed case. </li></ul>
  15. 20. Case definitions for swine Flu <ul><li>Close contact – Person within 6 feet of an ill person who is a confirmed , suspected or probable case. </li></ul><ul><li>Acute resp. illness defined as at least 2 of </li></ul><ul><li>* Rhinorea. </li></ul><ul><li>* Nasal congestion. </li></ul><ul><li>* Sorethroat. </li></ul><ul><li>* Cough. </li></ul><ul><li>* With or without fever. </li></ul>
  16. 21. Case definitions for swine Flu <ul><li>Confirmed case of Swine Influenza A (H 1 N 1 ) </li></ul><ul><li> Acute Febrile Resp. illness with Lab. Confirmed by </li></ul><ul><li>* Real time PCR . </li></ul><ul><li> </li></ul><ul><li>* Viral Culture. </li></ul><ul><li> * Four-fold rise in titre of Neutralizing Antibodies to Swine Influenza A (H 1 N 1 ) virus </li></ul>
  17. 22. Typical Clinical course. <ul><li>Contct with Virus occurs on Day 0. </li></ul><ul><li>Infection starts. Maximum Viral shedding </li></ul><ul><li>on Day 1. But almost asymptomatic . </li></ul><ul><li>Fever and lethargy occurs on Day 2. </li></ul><ul><li>4 – 5 Days infection & viral Shedding. </li></ul><ul><li>Day 7 - illness Completed. Virus Free. </li></ul><ul><li>Children, more prolonged 10 or more days. </li></ul>
  18. 23. The Course of the Complicated. <ul><li>Acute upper resp. tract illness. </li></ul><ul><li>Lower resp. tract illness. </li></ul><ul><li>* ARDS. </li></ul>
  19. 38. Thank You

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