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Kearns Sayre Syndrome


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Kearns Sayre Syndrome

  1. 1. Kearns-sayre syndrome Kearns-sayre syndrome is when the mitochondria in DNA becomes abnormal, and does not do its proper fucntions.
  2. 2. Description <ul><li>kearns-sayre syndrome is when the DNA in the mitochondria becomes abnormal </li></ul><ul><li>kearns-sayre syndrome affects everyone under the age of 20 </li></ul>
  3. 3. Test and Diagnosis <ul><li>kearns-sayre syndrome is caused the DNA in the mitochondria to not do its proper function </li></ul><ul><li>the symptoms are; paralysis of certain eye muscles (which gets worst over time) </li></ul><ul><li>degeneration of the retina (only the part that has to do with sight) </li></ul><ul><li>over time you may receive other symptoms, such as muscle weakness, difficulty walking or moving, brain damage, deafness, and heart disease </li></ul>
  4. 4. Test and Diagnosis <ul><li>since the mitochondria is in your whole body, this disease can affect other parts of your body </li></ul><ul><li>when doctors predicts that you have kearns-sayre syndrome, you may do two test </li></ul><ul><li>you can either have the doctors check the protein and lactate levels </li></ul><ul><li>you can also do a biopsy (sample of muscle) and look at the DNA in the mitochondria </li></ul><ul><li>there is not a cure for kearns-sayre syndrome, and it becomes worse as time goes on </li></ul>
  5. 5. A case of kearns-sayre syndrome <ul><li>The case report of the 26 years old female with Kearns-Sayre syndrome started about 16 years ago has some uncommon cardiological aspect apart from endocrine dysfunction, pancerebellar manifestation, progressive external ophthalmoplegia, neurosensorial hearing loss, and peripheral neuropathy among others abnormalities. Ophthalmologic examination showed dystrophic features in the cornea and retina. CT Scan of the brain showed generalized cerebral and cerebellar atrophy and dilatation of the ventricular system, etc. In the skeletal muscle biopsy the typical signs of atrophy and ragged-red fibers were seen. Laboratory tests, CT scan of the chest, ECG and Ultrasound studies showed signs of myocardiopathy, heart block, interventricular septal defect, renal lesions, liver disease and others. Different clinical trial was using looking for improvement of the patient's manifestations. </li></ul>
  6. 6. Images
  7. 7. Future of Kearns-sayre syndrome <ul><li>As the years go on, scientists will keep trying to discover a cure for the people who are and/or will suffer with this disease. </li></ul>