The immuassay handbook parte1


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The immuassay handbook parte1

  1. 1. The Immunoassay Handbook Theory and applications of ligand binding, ELISA and related techniques Fourth Edition Edited by David Wild Associate Editors Rhys John, Chris Sheehan, Steve Binder and Jianwen He AMSTERDAM • BOSTON • HEIDELBERG • LONDON • NEW YORK • OXFORD • PARIS • SAN DIEGO • SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO
  2. 2. Elsevier The Boulevard, Langford Lane, Kidlington, Oxford, OX5 1GB, UK 225 Wyman Street, Waltham, MA 02451, USA Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands Fourth Edition 2013 © 2013, 2005 David G. Wild. Published by Elsevier Ltd. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: Alternatively you can submit your request online by visiting the Elsevier web site at http://, and selecting Obtaining permission to use Elsevier material First Edition published by Macmillan Press (Basingstoke, UK) and Stockton Press (New York, USA) 1994 Second Edition published by Nature Publishing 2001 Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress ISBN: 978-0-08-097037-0 For information on all Elsevier publications visit our web site at While every care has been taken in compiling the information contained in this publication, the publishers and editor accept no responsibility for any errors or omissions. The reference intervals provided in this book are for specific methods, determined at a particular time, and using a single population of patients. Because of the inherent variability of immunoassays, they should not be applied to clinical situations. Therapeutic and toxic doses, and therapeutic ranges for drugs are only provided as a guide. They are not for clinical use. Printed and bound in Great Britain 13 14 15 16 17 10 9 8 7 6 5 4 3 2 1 Cover Credit: Rajeev Doshi