DISCOVERY OF AIDS & HIV:
First clinically observed:1981
Recognized by CDC:1981
Term coined in general press:
The term AIDS introduced:
DISCOVERY & NAMING:
Causative discovered: In 1983, by
Robert Gallo and Luc Montagnier
Causative identified: In 1984 by
research teams from
PASTEUR INSTITUTE in FRANCE and
NATIONAL INSTITUTE OF HEALTH
HIV is believed to have originated in non-
human primates in West-central Africa and
were transferred to humans in the early 20th century.
HIV is host specific. It infects and multiplies in
monkey but does not cause disease in them.
In case of AIDS virus, the host cell possesses a
CD4 receptor that allows that allows viral penetration.
As HIV infection continues in the host, decrease of
helper or CD4+ T-lymphocytes result in failure of
immune system and infected person is susceptible to
HIV has a liking for T-cells.
Two main clinical staging systems are used to classify HIV and
The WHO system uses the following
Primary HIV infection
Stage IV or AIDS
Average per act risk of getting HIV
by exposure route to an infected source
Blood transfusion 90%
Childbirth (to child) 25%
Needle-sharing injection drug use 0.67%
Percutaneous needle stick 0.30%
Sexual contact 3.75%
AIDS CAN’T BE TRANSMITTED
Day to day contact
One can’t get HIV from mosquitoes
It can’t be transmitted through animals and insects
The following fluids are not infectious:
SOME FACTS ABOUT AIDS
More than 35.3 million people are currently living
with HIV worldwide.
AIDS is the fourth leading cause of death globally.
December 1st is World AIDS Day.
Every 1 in 5 persons living with HIV are unaware
of their infection.