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emile
•NOTHING IS
NEW
THE THREAT
CONTINUES FROM
THE DEACADE
PASSED
280
254
224
128
187
29
0
100
200
300
400
500
600
700
1976 1995 2000 2003 2007 2012
death
infected
HISTORY REPEATS……
HISTORY OF THE
EPIDEMIC
First epidemic – 1976 sudan
Second epidemic- 1976 zaire
A rare picture of ebola
epidemic in 1976
1995 to 2012 epidemic
• 1995- democratic republic of congo
• 2000- uganda
• 2003- republic of congo
• 2004- russia
• 2007- DRC
• 2012- eastern DRC
EBOLA
A SPECIES OR A
GENUS???
EBOLA HAS ITS FIVE
SPECIES…
1. BUNDIBUGYO VIRUS
2. SUDAN VIRUS
3. TAI FOREST VIRUS
4. EBOLA VIRUS ZAIRE
5. RESTON VIRUS.
TRANSMISSION
• DIRECT CONTACT
• SEXUAL CONTACT
• PARENT 2 CHILD
• BREASTFEEDING
Animals to humans
PATHOPHYSIOLOGY
ENTERS HUMAN BODY
INFECTS ENDOTHELIAL, LIVER AND
IMMUNE CELLS
VIRUS CARRIED TO LYMPHNODES
PROGRAMMED CELLS DEATH OF WBCs
AND LYMPHOCYTES.
GENES REPLICATE TO VIRAL
PROPERTIES
INCREASED PRODUCTION OF
GLYCOPROTEINS.
BREAKDOWN OF ENDOTHELIAL LINING
HAEMMORHAGE,EDEMA AND SHOCK
SIGNS AND
SYMPTOMS
STAGE 1
STAGE 2
STAGE 3
LAST STAGE
Diagnostic tests
• BLOOD COUNT
• ANTIBODY CAPTURE (ELISA),
• ELECTRON MICROSCOPY
• POLYMERASE CHAIN REACTION
EBOV Real-Time RT-PCR Kit
“The BioFire Defense
FilmArray NGDS BT-E Assay
• It will take the Ebola cells, break
them open, expose the
[ribonucleic acid] in the Ebola
and match those with a target
that is identified.
• ISOLATION
• REHYDRATION
• IBUPROFEN
• HEPARIN
• ANTIBIOTICS.
• INTERFERON THERAPIES
• BLOOD TRANSFUSION
• ISOLATION
• REHYDRATION
• IBUPROFEN
• HEPARIN
• ANTIBIOTICS.
• INTERFERON THERAPIES
• BLOOD TRANSFUSION
• ISOLATION
• REHYDRATION
• IBUPROFEN
• HEPARIN
• ANTIBIOTICS.
• INTERFERON THERAPIES
• BLOOD TRANSFUSION
• ISOLATION
• REHYDRATION
• IBUPROFEN
• HEPARIN
• ANTIBIOTICS.
• INTERFERON THERAPIES
• BLOOD TRANSFUSION
• ISOLATION
• REHYDRATION
• IBUPROFEN
• HEPARIN
• ANTIBIOTICS.
• INTERFERON THERAPIES
• BLOOD TRANSFUSION
• ISOLATION
• REHYDRATION
• IBUPROFEN
• HEPARIN
• ANTIBIOTICS.
• INTERFERON THERAPIES
• BLOOD TRANSFUSION
• ISOLATION
• REHYDRATION
• IBUPROFEN
• HEPARIN
• ANTIBIOTICS.
• INTERFERON THERAPIES
• BLOOD TRANSFUSION
• INTENSIVE CARE
• DIALYSIS
• INTENSIVE CARE
• DIALYSIS
PREVENTION
• INFECTION CONTROL
• ISOLATION
• CONTACT TRACING
HOSPITAL PROTOCOL FOR
EBOLA HIT
• HANDLING PERSONAL PROTECTIVE
EQUIPMENT.
• REMOVAL
• ISOLATION
• FLUID CONTROL
• DISINFECTING
• NO NEEDLES
HOSPITAL PROTOCOL FOR
EBOLA HIT
• HANDLING PERSONAL PROTECTIVE
EQUIPMENT.
• REMOVAL
• ISOLATION
• FLUID CONTROL
• DISINFECTING
• NO NEEDLES
HOSPITAL PROTOCOL FOR
EBOLA HIT
• HANDLING PERSONAL PROTECTIVE
EQUIPMENT.
• REMOVAL
• ISOLATION
• FLUID CONTROL
• DISINFECTING
• NO NEEDLES
HOSPITAL PROTOCOL FOR
EBOLA HIT
• HANDLING PERSONAL PROTECTIVE
EQUIPMENT.
• REMOVAL
• ISOLATION
• FLUID CONTROL
• DISINFECTING
• NO NEEDLES
HOSPITAL PROTOCOL FOR
EBOLA HIT
• HANDLING PERSONAL PROTECTIVE
EQUIPMENT.
• REMOVAL
• ISOLATION
• FLUID CONTROL
• DISINFECTING
• NO NEEDLES
HOSPITAL PROTOCOL FOR
EBOLA HIT
• HANDLING PERSONAL PROTECTIVE
EQUIPMENT.
• REMOVAL
• ISOLATION
• FLUID CONTROL
• DISINFECTING
• NO NEEDLES
AND FOR YOUR PATIENCE LISTENING!!!

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