A Letter from
What the Science Says
Dr. Jialiu Liu Below are summaries and quotes of just a few of the more than 300
Honored medical professor studies completed on jiaogulan and its primary active compounds.
has researched plant for
more than 20 years Saponins isolated from jiaogulan were tested for their effect on lipid
metabolism. Administration of the saponins had beneficial effects
on serum levels of triglycerides, lipid peroxide, total cholesterol,
Dear FreeLife Friends,
phospholipids, and glutamic pyruvic transaminase.† Kimura, Y et al.
I am happy to take this opportunity to introduce myself, and also to introduce you to Natural Medicines/Japanese Society of Pharmacognosy. 1984; 37(3):272-275.
jiaogulan, an herb from my native southern China that I believe possesses the most
wide-ranging benefits for human health and wellness of any plant yet discovered. This
may seem like a bold statement, but having studied this remarkable tonic herb for more A study of 80 patients who took a gypenoside extract twice daily for
than 20 years, I can assure you that there is strong scientific support to back up my five months showed that the gypenosides could increase the levels of
passion for jiaogulan. cellular superoxide dismutase (SOD), one of the body’s very powerful
antioxidants.† Lu, G.Hl, et al. Guizhou Medical Journal. 1998; 22(3):25.
In my long career as a university professor of pathology in Guizhou, my research has
focused on helping the body to fight and protect against disease. In this regard, I have
studied and taught aspects of both the Traditional Chinese and modern Western
The Guiyang Medical College study found that athletes taking an oral
medical systems, which I have always believed can and should live in harmony. This is
best exemplified by jiaogulan, an herb with legendary traditional benefits that have form of jiaogulan and gypenosides experienced a definite adaptogenic
now been proven in rigorous modern research studies. response—they were more vigorous and alert, with quicker reflexes and
less nervousness.† Zhou, Ying-Na, et al. Journal of Guiyang Medical College.
My own experience with jiaogulan began in 1987 when I was asked by the Guizhou 1993; 18(4): 256.
government to lead a team of 16 scientists to investigate the healing properties of
plants from the Mt. Fanjing rainforest in southern China. After many years studying
hundreds of herbs, we ultimately came to the realization that jiaogulan was not only Chinese researchers recently determined that polysachharides in jiaogulan
the rainforest’s most precious gift, but was, in fact, nature’s greatest treasure. We began are “a very important ingredient” responsible for the herb’s ability to
to use jiaogulan in our medical university hospital with great success for a wide variety
enhance immune function.† Yang, X, et al. J Agric Food Chem. 2008 Aug
of conditions, and before long, it was also being used at numerous other hospitals
throughout China. This attracted the excited attention of scientists around the world,
and today there are more than 300 studies and research papers on jiaogulan from
China, Japan, Ireland, Germany, Italy, the Czech Republic, and even the United States.
A recent study from Taiwanese researchers found that jiaogulan was able
I am humbled that the Chinese government has chosen to honor me for my work, but to slow the abnormal development of human lung cells. The findings
what is even more pleasing to me is to be able to share my years of research experience confirm other studies on jiaogulan’s ability to protect cellular health.†
to help FreeLife formulate and bring to you the most complete and effective jiaogulan Lu, HF, et al. In Vivo. 2008 Mar-Apr;22(2):215-21.
tonic in the world—Jule of the Orient.
Warmly, A recent study from National Taiwan University investigated the immune-
Jialiu Liu, M.D
boosting potential for jiaogulan and found that the herb was able to
increase the production of different immune cells.† Huang, WC, et al.
Yakugaku Zasshi. 2007 May;127(5):889-96.
Quick Bio Dr. Jialiu Liu
Is widely acknowledged as the “Father of Jiaogulan,” and is hailed by scientists Australian researchers recently found that certain gypenosides in
as the leading jiaogulan researcher in the world. jiaogulan are able to protect the function of endothelial cells in the blood
Led a government-sponsored research team of 16 scientists studying the
vessels, thereby promoting cardiovascular health.† Huang, TH, et al. Eur
health-giving properties of jiaogulan for nearly a decade. J Pharmacol. 2007 Jun 22;565(1-3):158-65.
Enjoyed a long tenure as Professor of Pathology at Guiyang Medical College.
A study involving 610 people ages 50-90 found that the levels of the
Has been awarded numerous honors by the Chinese government, including the antioxidant SOD in this group increased 300%, to be equivalent of healthy
prestigious title “Advanced Scientist” by the Ministry of Public Health and the
National Committee of Science. Also honored with the “Outstanding Scientist”
teenagers. SOD is an extremely powerful antioxidant produced in the
award by the Guizhou Provincial Government. body.† Liu, Jialiu, et al. Journal of Guiyang Medical College. 1994: 19(1):17.
Jiaogulan: The “Secret of the South”
Why the “Immortality Herb” was unknown to ancient scholars
Jiaogulan is now acknowledged as perhaps the those familiar plants that grew in the northern
most health-giving herb in all of Traditional and central parts of the vast country, a region that
Chinese Medicine (TCM), but this was not always is known as the “ancient domain” of Traditional
so. For thousands of years, this remarkable plant Chinese Medicine. It would have been virtually
was unknown to TCM practitioners. In fact, the impossible in those days for the herbal scholars
earliest written description of jiaogulan came only to travel outside the ancient domain to the nearly
in the late 14th Century, and although that may seem inaccessible mountain forests of southern China
like ancient history to us in the West, 700 years by where jiaogulan was grown.
Chinese standards is almost like yesterday! Even
when jiaogulan was described in that first Ming Even had there been a means of traveling to the
Dynasty text, it was confused with another, wholly South, the ancient herbalists might well have
unrelated medicinal plant, and further descriptions chosen not to venture there. As elite scholars, they
in later textbooks did not give accurate accounts of may very well have believed that there was nothing
its properties. Perhaps because of the confusion and left for them to learn, especially from unschooled
inadequate descriptions, jiaogulan was virtually mountain folk. And yet, those good people of the
ignored and was little used in TCM formulas and southern mountains knew something that all of
prescriptions. the schooling in the world could not teach—they
understood the incredible power of jiaogulan, the
Besides the confusion, there was another good twisting vine with five-leafed clusters that they
reason for jiaogulan’s lack of mainstream lovingly called xiancao, the “Immortality Herb.”
acceptance—geography. The ancient founders Today, with the introduction of Jule of the Orient,
of TCM were an elite group of physicians and FreeLife invites the whole world to share in the
academicians, most of whom had been appointed tremendous health and longevity benefits of the
to the Emperor’s court in Beijing in the north of “Secret of the South.”
China. They chose their herbs, therefore, from
page 2 HealtHy living
Continued from page 1
ultimate jiaogulan tonic—a product
that would be based on the most
cutting-edge science and that would
Q&A with Haru Amagase, Ph.D.
Chief Scientific Officer
With a rich history in the nutraceutical industry, Dr. Amagase holds a doctorate in Pharmacology and
Pharmaceutical Sciences from Hiroshima University in Japan, and performed a Post-Doctoral Fellowship in
give people the health-promoting
Nutrition at Pennsylvania State University. With more than 27 years of experience in research and development,
results they wanted.” With that goal Amagase has published more than 30 scientific papers and holds 12 patents.
in mind, FreeLife began an in-
depth investigation, which included
traveling to China to meet with the Q. What is jiaogulan? function as hormones, they have a Q. Is Jule safe?
“Father of Jiaogulan”—Dr. Jialiu Liu, A. Jiaogulan is a member of the remarkable ability to influence the A. Jule is extremely safe and
same family as cucumbers, melons, body to produce a healthy balance jiaogulan has been consumed in Asia
a kindly and learned medical school
and gourds. It grows in five- of its own hormones.† Jiaogulan for thousands of years. However, if
professor who is widely regarded as leaf clusters, hence its botanical contains a broader and more you are pregnant or nursing, please
the leading jiaogulan researcher in name Gynostemma pentaphyllum. powerful range of saponins than seek out the advice of a nutritionally-
the world. Jiaogulan has a long history of use any other plant in nature, and its oriented medical practitioner before
in China, but is just now gaining bioactive gypenosides are not found using.
Creating the Premier popularity worldwide because of in any other species.
Jiaogulan Tonic new scientific research supporting
Dr. Liu explained that jiaogulan a wide range of health benefits that Q. Where is Jule manufactured?
may very well eclipse that of any Q. How much jiaogulan A. Jule is manufactured under
works as a potent, body-balancing
plant yet discovered. is in Jule? Federal Good Manufacturing
adaptogen. He emphasized the A. The exact amount of jiaogulan or Practices at an FDA-compliant facility
importance of using elements from the other supernutrients contained in the United States, and is made
the entire jiaogulan plant, including Q. Where does jiaogulan grow? in Jule is not disclosed. This is from the highest-quality ingredients
juice from the leaf, stem and root— A. Although jiaogulan is now considered one of the greatest that are sourced from reputable
not just the leaves as are used in most cultivated in many Asian countries, it intellectual assets of FreeLife®. vendors around the world.
other products. He also stressed that is widely acknowledged that the best However, rest assured that each
a complete jiaogulan tonic should and most effective jiaogulan grows in serving contains a highly efficacious
the forests and foothills of its original amount of active ingredients Q. Why are there
contain other synergistic Chinese natural flavors in Jule?
home in China. specifically formulated to deliver
herbs to complement jiaogulan’s maximum nutritional benefit. A. People in China have been
activity. Following Dr. Liu’s wise drinking herbal tonics and remedies
counsel, FreeLife scientists created Q. What are gypenoside saponins? for generations, but for those of us
a formula that they further enhanced A. Saponins are a diverse group of Q. Is Jule FDA-approved? in the Western world, they may be
by the addition of select high- chemicals found throughout the A. There is no official approval an “acquired taste.” High-quality
antioxidant, phytonutrient-rich super plant kingdom, and many have been process or certificate issued by jiaogulan is somewhat bitter by
studied for their health benefits. the Food and Drug Administration nature, but by use of a small amount
foods. The end result is Jule of the
Jiaogulan contains an elite subgroup (FDA) to approve the sale of any of natural fruit juice and flavor,
Orient, the premier jiaogulan tonic. of saponins called gypenosides, food or dietary supplement. The Jule is able to deliver a consistently
This energizing patent-pending blend which may prove to exert the most FDA has established stringent Good pleasant taste and aroma. If you
combines full-spectrum jiaogulan profound influence on human health. Manufacturing Practices (GMP) to prefer, you can mix Jule with water or
with 21 key supernutrients to give Their structure is similar to the ensure the safety and manufacturing a beverage of your choice.
you the adaptogens, phytonutrients, chemical structure of key hormones, of foods sold in the United States.
and antioxidants you need to live life and although gypenosides do not Jule is manufactured in a GMP-
to the fullest! compliant facility.
What’s in Jule of the Orient™?
While the patent pending blend of jiaogulan is the foundation of Jule™, this unique product also contains
21 other supernutrients for unmatched tonic and health-promoting benefits for optimal wellness
Jiaogulan. The immortality herb is Aronia Berry. One of the highest Jujube Fruit. One of the world’s Schisandra Berry. Promotes
considered as the premier adaptogen reported antioxidant scores on ORAC oldest fruits; used in Chinese energy, supports liver and kidneys,
to balance body systems and enhance scale.† medicine as tonic for 4,000 years. and supports a healthy heart and
energy production.† central nervous system.†
Astragalus Root. A staple of Luo Han Guo Fruit. Contains
Goji Berry. Contains glycoproteins Traditional Chinese Medicine to unique antioxidants that support Bilberry. Contains powerful
called Lycium barbarum improve immunity.† healthy immunity.† antioxidants to protect eyes, brain,
polysaccharides with wide-ranging and other organs.†
benefits for human health. Camu-Camu Fruit. Contains Pomegranate Fruit. Hundreds of
more natural Vitamin C than any studies validate its health-promoting Longan Fruit. Contains several
Açai Fruit. Has a very high other known botanical. effects. compounds, including ellagic acid,
antioxidant capacity and possesses a that bestow antioxidant and cell-
wide nutrient spectrum.† Cranberry. Promotes healthy Rhodiola Root. Used traditionally protective effects.†
urinary tract function.† in Tibet, northern China, and Eastern
Japanese Sophora Bud. The Europe as an adaptogenic tonic. Codonopsis Root. One of the
world’s richest source of the flavonoid Elderberry Fruit. Rich in most widely used Chinese tonic
quercetin, a powerful antioxidant.† flavonoids and other compounds to herbs; supports digestive, respiratory,
Blueberry. May protect the heart,
support immune function.† brain, and vascular system against and immune health.†
Amalaki Fruit. The centerpiece
of many traditional Ayurvedic free-radical damage.†
Ginger Root. Promotes healthy Cherry Juice. Contains 17
formulations; exerts natural pro- antioxidants; may help with joint
digestive function and may support Lychee Fruit. High in nutrients,
digestive properties.† discomfort.†
healthy blood and vascular health.† especially Vitamin C; supports
These statements have not been evaluated by the Food and Drug Administration. HealtHy living page 3
This product is not intended to diagnose, treat, cure, or prevent any disease.