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Malignant melanoma


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Dr. Travers gave this brief talk to the Melanoma Foundation's "Running for Cover" Boston Marathon team on Nov 16.

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Malignant melanoma

  1. 1. Robin L. Travers, MD SkinCare Physicians Boston Marathon Qualifier 2005-2011
  2. 2. <ul><li>The most serious form of skin cancer </li></ul><ul><li>Curable if recognized and treated early </li></ul><ul><li>In advanced state, serious illness and death </li></ul><ul><li>120,000 cases diagnosed every year </li></ul><ul><li>2010: 68,130 invasive melanomas diagnosed </li></ul><ul><li>4% of all skin cancers </li></ul><ul><li>80% of all deaths from skin cancers </li></ul>
  3. 4. <ul><li>Number of melanoma cases worldwide is increasing faster than any other cancer! </li></ul><ul><li>Doubling of melanoma incidence every 10-20 years </li></ul><ul><li>Even greater incidence rates among young women. </li></ul>
  4. 6. <ul><li>In the past decade, the risk of dying from cancer has dropped. But for several cancers, the mortality risk has risen. The most dramatic increase in mortality from 2000-2010 was found for lung cancer (in women) and for melanoma (for both genders) </li></ul>
  5. 8. <ul><li>Melanomas arise from melanocytes </li></ul><ul><li>Melanocytes produce pigment: MELANIN </li></ul><ul><li>Colors our skin, hair and eyes </li></ul><ul><li>Most melanomas arise in the skin </li></ul>
  6. 9. How Melanocytes Evolve Into Melanoma Miller AJ, Mihm MC Jr. N Engl J Med 2006;355:51-65.
  7. 11. <ul><li>Sun exposure </li></ul><ul><li>Moles </li></ul><ul><li>Skin Type </li></ul><ul><li>Family History </li></ul><ul><li>Personal History </li></ul><ul><li>Weakened Immune System </li></ul>
  8. 17. <ul><li>Breakthrough drugs for advanced and metastatic melanoma </li></ul><ul><li>New technologies for early detection </li></ul><ul><li>Primary care physicians becoming more skilled and performing more skin examinations </li></ul><ul><li>Mortality decrease in Australia </li></ul>
  9. 18. <ul><li>Wear sunscreen and seek shade </li></ul><ul><li>Wear sun protective clothing and sunglasses </li></ul><ul><li>Take your Vitamin D </li></ul><ul><li>Monitor your skin monthly, see your doctor yearly </li></ul><ul><li>Educate </li></ul><ul><li>Run 26.2 miles to support the Melanoma Foundation of New England! </li></ul>