Real Solutions to Chemical Problems
Our focus Our effort focused on the design and development of efficient catalytic systems for the selective hydrogenation ...
The hydrogenation and hydrogenolysis of furfural to 2-Methyl Furan. <ul><li>Coordination and heterolytic cleavage of H 2 <...
Synthesis of pre-catalysts <ul><li>Preparation of  cis - dichloride </li></ul>2. Unsaturation produces pre-catalyst. ( 1b ...
Synthesis, Characterization, and Reactivity  of Iridium(III) Dithiolate Complexes.
New Synthetic strategy with DMSO ( 6a )  77% yield ( 7a )  68% yield
New synthetic strategy with COD ( 8a ) 89 % yield ( 8b ) 82 % yield ( 9a ) 78 % yield ( 9b ) 45 % yield
Oxidative addition ( 7b )  56 % yield ( 10a ) 59 % yield ( 10a )   31 P{ 1 H} NMR (CDCl 3 ):  δ  94 (d, Ir-Pyr 2 ), 92 (d,...
Conclusions <ul><li>Several new complexes were synthesized and studied. </li></ul><ul><li>Novel synthetic strategies were ...
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Real solutions

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An overview of some chemistry I performed at UK.

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Real solutions

  1. 1. Real Solutions to Chemical Problems
  2. 2. Our focus Our effort focused on the design and development of efficient catalytic systems for the selective hydrogenation of C=O bonds in furan derivatives.
  3. 3. The hydrogenation and hydrogenolysis of furfural to 2-Methyl Furan. <ul><li>Coordination and heterolytic cleavage of H 2 </li></ul><ul><li>The protonation of the aldehyde. </li></ul><ul><li>Hydride attack on activated substrate generates alcohol. </li></ul><ul><li>The protonation of the alcohol </li></ul><ul><li>Hydride attack and elimination of water gives 2-methyl furan. </li></ul>
  4. 4. Synthesis of pre-catalysts <ul><li>Preparation of cis - dichloride </li></ul>2. Unsaturation produces pre-catalyst. ( 1b ) 31 P{ 1 H} NMR (CDCl 3 ): δ 83.5 (t), 56.8 (t) (62% yield) ( 2a ) 31 P{ 1 H} NMR (CDCl 3 ): δ 130.3 (t), 118.5 (t) (48% yield) ( 2b ) 31 P{ 1 H} NMR (CDCl 3 ): δ 134.6 (t), 133.4 (t) (56% yield)
  5. 5. Synthesis, Characterization, and Reactivity of Iridium(III) Dithiolate Complexes.
  6. 6. New Synthetic strategy with DMSO ( 6a ) 77% yield ( 7a ) 68% yield
  7. 7. New synthetic strategy with COD ( 8a ) 89 % yield ( 8b ) 82 % yield ( 9a ) 78 % yield ( 9b ) 45 % yield
  8. 8. Oxidative addition ( 7b ) 56 % yield ( 10a ) 59 % yield ( 10a ) 31 P{ 1 H} NMR (CDCl 3 ): δ 94 (d, Ir-Pyr 2 ), 92 (d, Ir-Ppyr 2 ). ( 7b ) 31 P{ 1 H} NMR (CDCl 3 ): δ 33.1 (d, Ir-PPh 2 ), 32.1 (d Ir-PPh 2 ).
  9. 9. Conclusions <ul><li>Several new complexes were synthesized and studied. </li></ul><ul><li>Novel synthetic strategies were developed for the preparation of these systems. </li></ul><ul><li>These new strategies incorporate the ability to tune ancillary ligands thus tuning the metal center for steric and electronic factors. </li></ul>

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