10a dev. ug

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10a dev. ug

  1. 1. Development ofUROGENITA L Dr mohan angadi SYSTEM
  2. 2. HIGHLIGHTS -functionally divided• Urinary system• Genital system
  3. 3. Introduction 2 embryonic structures that play an imp role in dev of UG system1. Intermediate mesoderm &2. Primitive Urogenital Sinus(UGS)-a part of cloaca.
  4. 4. Intermediate mesoderm  Click to edit the outline text format  Second Outline Level − Third Outline Level  Fourth Outline Level − Fifth Outline Level − Sixth Outline Level − Seventh Outline Level − Eighth Outline Level Ninth Outline LevelClick to edit Master text styles
  5. 5.  Click to edit the outline text format  Second Outline Level − Third Outline Level  Fourth Outline Level − Fifth Outline Level − Sixth Outline Level − Seventh Nephrogenic Outline cord LevelUrogenital ridge − Eighth Outline Level Gonadal Ninth Outline LevelClick to edit ridge Master text styles
  6. 6. Cloaca
  7. 7. Development of KIDNEY Three sets of kidneys develop in human embryos-evolution1. Pronephroi – in cyclostomes & fishes
  8. 8. 2. Mesonephroi
  9. 9. 3. Metanephroi
  10. 10. ampulla
  11. 11. Development of NEPHRONS
  12. 12. Ascent of kidneys: • Positional changes • Changes in blood supply
  13. 13. Anomalies of kidneys• Accessory(supernumerary)renal arteries
  14. 14. • Polar renal artery/ aberrant renal artery - hydronephrosis Accessory renal artery
  15. 15. • Renal agenesis/hypoplasia/ / hyperplasia – Unilateral • 1:1000 newborn • Males • Left kidney • Suspected in infants with single umbilical artery – Bilateral • 1:3000 newborn • Ass with oligohydromnios • Incompatible with life
  16. 16. • Abnormal rotation/Malrotated kidney : – Nonrotation – Incomplete rotation – Reverse rotation
  17. 17. • Anomalies of position/ Ectopic kidneys :  – - Pelvic kidney Click to edit the outline text format – - Crossed renal ectopia  Second Outline Level with− or without fusion Third Outline Level  Fourth Outline Level − Fifth Outline Level − Sixth Outline Level − Seventh Outline Level − Eighth Outline Level Ninth Outline LevelClick to edit Master text styles
  18. 18. • Anomalies of shape – Horseshoe kidney – Pancake kidney – Lobulated kidney
  19. 19. • Cystic kidney diseases – Autosomal recessive polycystic kidney disease – Multicystic dysplastic kidney disease
  20. 20. Development of ureter
  21. 21. Anomalies of ureter • Bifid & duplicate ureter 1
  22. 22. Ectopic ureter -urinary incontinence• Female Male  Click to edit the outline text format  Second Outline Level − Third Outline Level  Fourth Outline Level − Fifth Outline Level
  23. 23. Development of urinary bladder  Click to edit the outline text format Click to edit the outline  Click to edit the outline text format textSecond Outline Level format  − Third Outline Level  Second Outline Level  Second Outline Level  Fourth Outline − Third Outline Level − Third Outline Level Level  Fourth Outline  Fourth Outline − Fifth Outline Level Level Level − Fifth Outline − Fifth Outline − Sixth Outline Level Level Level − Sixth Outline − Sixth Outline − Seventh Level Level Level Outline − Seventh − Seventh −
  24. 24. Anomalies of urinary bladder • Urachal anomalies • Congenital megacystis & bladder diverticula
  25. 25. • Exstrophy of bladder/Ectopia vesicae
  26. 26. Development of urethra  Click to edit the outline text format  Second Outline Level − Third Outline Level  Fourth Outline Level − Fifth Outline Level
  27. 27. DEVELOPMENT OF MALE URETHRA1.Prostatic urethra: VUC (vesicourethral Above opening of canal)ejaculatory ductBelow ejaculatory ducts: DUGS (definitive urogenital sinus.)2.Membranous urethra: DUGS3.Penile urethra: DUGS4.Glandular urethra: Surface ectoderm
  28. 28. DEVELOPMENT OF FEMALE URETHRA It is homologous to upper part of prostatic urethra i. e. above the opening of ejaculatory ducts. Anomalies of urethra:• Urethral diverticula• Duplication• Abnormal commu with rectum• Hypospadiasis• Epispadiasis
  29. 29. Development of suprarenal glands:
  30. 30. Applied aspects• Ectopic adrenal tissue• Deep to capsule of kidney• Congenital adrenal hyperplasia – adrenogenital syndrome-in male – Pseudohermaphroditism-in female
  31. 31. Thanku

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