Society for Gynecologic Investigation 51st Annual Meeting

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Society for Gynecologic Investigation 51st Annual Meeting

  1. 1. Society for Gynecologic Investigation 51 st Annual Meeting NIH Workshop: Research Opportunities for Minority Investigators March 24, 2004 <ul><li>Estella C. Parrott, M.D., M.P.H. </li></ul><ul><li>Reproductive Sciences Branch </li></ul><ul><li>Center for Population Research </li></ul><ul><li>NICHD, NIH, DHHS </li></ul>
  2. 2. Reproductive Scientist Development Program (RSDP) <ul><ul><li>Grant mechanism is the K12: Mentored Clinical Scientist Development Award (Institutional) </li></ul></ul><ul><ul><li>Major Sponsor: NICHD </li></ul></ul><ul><ul><li>Candidates: Completed residency training in obstetrics and gynecology </li></ul></ul><ul><ul><li>All types of Ob/Gyn research </li></ul></ul><ul><ul><li>Four slots per year </li></ul></ul><ul><ul><li>Any top lab in the US </li></ul></ul><ul><ul><li>Training divided into two Phases (Basic Science Development Phase and Independent Research Phase) </li></ul></ul><ul><ul><li>Apply for seed grants year 1-2 and other funding years 3-5 </li></ul></ul><ul><ul><li>Candidates apply directly to program, not NIH </li></ul></ul><ul><ul><li>Program Director: Robert Jaffe, M.D., UCSF </li></ul></ul>
  3. 3. Women’s Reproductive Health Research Career Development Centers (WRHR) <ul><ul><li>Grant mechanism is the K12: Mentored Clinical Scientist Development Award (Institutional) </li></ul></ul><ul><ul><li>Major sponsor: NICHD </li></ul></ul><ul><ul><li>Cosponsors: ORWH, NCI </li></ul></ul><ul><ul><li>Mentored research experience for Ob/Gyn junior faculty leading to a career as an independent investigator </li></ul></ul><ul><ul><li>8 current Centers nationwide </li></ul></ul><ul><ul><li>Spring 2004, 10 more WRHR Centers available to recruit Ob/Gyn candidates for research training and career development </li></ul></ul>
  4. 4. WRHR Centers Program Components <ul><ul><li>Candidates: Completed residency training in obstetrics and gynecology or subspecialty training </li></ul></ul><ul><ul><li>Minimum of 3 Ob/Gyn scholars at each Center </li></ul></ul><ul><ul><li>Rolling availability </li></ul></ul><ul><ul><li>All types of Ob/Gyn research </li></ul></ul><ul><ul><li>Research Projects: basic, translational or clinical </li></ul></ul><ul><ul><li>Candidates apply directly to the WRHR Center, not NIH </li></ul></ul><ul><ul><li>At least 75% effort for up to 5 years </li></ul></ul>
  5. 5. Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) <ul><li>Grant mechanism is the K12: Mentored Clinical Scientist Development Award (Institutional) </li></ul><ul><li>Major sponsor ORWH </li></ul><ul><li>Trans-NIH (8 Institutes/Offices) and AHRQ </li></ul><ul><li>24 current program sites </li></ul><ul><li>Minimum of four scholars at each site </li></ul><ul><li>Scholars may have a clinical doctorate or PhD degree </li></ul><ul><li>All of women’s health research eligible </li></ul><ul><li>Candidates apply directly to program site, not NIH </li></ul><ul><li>At least 75% effort for up to 5 years </li></ul>
  6. 6. NIH Multidisciplinary Clinical Research Career Development Program <ul><li>Trans-NIH Initiative: </li></ul><ul><li>Grant mechanism is the K12: Mentored Clinical Scientist Development Award (Institutional) </li></ul><ul><li>Clinical research apprenticeship performed in mentored multidisciplinary team settings </li></ul><ul><li>Integrate clinical research training across an institution </li></ul><ul><li>Support career development of clinical researchers from a variety of disciplines </li></ul><ul><li>Formal training in the discipline of clinical research </li></ul><ul><li>Develop a national cadre of well trained clinical investigators </li></ul>
  7. 7. NIH Multidisciplinary Clinical Research Career Development Program <ul><li>Key features (at full implementation) </li></ul><ul><li>10 Training programs </li></ul><ul><li>20-25 Scholars per site </li></ul><ul><li>Flexibility in % effort </li></ul><ul><ul><li>At least 75% effort for up to 5 years </li></ul></ul><ul><ul><li>Allow at least 50% effort for surgical specialties </li></ul></ul><ul><li>Core didactic courses, required the first year </li></ul><ul><ul><li>Tuition support for advanced degrees </li></ul></ul><ul><li>Training in multidisciplinary team settings </li></ul><ul><li>Exposure to many disciplines </li></ul><ul><li>Postdoctoral level health professionals and junior faculty from a variety of disciplines and clinical specialties (e.g., MD, DDS, PhD, PharmD, RN/PHD) </li></ul><ul><li>Fall 2004: 5 Program Sites Operational </li></ul>
  8. 8. New NIH Policy Mentored Career Development K Award Recipients <ul><li>To facilitate transition to independent NIH research support, mentored K award recipients can also hold concurrent research grants (e.g., RO1, PO1 or UO1 ) as the PI or Subproject Director in the last two years of their career award </li></ul><ul><ul><li>Permits candidates to continue to benefit from the mentoring and protected time offered by the K award </li></ul></ul><ul><ul><li>Will adjust percent effort on K award (to no less than 50%) </li></ul></ul><ul><ul><li>Total level of research effort must not drop below 75% </li></ul></ul><ul><ul><li>See NIH Guide NOTICE: NOT-OD-04-007 </li></ul></ul><ul><ul><li>Contact NIH Program Staff for specific policy guidelines </li></ul></ul>
  9. 9. NIH Extramural Loan Repayment Programs (LRP) (www.lrp.nih.gov) <ul><li>Clinical Researchers LRP </li></ul><ul><li>Clinical Researchers from Disadvantaged Backgrounds LRP </li></ul><ul><li>Minority Health Disparities Research LRP </li></ul><ul><li>Pediatric Research LRP </li></ul><ul><li>Contraception and Infertility Research LRP </li></ul>
  10. 10. NIH Extramural LRP <ul><li>Repayment of the educational loan debt of qualified health professionals </li></ul><ul><li>Up to $35,000 per year of service </li></ul><ul><li>Covers 39% Federal tax on loan repayment </li></ul><ul><li>Must commit to a period of obligated service of no less than 20 hours a week for 2 years on the qualifying research project </li></ul><ul><li>Renewal contracts considered on annual basis </li></ul><ul><li>Next LRP Cycle: opens on September 1, 2004 and closes on December 15, 2004 </li></ul>
  11. 11. Combined Fellowship in Reproductive Endocrinology & Infertility <ul><li>Four government institutions: </li></ul><ul><ul><li>NICHD </li></ul></ul><ul><ul><li>Walter Reed Army Medical Center </li></ul></ul><ul><ul><li>National Naval Medical Center </li></ul></ul><ul><ul><li>Uniformed Services University of the Health Sciences </li></ul></ul><ul><li>Candidates: civilian and military residency graduates </li></ul><ul><li>Three-year training program for Ob/Gyn fellows in REI who will serve as faculty in military, government and academic institutions </li></ul><ul><li>Fellowship Director: James Segars, M.D. </li></ul>
  12. 12. NIH Research Funding Opportunities <ul><li>Program Announcement (PA) </li></ul><ul><li>Request for Applications (RFA) </li></ul><ul><li>Request for Proposals (RFP) </li></ul><ul><li>Research Supplements Program: Minority, Disability and Reentry </li></ul>
  13. 13. Program Announcement (PA) <ul><ul><li>Used by an institute to announce its interest in building or enhancing a research program in a particular area </li></ul></ul><ul><ul><li>Highlights interest in a specific area of research </li></ul></ul><ul><ul><li>Typically an ongoing solicitation, accepting grant applications for multiple receipt dates for up to 3 years </li></ul></ul><ul><ul><li>Usually, no specific funds set aside </li></ul></ul><ul><ul><li>May get special consideration if close to payline </li></ul></ul><ul><ul><li>Reviewed by regular study sections </li></ul></ul>
  14. 14. Request for Applications (RFA) <ul><li>Solicitations for grant applications addressing: </li></ul><ul><ul><li>a) a defined research topic of public health importance </li></ul></ul><ul><ul><li>b) representing scientific opportunities </li></ul></ul><ul><ul><li>c) research area in need of increased emphasis </li></ul></ul><ul><li>Funds set-aside for responsive applications that are meritorious </li></ul><ul><li>Usually, a one-time solicitation </li></ul><ul><li>Reviewed by a specially convened peer review panel </li></ul>
  15. 15. NIH Research Supplements Program <ul><li>Research Supplements for Underrepresented Minorities (PA-01-079) </li></ul><ul><li>Research Supplements for Individuals with Disabilities (PA-01-080) </li></ul><ul><li>Supplements to Promote Reentry into Biomedical and Behavioral Research Careers </li></ul><ul><li>(PA-01-081) </li></ul>
  16. 16. NIH Research Supplements Program <ul><li>Basic program components: </li></ul><ul><ul><li>Eligible candidates: High School, Undergraduate, Graduate, Postdoc or Investigator level </li></ul></ul><ul><ul><li>Underrepresented minorities are locally defined </li></ul></ul><ul><ul><li>Administrative supplement to a funded grant </li></ul></ul><ul><ul><li>Collaborate with a funded investigator on a research project </li></ul></ul><ul><ul><li>Established PI with a major NIH grant is eligible </li></ul></ul><ul><ul><li>Contact the PI </li></ul></ul><ul><ul><li>Provides funding for salary, supplies and travel </li></ul></ul><ul><ul><li>Relatively quick and non-bureaucratic </li></ul></ul><ul><ul><li>Work with NIH staff </li></ul></ul>
  17. 17. Cooperative Reproductive Science Research Centers at Minority Institutions <ul><li>Major sponsor: NICHD </li></ul><ul><li>Cosponsors: ORWH, NCMHD </li></ul><ul><li>Overarching Objectives: </li></ul><ul><ul><li>To expand research capacity in reproductive science at minority institutions </li></ul></ul><ul><ul><li>To create professional opportunities for minority investigators, especially those underrepresented within the scientific workforce </li></ul></ul><ul><ul><li>To cultivate an academic and research milieu that will stimulate interest among students and fellows to pursue research careers in reproductive science </li></ul></ul><ul><ul><li>To stimulate the development of a competitive research environment in reproductive science at minority institutions </li></ul></ul>
  18. 18. Cooperative Reproductive Science Research Centers at Minority Institutions <ul><li>Morehouse School of Medicine : Research projects at this Center integrate approaches at the molecular, cellular and organ levels to elucidate physiological mechanisms that govern sexual development, follicular maturation, luteolysis and spermatogenesis. [PI: David Mann, Ph.D.; Collaborator: Tony Plant, Ph.D., Univ. of Pitts.] </li></ul><ul><li>Meharry Medical College : Research s tudies at this Center examine the effect of OCPs on leiomyoma growth, whether metformin vs. placebo combined with lifestyle interventions improve reproductive markers in adolescent and adult women with PCOS, and the impact of racial differences on sex steroids and their correlation with bone density and architecture. [PI: PonJola Coney, M.D.; Collaborator : Richard Legro, M.D., Penn. State Univ.] </li></ul><ul><li>Charles R. Drew University of Medicine and Science : Therapeutic applications of androgens in normal women, women with hypopituitarism, and implications for conditions associated with loss of muscle mass and function as well as brain sexual differentiation provide several themes for research projects at this Center. [PI: Shalender Bhasin, M.D.; Collaborator: Gautam Chaudhuri, M.D., Ph.D., UCLA] </li></ul>
  19. 19. National Institutes of Health <ul><li>Including: </li></ul><ul><li>National Center on Minority Health and Health Disparities (NCMHD) </li></ul><ul><li>National Center for Research Resources (NCRR) </li></ul><ul><li>National Cancer Institute (NCI) </li></ul><ul><li>National Institute of Allergy and Infectious Diseases (NIAID) </li></ul><ul><li>National Institute of General Medical Sciences (NIGMS) </li></ul><ul><li>National Institute of Child Health and Human Development (NICHD) </li></ul>Opportunities for Minority Investigators and Minority Institutions at All Institutes, Centers and Offices 9434
  20. 20. For more information   <ul><li>  </li></ul><ul><li>Please visit the following web sites:   </li></ul><ul><li>http://www.nih.gov </li></ul><ul><li>http://www.nichd.nih.gov </li></ul><ul><li>http://grants1.nih.gov/training/index.htm </li></ul><ul><li>http://www.lrp.nih.gov </li></ul>

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