Lupus Caitlin Russell Science, Period 3 January 1, 2002
What is Lupus? <ul><li>An autoimmune disease </li></ul><ul><ul><li>When your body attacks itself  </li></ul></ul><ul><li>Y...
What Causes Lupus? <ul><li>Cause unknown, but suspect </li></ul><ul><ul><li>Genetic factors </li></ul></ul><ul><ul><li>Env...
What Causes Lupus? (cont’d) <ul><li>Genetic causes </li></ul><ul><ul><li>Hereditary, but no known gene to cause it </li></...
What Causes Lupus? (cont’d) <ul><li>Environmental causes </li></ul><ul><ul><li>Infections </li></ul></ul><ul><ul><li>Antib...
Symptoms of Lupus <ul><li>Flares are common </li></ul><ul><ul><li>Periods where symptoms are intense, then die down </li><...
Symptoms of Lupus (cont’d) <ul><ul><li>Skin rashes </li></ul></ul><ul><ul><ul><li>74% </li></ul></ul></ul><ul><ul><li>Anem...
Diagnosis of Lupus <ul><li>Difficult to diagnose Lupus </li></ul><ul><ul><li>Lupus symptoms mirror other diseases’ symptom...
Three Kinds of Lupus <ul><li>Discoid </li></ul><ul><li>Systemic </li></ul><ul><li>Drug-induced </li></ul>
Discoid Lupus <ul><li>Affects only the skin </li></ul><ul><li>Symptoms </li></ul><ul><ul><li>Rashes </li></ul></ul><ul><ul...
Discoid Lupus (cont.) <ul><li>10% of Discoid Lupus patients develop Systemic Lupus also. </li></ul><ul><ul><li>Can not be ...
Systemic Lupus <ul><li>Most severe and common type of Lupus </li></ul><ul><li>Can effect any part of the body </li></ul><u...
Drug-Induced Lupus <ul><li>Cause </li></ul><ul><ul><li>By taking certain drugs </li></ul></ul><ul><ul><ul><li>Hydralazine ...
Interview of a Lupus Patient <ul><li>How old were you when you got Lupus? And what kind of Lupus do you have? </li></ul><u...
Interview of a Lupus Patient <ul><ul><li>since childhood. I had my thyroid removed when I was 15 an inflamed thyroid, and ...
Interview of a Lupus Patient <ul><ul><li>They took more blood tests which pointed to Lupus. Also, my symptoms were those o...
Interview with a Lupus Patient  <ul><li>What are some of your most common symptoms? </li></ul><ul><ul><li>The symptom that...
Interview of a Lupus Patient <ul><li>What kind of medications do you take? </li></ul><ul><ul><li>I take Plaquenil which is...
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Caitlyn R. - Lupus

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Caitlyn R. - Lupus

  1. 1. Lupus Caitlin Russell Science, Period 3 January 1, 2002
  2. 2. What is Lupus? <ul><li>An autoimmune disease </li></ul><ul><ul><li>When your body attacks itself </li></ul></ul><ul><li>Your body can not tell the difference between foreign materials (antigens) and its own cells and tissues. </li></ul><ul><li>The immune system orders the antibodies to attack itself. </li></ul><ul><li>The auto-antibodies react with the bodies own antigens. This reaction forms immune complexes which build up. </li></ul>
  3. 3. What Causes Lupus? <ul><li>Cause unknown, but suspect </li></ul><ul><ul><li>Genetic factors </li></ul></ul><ul><ul><li>Environmental factors </li></ul></ul>
  4. 4. What Causes Lupus? (cont’d) <ul><li>Genetic causes </li></ul><ul><ul><li>Hereditary, but no known gene to cause it </li></ul></ul><ul><ul><li>Some people more genetically prone to Lupus </li></ul></ul><ul><ul><li>5% of children with parents who have it develop Lupus </li></ul></ul><ul><ul><li>10% of Lupus patients have a close relative with it too </li></ul></ul><ul><ul><li>Chromosomes 1 and 6 associated with Lupus in certain families </li></ul></ul>
  5. 5. What Causes Lupus? (cont’d) <ul><li>Environmental causes </li></ul><ul><ul><li>Infections </li></ul></ul><ul><ul><li>Antibiotics </li></ul></ul><ul><ul><li>Ultra-violet light </li></ul></ul><ul><ul><li>Extreme stress </li></ul></ul><ul><ul><li>Certain drugs </li></ul></ul>
  6. 6. Symptoms of Lupus <ul><li>Flares are common </li></ul><ul><ul><li>Periods where symptoms are intense, then die down </li></ul></ul><ul><li>Most common symptoms </li></ul><ul><ul><li>Achy joints </li></ul></ul><ul><ul><ul><li>Occurs in 95% of Lupus patients </li></ul></ul></ul><ul><ul><li>Fever more than 100 degrees F </li></ul></ul><ul><ul><ul><li>90% </li></ul></ul></ul><ul><ul><li>Arthritis </li></ul></ul><ul><ul><ul><li>90% </li></ul></ul></ul><ul><ul><li>Prolonged or extreme Fatigue </li></ul></ul><ul><ul><ul><li>81% </li></ul></ul></ul>
  7. 7. Symptoms of Lupus (cont’d) <ul><ul><li>Skin rashes </li></ul></ul><ul><ul><ul><li>74% </li></ul></ul></ul><ul><ul><li>Anemia </li></ul></ul><ul><ul><ul><li>71% </li></ul></ul></ul><ul><li>Other symptoms </li></ul><ul><ul><li>Kidney involvement, pain in chest, deep breathing, butterfly shaped rash on cheek and nose, sun or light sensitivity, hair loss, abnormal blood clotting, Raynaud’s phenomenon, seizures, mouth and nose ulcers. </li></ul></ul>
  8. 8. Diagnosis of Lupus <ul><li>Difficult to diagnose Lupus </li></ul><ul><ul><li>Lupus symptoms mirror other diseases’ symptoms, and Lupus symptoms often come and go </li></ul></ul><ul><li>No single lab test to diagnose Lupus </li></ul><ul><li>American College of Rheumatology (ACR) issued a list of 11 symptoms and tests to help diagnose Lupus patients. </li></ul><ul><ul><li>A person with Lupus experiences at least four of these symptoms or prove positive to at least 4 of these tests. The symptoms do not have to occur at the same time though. </li></ul></ul>
  9. 9. Three Kinds of Lupus <ul><li>Discoid </li></ul><ul><li>Systemic </li></ul><ul><li>Drug-induced </li></ul>
  10. 10. Discoid Lupus <ul><li>Affects only the skin </li></ul><ul><li>Symptoms </li></ul><ul><ul><li>Rashes </li></ul></ul><ul><ul><ul><li>On face, neck, and scalp </li></ul></ul></ul><ul><li>Diagnosis </li></ul><ul><ul><li>Examining a biopsy of the rash </li></ul></ul><ul><ul><ul><li>Diagnosed when biopsy shows that the skin without the rash contains things that are not normal. </li></ul></ul></ul>
  11. 11. Discoid Lupus (cont.) <ul><li>10% of Discoid Lupus patients develop Systemic Lupus also. </li></ul><ul><ul><li>Can not be prevented or predicted </li></ul></ul><ul><ul><li>Treatment of Discoid Lupus will not prevent Systemic Lupus from developing </li></ul></ul>
  12. 12. Systemic Lupus <ul><li>Most severe and common type of Lupus </li></ul><ul><li>Can effect any part of the body </li></ul><ul><li>Symptoms </li></ul><ul><ul><li>All symptoms apply </li></ul></ul><ul><li>Diagnosis </li></ul><ul><ul><li>Observing medical history and symptoms </li></ul></ul><ul><ul><li>Using the list made by the ACR </li></ul></ul><ul><ul><li>Blood tests </li></ul></ul>
  13. 13. Drug-Induced Lupus <ul><li>Cause </li></ul><ul><ul><li>By taking certain drugs </li></ul></ul><ul><ul><ul><li>Hydralazine </li></ul></ul></ul><ul><ul><ul><li>Procainamide </li></ul></ul></ul><ul><ul><li>Do not have to take drugs to get DI Lupus </li></ul></ul><ul><li>Symptoms </li></ul><ul><ul><li>Similar to Systemic symptoms </li></ul></ul><ul><li>Diagnosis </li></ul><ul><ul><li>The List of 11 symptoms by ACR </li></ul></ul><ul><li>DI Lupus usually stops after they stop taking the drug </li></ul>
  14. 14. Interview of a Lupus Patient <ul><li>How old were you when you got Lupus? And what kind of Lupus do you have? </li></ul><ul><ul><li>I was diagnosed with Discoid Lupus when I was 36. I had a sun sensitive spot that was red and itchy on my forehead. A biopsy indicated Lupus, and I was told to stay out of the sun. My doctor also ran a test for systemic Lupus later. It was for antinuclear antibody, and it came back positive. The specialist didn’t think I had systemic Lupus because I didn’t have the symptoms. When I was 50 I was finally diagnosed with systemic Lupus. My specialist then said there had been indicators of Lupus </li></ul></ul>
  15. 15. Interview of a Lupus Patient <ul><ul><li>since childhood. I had my thyroid removed when I was 15 an inflamed thyroid, and my first baby was premature. These are both symptoms of Lupus. </li></ul></ul><ul><li>Why did suspect you had Lupus? How does it effect your daily life? </li></ul><ul><ul><li>I was seeing my doctor for strept throat which I was tested for three times during a six month period and each came back negative. They found out I was anemic and put me on iron (which didn’t help). I was exhausted and was seeing a dermatologist because my arm was broken out from Lupus. I started to have pain in my throat and upper chest. This was from pleurisy. </li></ul></ul>
  16. 16. Interview of a Lupus Patient <ul><ul><li>They took more blood tests which pointed to Lupus. Also, my symptoms were those of Lupus. They sent me to a Lupus specialist who did more blood tests and put me on Prednisone. They did a test to see if Lupus would attack my major organs, and luckily, it came back negative. </li></ul></ul><ul><li>Do you know how you got Lupus? </li></ul><ul><ul><li>There is a possibility that it is a result of a genetic weakness, but it may also have been triggered by a severe reaction I had to a rabies vaccine when I was in my early 20’s </li></ul></ul>
  17. 17. Interview with a Lupus Patient <ul><li>What are some of your most common symptoms? </li></ul><ul><ul><li>The symptom that bothers me most is fatigue (from anemia). I have to take blood tests every two months. I also have stiff joints, a common symptom, but it may be from osteoarthritis, not Lupus. I have to adjust my daily activity Level so I don’t do too much in one day. I teach three days a week know instead of fulltime. I have to be careful about getting enough sleep. If I begin to get a cold, I take time off because it takes me longer to recover from illnesses. I have to work hard on being healthy because of this. </li></ul></ul>
  18. 18. Interview of a Lupus Patient <ul><li>What kind of medications do you take? </li></ul><ul><ul><li>I take Plaquenil which is an anti-malarial drug that fights fatigue. I also take Advil when I get stiff. I used to take Prednisone, but I don’t have to anymore because my disease isn’t as severe anymore as it used to be. </li></ul></ul><ul><li>Is there any research being done to find a cure or better treatment for Lupus? </li></ul><ul><ul><li>There are many groups doing research on the immune system which is a link to autoimmune diseases like Lupus. Also, since Lupus seems to attack mostly women, there are many groups trying to find a link between hormones and Lupus. </li></ul></ul>
  19. 19. The End

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