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Alcohol And Sleep Apnea


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Alcohol effects on sleep-disordered breathing.

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Alcohol And Sleep Apnea

  1. 1. Alcohol and Sleep Apnea Ken McKenney, Coordinator So. Ky. A.W.A.K.E.
  2. 2. Ethanol Usage? <ul><li>Per capita consumption of alcohol hasn’t changed since 1850 </li></ul><ul><li>In 1998, consumption was reported at 2.19 gallons (per year, per person 15 & older) </li></ul><ul><li>Beer=1.25; Spirits=0.63; Wine=0.31 </li></ul><ul><li>35% of adults don’t drink, so this amount is consumed by the remaining 65% </li></ul><ul><li>Men drink more than women (70% as compared with 61%) </li></ul>
  3. 3. Used Extensively as a Sleep Aid <ul><li>28% of insomniacs said they used alcohol to help fall asleep </li></ul><ul><li>Occasional insomniacs=3.6 nights per month </li></ul><ul><li>Chronic insomniacs=6.8 nights per month </li></ul><ul><li>67% overall describe alcohol as an effective or very effective method to induce sleep </li></ul>
  4. 4. Ball & Stick Model <ul><li>White= Hydrogen </li></ul><ul><li>Red= Oxygen </li></ul><ul><li>Black= Carbon </li></ul><ul><li>Metabolized quickly </li></ul>
  5. 7. A Normal Night’s Sleep <ul><li>Not necessarily a uniform process </li></ul><ul><li>Stages 1,2,3,4 of NREM and REM </li></ul><ul><li>Circadian Rhythm vs. “Sleep Debt” </li></ul>
  6. 9. Circadian vs. Sleep Debt
  7. 10. Definitions <ul><li>12 oz bottle of beer or wine cooler 1 </li></ul><ul><li>5 oz glass of wine 1 </li></ul><ul><li>1.5 oz of 80 proof distilled spirits 1 </li></ul><ul><li>These can yield BrAC’s as high as 0.105%! 2 </li></ul>1 Ancoli-Israel & Roth, 1991 2 Bennington and Heller, 1995
  8. 11. Alcohol’s Effects on Sleep <ul><li>Decreases Sleep Latency </li></ul><ul><li>Decreases TST </li></ul><ul><li>May increase SWS first half of night and decrease Growth Hormone (Takahashi et al. 1996 & Ekman et al. 1996) </li></ul><ul><li>Increases wake and light sleep second half of night (Williams et al11983 & Roehrs et al 1991) </li></ul>
  9. 12. Alcohol’s Effects on SDB <ul><li>Increases muscle relaxation </li></ul><ul><li>Increases # and Duration of Respiratory Events </li></ul><ul><li>Can cause apneic events even in people who otherwise do not have SDB! </li></ul>
  10. 14. Alcohol and the Aging <ul><li>Normal decrease in SWS during aging process </li></ul><ul><li>Awakenings of up to 20 times/night. </li></ul><ul><li>Increases susceptibility to SDB </li></ul><ul><li>Increases nighttime falls </li></ul>
  11. 15. Alcoholism and Sleep <ul><li>Increased sleep latency </li></ul><ul><li>Frequent awakenings </li></ul><ul><li>Decrease in subjective sleep quality associated with EDS </li></ul><ul><li>Increased REM </li></ul><ul><li>Severe withdrawal: periods of REM with awakenings </li></ul><ul><li>Some alcoholics tend to sleep poorly even years after abstinence! </li></ul>
  12. 16. A Final Note! <ul><li>Do not drink hand sanitizer! It can be deadly! </li></ul><ul><li>MedicineNet reported that 2 men drank this for it’s alcohol content! Both survived. </li></ul><ul><li>“ Active ingredient 63% Isopropyl alcohol, this “is higher than that in Vodka” </li></ul><ul><li>Industry considering “isopropanol” or “propane-2-ol” </li></ul>