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Dopamine

emergency medications

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Dopamine

  1. 1. Immediate precursor of noradrenaline
  2. 2.  Low doses (0.5-2mcg/kg/min) cause vasodilation of the renal and mesenteric arteries.  Renal vasodilation increases renal blood flow resulting in increased urine output and sodium excretion.  Low to moderate doses (2-10mcg/kg/min) increase myocardial contractility and stroke volume thereby increase cardiac output.  Systolic blood pressure and pulse pressure may rise with either no effect or a slight elevation in diastolic blood pressure.  Coronary blood flow and myocardial oxygen consumption increase.
  3. 3.  Higher doses (10mcg/kg/min or more) increases peripheral resistance, reduce urine output
  4. 4.  Onset of action 2-5minutes  Duration of action 5-10minutes
  5. 5.  Headache  Nausea  Vomiting  Angina  Respiratory difficulties  Decreased blood pressure Adverse reactions
  6. 6.  Knights, K & Kathleen, B 2011, Pharmacology for health professionals, Chapter 12, Elsevier, Chatswood, Australia. REFERENCE

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