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Olea25®
Hydroxytyrosol
Olive Leaf Extract
Neuroprotective Support
Role of Neurodegenerative Prevention
bauerhealthaction.c...
The Mediterranean
Diet
Health Benefits
Lower mortality rate in
countries around the
Mediterranean Region.
Major ingredient...
Olea25®
Hydroxytyrosol
The Medicinal Value of the
Olive Fruit and Leaf (Olea
Europaea)
Medicinal and Nutritional
Value
Ext...
Olea25®
Hydroxytyrosol
● Antioxidant
● Anti-inflammatory
● Cardioprotective
● Antitumoral
● Antidiabetic
● Antimicrobial
●...
Olea25®
Hydroxytyrosol
bauerhealthaction.com
Bioactive
Polyphenol from
Olive Leaf Extract
Polyphenols: Neuroprotective Actions
David Vauzour, “Dietary Polyphenols as
Modulators of Brain Functions: Biological
Acti...
Powerful
Antioxidant
Hydroxytyrosol
Strongest in vitro
Antioxidant potential
among all the Olive
Polyphenols
Visioli F, Be...
OLEA25®
Hydroxytyrosol Fights 5 Free Radicals
Description: Olea25 Olive Leaf 25% Hydroxytyrosol Powder
trademark by Certif...
Olea25®
Hydroxytyrosol
Oxidative Stress ⇒ Disease
● Aging
● Arteriosclerosis
● Cancer
● Neurodegenerative
Diseases
○ Parki...
Olea25®
Hydroxytyrosol
bauerhealthaction.com
Antioxidant
Cancer
Diabetes Mellitus
Neurodegenerative
Disease
Cardiovascular...
Sources of Polyphenol-
Hydroxytyrosol
(3,4-dihydroxyphenylethanol; DOPET)
Exogenous:
Ingestion of Natural
Products that co...
Olea25®
Hydroxytyrosol
● Hydroxytyrosol
Promotes the Cells
Own Defenses Against
Oxidative Stress
● Protects Neurogenesis
●...
Olea25®
Hydroxytyrosol
Imbalance between
Reactive Oxygen Species
(ROS) Production and
Antioxidant Defense
System
Neurodege...
Olea25®
Hydroxytyrosol
Alzheimer’s Disease
● Prevents Tau formation
● Protects neuronal cells
against toxicity
● Prevents ...
Olea25®
Hydroxytyrosol
● Improved synaptic
plasticity
● Down regulates
inflammatory activity
● Increases Glutathione
“brai...
Olea25®
Hydroxytyrosol
Resistance of Cellular
DNA Damage
● Resists Brain Cell
Oxidative Stress
● Protects Neuronal
Cells
C...
Olea25®
Hydroxytyrosol
Attenuates Toxicity
● ROS
● Nitric oxide
overproduction
● ↓ mitochondrial
membrane potential
● ↓ ce...
Olea25®
Hydroxytyrosol
● Mediated by
reduction if oxidative
& nitrosative stress
● Reduction in pro-
inflammatory
interleu...
Olea25®
Hydroxytyrosol
● Direct Scavenging ROS
generated during
oxidative stress
● Activates Cellular
Signaling Pathways
●...
Olea25®
Hydroxytyrosol
● Activates NrF2 in tissue
beneficial in
neurodegenerative
disease
● Increases activity of 3
Glutat...
Learn More
bauerhealthaction.com
Scientific-based nutraceutical for
your clients.
Olive Leaf extract utilizing
botanical extraction technology
Olea25™ is m...
Olea25®
Hydroxytyrosol
Applications of Olea25
Hydroxytyrosol
● Nutraceutical
● Skincare
● Beverage
● Functional Foods
baue...
Olea25®
Hydroxytyrosol
Distributor and Wholesale
Interest: CLICK HERE
● Medical Professional
● Health Care
Practitioner
Pr...
Olea25®
Hydroxytyrosol
bauerhealthaction.com
Contact Information
Randy Bauer
bauerhealthaction.com
877-925-8444
Hydroxytyrosol
REFERENCES:
Visioli F, Bellomo G, Galli C.. Free radical-scavenging properties of
olive oil polyphenols. Bi...
Hydroxytyrosol
REFERENCES:
Munoz-Marin, Javier, et al. "Cytoprotective effect of
hydroxytyrosyl alkyl ether derivatives af...
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Olea25® hydroxytyrosol neuroprotect cytoprotect

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Olea25® hydroxytyrosol is a polyphenol of olive leaf extract that supports health benefits of the Mediterranean Diet. Hydroxytyrosol is a potent antioxidant and anti-inflammatory that provides neuroprotective and cytoprotective support of neurodegenerative disease(alzheimer's disease) and has health benefits of heart health and metabolic syndrome.

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Olea25® hydroxytyrosol neuroprotect cytoprotect

  1. 1. Olea25® Hydroxytyrosol Olive Leaf Extract Neuroprotective Support Role of Neurodegenerative Prevention bauerhealthaction.com
  2. 2. The Mediterranean Diet Health Benefits Lower mortality rate in countries around the Mediterranean Region. Major ingredient of the Mediterranean Diet is the Olive and Olive Oil. bauerhealthaction.com
  3. 3. Olea25® Hydroxytyrosol The Medicinal Value of the Olive Fruit and Leaf (Olea Europaea) Medicinal and Nutritional Value Extracts of Olive Leaf have been used for Promoting Health and Preservation for Millennia. Polyphenol Hydroxytyrosol bauerhealthaction.com
  4. 4. Olea25® Hydroxytyrosol ● Antioxidant ● Anti-inflammatory ● Cardioprotective ● Antitumoral ● Antidiabetic ● Antimicrobial ● Neuroprotective Health Promoting Properties of Hydroxytyrosol bauerhealthaction.com
  5. 5. Olea25® Hydroxytyrosol bauerhealthaction.com Bioactive Polyphenol from Olive Leaf Extract
  6. 6. Polyphenols: Neuroprotective Actions David Vauzour, “Dietary Polyphenols as Modulators of Brain Functions: Biological Actions and Molecular Mechanisms Underpinning Their Beneficial Effects,” Oxidative Medicine and Cellular Longevity, vol. 2012, Article ID 914273, 16 pages, 2012. doi:10.1155 /2012/914273 bauerhealthaction.com Modulation of Neuronal Dysfunction by Dietary Polyphenols
  7. 7. Powerful Antioxidant Hydroxytyrosol Strongest in vitro Antioxidant potential among all the Olive Polyphenols Visioli F, Bellomo G, Galli C.. Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Commun (1998)247(1):60–4.10.1006/bbrc.1998.8735 Olea25® Hydroxytyrosol bauerhealthaction.com
  8. 8. OLEA25® Hydroxytyrosol Fights 5 Free Radicals Description: Olea25 Olive Leaf 25% Hydroxytyrosol Powder trademark by Certified Nutraceutical, Inc (Certificate of Analysis). bauerhealthaction.com
  9. 9. Olea25® Hydroxytyrosol Oxidative Stress ⇒ Disease ● Aging ● Arteriosclerosis ● Cancer ● Neurodegenerative Diseases ○ Parkinson’s Disease(PD) ○ Alzheimer’s Disease (AD) Antioxidant Capacity 15X higher than Green Tea 3X higher than CoQ10. bauerhealthaction.com
  10. 10. Olea25® Hydroxytyrosol bauerhealthaction.com Antioxidant Cancer Diabetes Mellitus Neurodegenerative Disease Cardiovascular Disease bauerhealthaction.com
  11. 11. Sources of Polyphenol- Hydroxytyrosol (3,4-dihydroxyphenylethanol; DOPET) Exogenous: Ingestion of Natural Products that contain HT, or it’s precursors. Endogenous: Derived from Dopamine Oxidative Metabolism Olea25® Hydroxytyrosol bauerhealthaction.com
  12. 12. Olea25® Hydroxytyrosol ● Hydroxytyrosol Promotes the Cells Own Defenses Against Oxidative Stress ● Protects Neurogenesis ● Modulates Mitochondrial Function Neuroprotective Support bauerhealthaction.com
  13. 13. Olea25® Hydroxytyrosol Imbalance between Reactive Oxygen Species (ROS) Production and Antioxidant Defense System Neurodegenerative Disease Causation bauerhealthaction.com
  14. 14. Olea25® Hydroxytyrosol Alzheimer’s Disease ● Prevents Tau formation ● Protects neuronal cells against toxicity ● Prevents Pro-Inflammatory Cytokines & Immunological Mediators Reversing Neurodegenerative Disease bauerhealthaction.com
  15. 15. Olea25® Hydroxytyrosol ● Improved synaptic plasticity ● Down regulates inflammatory activity ● Increases Glutathione “brain antioxidant” Crosses Blood-Brain Barrier bauerhealthaction.com
  16. 16. Olea25® Hydroxytyrosol Resistance of Cellular DNA Damage ● Resists Brain Cell Oxidative Stress ● Protects Neuronal Cells Cytoprotective Effects bauerhealthaction.com
  17. 17. Olea25® Hydroxytyrosol Attenuates Toxicity ● ROS ● Nitric oxide overproduction ● ↓ mitochondrial membrane potential ● ↓ cellular peroxide formation Cytoprotective Effects bauerhealthaction.com
  18. 18. Olea25® Hydroxytyrosol ● Mediated by reduction if oxidative & nitrosative stress ● Reduction in pro- inflammatory interleukin levels Cytoprotective Mechanisms bauerhealthaction.com
  19. 19. Olea25® Hydroxytyrosol ● Direct Scavenging ROS generated during oxidative stress ● Activates Cellular Signaling Pathways ● Induction of Phase II Detoxifying Enzymes via NrF2 Activation Biotransformation Antioxidant Properties bauerhealthaction.com
  20. 20. Olea25® Hydroxytyrosol ● Activates NrF2 in tissue beneficial in neurodegenerative disease ● Increases activity of 3 Glutathione related enzymes bauerhealthaction.com Mitochondria Protective
  21. 21. Learn More bauerhealthaction.com
  22. 22. Scientific-based nutraceutical for your clients. Olive Leaf extract utilizing botanical extraction technology Olea25™ is manufactured under GMP and ISO Certifications and the quality control system guarantees each item on the certificate of analysis and the traceability from raw material to final extract. bauerhealthaction.com Olea25® Hydroxytyrosol
  23. 23. Olea25® Hydroxytyrosol Applications of Olea25 Hydroxytyrosol ● Nutraceutical ● Skincare ● Beverage ● Functional Foods bauerhealthaction.com
  24. 24. Olea25® Hydroxytyrosol Distributor and Wholesale Interest: CLICK HERE ● Medical Professional ● Health Care Practitioner Provide Contact Information Click Here bauerhealthaction.com
  25. 25. Olea25® Hydroxytyrosol bauerhealthaction.com Contact Information Randy Bauer bauerhealthaction.com 877-925-8444
  26. 26. Hydroxytyrosol REFERENCES: Visioli F, Bellomo G, Galli C.. Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Commun (1998)247 (1):60–4.10.1006/bbrc.1998.8735 Feng, Zhihui et al. "Mitochondrial dynamic remodeling in strenuous exercise-induced muscle and mitochondrial dysfunction: regulatory effects of hydroxytyrosol." Free Radical Biology and Medicine 50.10 (2011): 1437-1446. Schaffer, Sebastian, and Barry Halliwell. "Comment on hydroxytyrosol induces proliferation and cytoprotection against oxidative injury in vascular endothelial cells: role of Nrf2 activation and HO-1 induction." Journal of agricultural and food chemistry 59.19 (2011): 10770-10771. Hashimoto, Tsuneichi, et al. "An endogenous metabolite of dopamine, 3, 4-dihydroxyphenylethanol, acts as a unique cytoprotective agent against oxidative stress-induced injury." Free Radical Biology and Medicine 36.5 (2004): 555-564. bauerhealthaction.com Olea25®
  27. 27. Hydroxytyrosol REFERENCES: Munoz-Marin, Javier, et al. "Cytoprotective effect of hydroxytyrosyl alkyl ether derivatives after oral administration to rats in a model of glucose–oxygen deprivation in brain slices." Journal of agricultural and food chemistry 60.31 (2012): 7659-7664. Farr, Susan A., et al. "Extra virgin olive oil improves learning and memory in SAMP8 mice." Journal of Alzheimer's Disease 28.1 (2012): 81-92. Zheng, Adi, et al. "Maternal hydroxytyrosol administration improves neurogenesis and cognitive function in prenatally stressed offspring." The Journal of nutritional biochemistry 26.2 (2015): 190-199. Rafehi, Haloom et al. "Investigation into the biological properties of the olive polyphenol, hydroxytyrosol: mechanistic insights by genome-wide mRNA-Seq analysis." Genes & nutrition 7.2 (2012): 343-355. bauerhealthaction.com Olea25®

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