Dedicated to Providing Superior Diagnostics Skin Cancer is on the RiseSkin Cancer is the most common form of cancer, with more than3.5 million cases per year. Early detection and treatment are keyto prevention and survival. It’s critical to pay attention to molesand other marks on your skin and get a skin exam once a year. Who Gets It?• 1 in 5 Americans• 1 in 3 Caucasians• Increasing incidence with age• Higher rate in older men & young women• Higher rate among people with family history of skin cancer• Higher rate among people with high sun exposure & tanning bed use
Dedicated to Providing Superior Diagnostics Do You Have Skin Cancer?• Basal cell carcinoma-most common cancer• Squamous cell carcinoma• Melanoma-one of most lethal forms of cancer• Pre-cancers• Others (e.g., lymphoma) The following photos show typical skin lesions that may be or develop into one of the top three forms of skin cancer. Photos from KDL Pathology and The Skin Cancer Foundation. Slide show adapted from www.cbsnews.com/2300- 204_162-10006772-5.html#ixzz1l4eJhlHU
Dedicated to Providing Superior Diagnostics Actinic Keratosis, All May Develop into Cancer Classic actinic keratosis - flat, pink and scaly. Although you might be able to pick this crusty lesion off with your fingers, it would grow back. • rough • sometimes bleed • tend to occur on sun-exposed skin, including the ears, face, scalp, backs of hands, neck. Actinic keratosis, marked with ink - in preparation for its removal.
Dedicated to Providing Superior Diagnostics Treat Precancerous LesionsThese red, scaly patches areActinic keratoses. These back-of-the-hand lesions arecommon in older golfers andothers who spend a lot of timeoutdoors.Without treatment, actinickeratoses can turn into a formof cancer known as squamouscell carcinoma.
Dedicated to Providing Superior Diagnostics Actinic Keratosis or Cancer?This could be an actinickeratosis or squamous cellcarcinoma. It should beremoved and sent to the labto determine.In general, the prognosis isgood for people withsquamous cell carcinoma.But a squamous cellcarcinoma that develops onthe lips or another mucousmembrane is more likely tospread (metastasize) - and inrare cases, proves deadly.
Dedicated to Providing Superior Diagnostics Basal Cell Carcinoma Classic basal cell carcinoma - the least dangerous form of skin cancer. Note the red color and the almost pearlescent look. These cancers seldom metastasize but can grow larger - and so should be removed. This basal cell carcinoma has turned into a bloody, oozy mess. Any lesion that bleeds and doesnt heal is suspect and should be examined right away.
Dedicated to Providing Superior Diagnostics Results of Sun Exposure Basal cell carcinomas like these and other cancers are common on the face because it gets so much sun exposure over the years. Mohs surgery can be performed on an Some basal cell outpatient basis to carcinomas, like minimizes scarring and this one, have a prevent disfigurement. raised border. Others not on the face can simply be burned off.
Dedicated to Providing Superior Diagnostics Scar? No, it’s basal cell carcinoma that looks like a scar. Atypical lesions like these can be tricky to diagnose. If its not the aftermath of a wound, it should likely be removed.
Dedicated to Providing Superior Diagnostics Squamous Cell Carcinoma This nodular ear lesion is a squamous cell carcinoma. These lesions are seldom fatal but can be disfiguring. Squamous cell carcinoma on the back of the hand. Squamous cell carcinoma of the nail.
Dedicated to Providing Superior Diagnostics It’s Deeper than it Looks Just a scab? No--this is a squamous cell carcinoma. Because skin cancers often extend deeper into tissue than they appear, the surgery required to remove this lesion is likely to be very extensive - and potentially disfiguring. Lesions should be removed before they get so big.
Dedicated to Providing Superior Diagnostics Is it a Mole? This isnt skin cancer but a dysplastic nevus (mole). These types of moles and lesions that appear irregular but are generally benign. If you have a lot of them, you may be more likely to develop skin cancer.Another dysplasticnevus. Theirregular borderand differentshades of color This close-up shot shows anothercan be signs of dysplastic nevus, but the dark colormelanoma - but is more typical of a melanoma andnot in this case. should be biopsied right away.
Dedicated to Providing Superior DiagnosticsMelanoma-One of the Deadliest Cancers Melanoma: • color - dark, almost black • irregular, scalloped border Over time, melanomas grow and thicken. The thicker the lesion, the worse the prognosis. This one should have been removed long ago.
Dedicated to Providing Superior Diagnostics Melanomas Can Occur Anywhere, Don’t Ignore Them Looks like a black-and- blue nail? No. Its a melanoma, and lesions like this can be deadly.This melanoma has beengrowing for years. Lesions Melanomas on the foot arethis extensive generally rare but sometimes deadly -cannot be successfully because people may mistaketreated - which is why early them for warts, delayingremoval is so essential treatment by a doctor.
Dedicated to Providing Superior Diagnostics Advancing Melanoma Classic melanoma with typical very dark coloration and varied (variegated) color. In addition, its highly asymmetrical. This melanoma is fairly advanced - as evidenced by the raisedA melanoma portion. As melanomas grow andthis thick is thicken, they become harder toalmost certain treat successfullyto prove lethal.
Dedicated to Providing Superior Diagnostics Melanoma Color Variation Heres a bluish-black melanoma. Sometimes melanomas start out as one color and slowly change The pink area next to this melanoma may be the result of regression, shrinking as the body tries This blackish lesion is to fight back. But the body a melanoma. But cant deal with a deadly melanomas can also lesion like this. It should be look reddish, or even removed promptly. bluish
Dedicated to Providing Superior DiagnosticsLarger Melanoma is more Deadly People sometimes put off going to the doctor even when they suspect they have a problem. In other cases, melanomas are allowed to grow big because they develop on a hard-to-see part of the body Check your skin monthly and don’t put off getting suspicious lesion checked.
Dedicated to Providing Superior Diagnostics The ABCD’s of Melanomas• Usually begin as small, flat colored lesion that spreads and thickens over time• May begin in pre-existing tumor (nevus) or as a new tumor in sun-damaged skin
Dedicated to Providing Superior Diagnostics Skin Cancer DetectionThe single most important sign of skin cancer is change in appearance of the lesion. • Have all suspicious lesions biopsied immediately • Skin biopsy typically covered by insurance plans • Clinical history may be misleading • Contact KDL for more information at firstname.lastname@example.orgWho finds them? • Patients- 50% • Practitioners- 25% • Family members – 20% • Melanomas are identified sooner by medical practitioners than patients
Dedicated to Providing Superior Diagnostics Keep a “WATCHFull Eye”• Whites• Adults• Tanning bed/ sun exposure• Changing lesions• History- personal or family history of skin cancer• Full skin examination• Eye – look for lesions which have features of skin cancer
Dedicated to Providing Superior Diagnostics KDL Pathology Accreditations & Licenses: CAP, CLIA, State of TN• Founded in 1997 by Dr. Paul B. Googe as Knoxville Dermatopathology Laboratory, a Staff Board-Certified: regional laboratory with national recognition Dermatopathologists, Ophthalmic and Anatomic• Only laboratory in East TN specializing in Pathologists pathology and diagnostic testing for diseases of the skin, nail and eye Affiliations:• Laboratory diagnostic reports correlate KDL Pathologists have histologic findings, ancillary testing and clinical teaching appointments at UT features Graduate School of Medicine and Vanderbilt University• Reports include therapeutic recommendation when warranted or requested Active member of TN Comprehensive Cancer• RapidResults biopsy testing services available TM Control Coalition