Dna Replication

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Dna Replication

  1. 1. Jessica Leung<br />Block D<br />DNA Replication<br />http://farm3.static.flickr.com/2272/2073342439_cfecc98a58.jpg<br />
  2. 2. Basic Information About DNA<br />
  3. 3. Nucleic Acids<br />Storage, Transmission, and use genetic information<br />Types: DNA and RNA<br />Made of Nucleotides<br />A pentose sugar, phosphate group, and a nitrogen-containing base<br />Phosphodiester linkages<br />http://upload.wikimedia.org/wikipedia/commons/2/2c/RNA_chemical_structure.GIF<br />
  4. 4. DNA Structure: 4 Key Points<br />Double stranded helix<br />Right handed<br />Anti-Parallel<br />Outer edges of the nitrogenous bases are exposed in minor and major grooves <br />http://upload.wikimedia.org/wikipedia/commons/9/9d/Water_drop_on_a_leaf.jpg<br />http://farm4.static.flickr.com/3131/2849019437_d670cd8086.jpg<br />http://farm4.static.flickr.com/3041/2735339035_62c0c6216d_o.jpg<br />http://images.wellcome.ac.uk/indexplus/obf_images/6a/1b/dba050918296decdf63926d0b3af.jpg<br />
  5. 5. 5’<br />3’<br /><ul><li>Double stranded helix
  6. 6. Right handed
  7. 7. Anti-Parallel
  8. 8. Complementary Base Pairings</li></ul>Major groove<br />Minor groove<br />3’<br />5’<br />
  9. 9. Base Pairings<br />DNA: Adenine, Cytosine, Guanine, Thymine<br />RNA: Adenine, Cytosine, Guanine, Uracil<br />
  10. 10. DNA REPLICATION!<br />
  11. 11. DNA Replication in Two Steps (the Idea)<br />Double Helix is unwound<br />New Nucleotides are added <br />http://images.wellcome.ac.uk/indexplus/obf_images/1f/db/51ca61b971d466050f9ed7d38edb.jpg<br />http://upload.wikimedia.org/wikipedia/commons/7/78/DNA.three-models.1.jpg<br />
  12. 12. The Big Idea<br />Ligase<br />Sliding DNA Clamp<br />http://upload.wikimedia.org/wikipedia/commons/5/51/Leading_strand_replication.png<br />http://www.multiplemomsrock.com/images/clamp.jpg<br />http://www.tsl.state.tx.us/ld/projects/trc/2006/manual/illos/glue.jpg<br />
  13. 13. Bibliography<br />Sadava, David, H. Craig Heller, Gordon H. Orians, William K. Purves, and David M. Hillis. Life The Science of Biology. New York: W. H. Freeman, 2006. Print.<br />

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