Protein_Synthesis_Flipbook_bbizousky

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Protein_Synthesis_Flipbook_bbizousky

  1. 1. Protein Synthesis By Blake Bizousky
  2. 2. Cytoplasm -Ribosomes
  3. 3. Cytoplasm -Ribosomes
  4. 4. Cytoplasm -Ribosomes
  5. 5. ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ -Ribosomes
  6. 6. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ -Ribosomes
  7. 7. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  8. 8. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ RNA Polymerase DNA Molecule -Ribosomes
  9. 9. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ RNA Polymerase DNA Molecule -Ribosomes
  10. 10. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ RNA Polymerase DNA Molecule -Ribosomes
  11. 11. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ RNA Polymerase DNA Molecule -Ribosomes
  12. 12. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  13. 13. Nucleus ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  14. 14. Nucleus mRNA Strand ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ -Ribosomes
  15. 15. Nucleus mRNA Strand ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ -Ribosomes
  16. 16. Nucleus mRNA Strand Nuclear Pore ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  17. 17. Nucleus mRNA Strand Nuclear Pore ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  18. 18. Nucleus Nuclear Pore ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  19. 19. Nucleus Nuclear Pore ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  20. 20. Nucleus Nuclear Pore ~~~~~~~~~T A C T T A G C G T A G A T T~~~~~~~~~~ ~~~~~~~~~A T G A A T C G C A T C T A A~~~~~~~~~~ DNA Molecule -Ribosomes
  21. 21. Cytoplasm
  22. 22. Ribosome Large unit AUG A AU CGC Small unit Start Condon Codon
  23. 23. Ribosome U AC Large unit AUG A AU CGC Small unit Start Condon Codon
  24. 24. Ribosome Large unit U AC AUG A AU CGC Small unit Start Condon Codon
  25. 25. Amino acid Ribosome tRNA Molecule Large unit Anticodon U AC AUG A AU CGC Small unit Start Condon Codon AUC U
  26. 26. Amino acid Ribosome tRNA Molecule Large unit UU A Anticodon U AC AUG A AU CGC Small unit Start Condon Codon AUC U
  27. 27. Amino acid Ribosome tRNA Molecule Large unit Anticodon UU A U AC AUG A AU CGC Small unit Start Condon Codon AUC U
  28. 28. Peptide bond U AC UU A AUG A AU Start Condon CGC Codon AUC UAA
  29. 29. Peptide bond GC G UU A AUG Start Condon A AU CGC Codon AUC UAA
  30. 30. Peptide bond UU A AUG Start Condon A AU GC G CGC Codon AUC UAA
  31. 31. Peptide bond U U A GC G AUG A AU CGC Codon AUC UAA
  32. 32. UAG GC G AUG A AU CGC Codon AUC UAA
  33. 33. GC G AUG A AU UAG CGC AUC Codon UAA
  34. 34. A AU GC G UAG CGC AUC UAA Stop Codon Codon
  35. 35. A AU UAG CGC AUC UAA Stop Codon Codon
  36. 36. GC on AUC UAA Stop Codon
  37. 37. C UAA Stop Codon
  38. 38. Amino acid in tertiary structure
  39. 39. Protein synthesis begins with transcription inside the nucleus. During transcription RNA polymerase binds to the DNA molecule at the promoter region and copies the coding region. RNA polymerase makes a single stranded mRNA copy of the DNA. RNA polymerase then stops copying at the terminating sequence and the mRNA strand makes it way out of the nucleus through a nuclear pore. Now in the cytoplasm, the mRNA strand binds with a ribosome. The ribosomes start reading the mRNA strand at the start codon. The ribosome brings in the correct anti-codon on a tRNA molecule which carries the certain amino acids which the codon coded for. The ribosome then brings in the rest of the tRNA. Between the tRNA molecules the amino acids form a peptide bond between each other. The tRNA then falls off, leaving the amino acid with the one which it bonded with. When the ribosomes has made it through all the codons it will reach the end codon. The end codon tells the ribosome to stop bringing in tRNA molecules. The polypeptide left behind now folds up into it’s tertiary form as a protein and goes on to do its function in the cell.

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