www.pronutritionist.net
Dietary intake and risk of
developing inflammatory bowel
disease: a systematic review of
the liter...
Page 2
Background
• The incidence of inflammatory bowel disease (IBD) is increasing
• Etiology of IBD is not fully underst...
Methods
• A systematic review of
– fully published case-control and cohort studies of the
association between pre-illness ...
Results (1/3): dietary intake and Crohn’s
Disease risk
Page 4 Hou JK et al. Am J Gastroenterol 2011;106:563-573. www.pronu...
Results (2/3): dietary intake and Colitis
Ulcerosa risk
www.pronutritionist.netHou JK et al. Am J Gastroenterol 2011;106:5...
Results (3/3)
• No consistent associations between total
carbohydrate intake and IBD were observed
www.pronutritionist.net...
Discussion
• This was the first systematic review on diet and incidence
of IBD
• Currently recommended high intake of PUFA...
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Dietary intake and ibd

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This meta-analysis provides data on dietary intake of main macronutrients/foods and their role in the development of infammatory bowel diseases (Hou et al. 2011)

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Dietary intake and ibd

  1. 1. www.pronutritionist.net Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature Hou JK et al. Am J Gastroenterol 2011;106:563-573 Page 1 Hou JK et al. Am J Gastroenterol 2011;106:563-573.
  2. 2. Page 2 Background • The incidence of inflammatory bowel disease (IBD) is increasing • Etiology of IBD is not fully understood, but many factors may influence such as genetics and environmental factors • The association between diet and IBD risk has not been clearly demonstrated Hou JK et al. Am J Gastroenterol 2011;106:563-573. www.pronutritionist.net
  3. 3. Methods • A systematic review of – fully published case-control and cohort studies of the association between pre-illness diet and IBD risk • 19 studies were included – 18 case-control studies, 1 cohort study – 2 609 IBD patients • 1 269 Crohn’s disease (CD) • 1 340 ulcerative colitis (UC) • > 4 000 controls Page 3 Hou JK et al. Am J Gastroenterol 2011;106:563-573. www.pronutritionist.net
  4. 4. Results (1/3): dietary intake and Crohn’s Disease risk Page 4 Hou JK et al. Am J Gastroenterol 2011;106:563-573. www.pronutritionist.net
  5. 5. Results (2/3): dietary intake and Colitis Ulcerosa risk www.pronutritionist.netHou JK et al. Am J Gastroenterol 2011;106:563-573.Page 5
  6. 6. Results (3/3) • No consistent associations between total carbohydrate intake and IBD were observed www.pronutritionist.netHou JK et al. Am J Gastroenterol 2011;106:563-573.Page 6
  7. 7. Discussion • This was the first systematic review on diet and incidence of IBD • Currently recommended high intake of PUFA, especially omega-6 fatty acids, may increase the risk of IBD disease • High intake of fiber, vegetables and fruit seems to be protective against IBD • Meat consistently increased the risk of IBD, whereas other protein sources (fish, eggs, dairy) had no effect • Biggest shortfall of this meta-analysis is its retrospective nature • More randomized studies are urgently needed as the prevalence of IBD increases worldwide Page 7 Hou JK et al. Am J Gastroenterol 2011;106:563-573. www.pronutritionist.net

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