2. Executive Summary
Pain is defined as an unpleasant feeling brought on by a noxious stimuli or injury. The expression of pain can drive someone to
stay away from harmful situations, defend injured tissues and avoid similar situations in future. Usually pain is classified as either
acute or chronic, and can also be classified into mild, moderate and severe on the basis of severity of pain. The most common
types of pain include back pain, orthopedic pain, cancer pain, post-surgical pain and neuropathic pain. Acute pain lasts for shorter
duration and gradually resolves as the injured tissue heals but chronic pain lasts longer than 12 weeks and persists even after
complete tissue healing.
Increasing incidences of chronic pain conditions globally, increasing recognition of the benefits relating to pain management by the
physicians and patients, introduction of innovative drugs for pain treatment, escalating diabetic and obese population, increasing
women’s population, growing drug spending and increasing healthcare expenditure are some of the significant factors driving the
growth of pain management market. However, the growth of the market is hindered by certain challenges including increasing
threats to branded drugs from generic introduction, rising death incidents from opioid consumption and limitations attached to
intravenous NSAIDs.
The pain management market is set to see changes in the treatment paradigm, where opioid drugs are being replaced by non-
opioids. The key trends of the market include rising opportunity for buprenorphine based drugs, development of several abuse-
deterrent drugs for chronic pain, pain relieving devices as the fastest growing healthcare sector, untapped local anesthetics market
for post-operative pain, substantial impact of chronic pain in the U.S. and presence of several certified physicians for pain
management in the U.S.
The report, “Global Pain Management Market” analyzes the current prevailing condition of the market along with its future scope of
development. The global market along with specific market of the U.S., is being discussed in the report. The major trends, growth
drivers as well as issues being faced by the industry are being presented in this report. The major players in the industry are being
profiled, along with their key financials and strategies for growth.
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3. The market for pain management will mature, driven by increasing incidences of chronic pain conditions globally,
increasing recognition of pain management by the physicians and patients, introduction of innovative drugs for pain
treatment and improving market demographics…
The global pain management market reached US$... billion in
the year 2014, registering an incline of ..% from US$... billion in
the prior year.
Cancer pain recorded ..% share in the global prescription drugs
market, followed by lower back pain that held ..% share. The
other two major segments included orthopedic pain and post-
operative pain with ..% and ..% share respectively
Of several prescription pain products in the U.S., Oxycodone
held the maximum share of ..% in the total sales value followed
by ..% share of Hydrocodone products for the year 2014.
Of several prescribed drugs for pain management in the U.S.,
Hydrocodone held the ..% share of the total prescription volume,
followed by Fentanyl, Oxycodone, and Lidocaine Patch with ..%,
..% and ..% share respectively.
Global Pain Prescription Drugs Market Share by Indication (2014)
Global Pain Management Market (2009-2014)
The U.S. Prescription Pain Market Share by Product Value (2014)
2009 2010 2011 2012 2013 2014
US$Billion
Sales Annual Growth
Cancer Pain Lower Back Pain Orthopaedic Pain
Post-Operative Pain Others
Oxycodone Hydrocodone Lidocaine Patch Fentanyl Oxymorphone Others
4. The unmet medical needs of pain management market allows new pain drugs drive the market rather than
interfering with the existing products…
The global chronic pain market reached US$.. billion in the year
2014, of which a major share of ..% was held by Opioid related
drugs followed by NSAIDs/COX-2s that held ..% share.
The global market for opioids reached US$.. billion in 2014,
increasing from US$.. billion in the preceding year.
The global sales of opioids will further reach US$.. billion by the end
of year 2017 registering a CAGR of ..% for the period spanning
2014-2017.
The neuropathic pain management market for seven major
economies reached US$.. billion in 2014, increasing from US$...
billion in previous fiscal.
Global Opioids Market by Value (2010-2017E)
Global Chronic Pain Market Share by Drug Classes (2014)
Neuropathic Pain Market by Value (2010-2014)
Opioids NSAIDs/ COX-2s Antiepileptics Antidepressants
2010 2011 2012 2013 2014 2017E
US$Billion
2010 2011 2012 2013 2014
US$Billion
5. The market for chronic pain is expected to rise in the coming years driven by increasing prevalence of
chronic lower back pain and osteoarthritis cases globally…
Increasing from US$.. billion in the year 2013, the market for post-
operative pain in the U.S. reached US$.. billion by the end of 2014.
For the year 2014, Lyrica (Pregabalin) dominated the neuropathic
pain treatment market with ..% share followed by antidepressant
duloxetine Cymbalta that held ..% share.
The market for post-operative pain is further estimated to reach
US$.. billion by the year 2022. The number of surgical procedures
will also increase from .. million in 2014, to nearly .. million
procedures by the year 2022.
The market for buprenorphine in the U.S. reached US$... billion in
2014, increasing from US$... billion in the previous year.
The U.S. Post-Operative Pain Market Share by Drug Classes (2014)
The U.S. Post-Operative Pain Market & Volume of Surgical Procedures (2012-2022E)
The U.S. Buprenorphine Market by Value (2008-2014)
2012 2013 2014 2022E
Million
US$Billion
Sales Number of Surgical Procedures
Strong Opioid Analgesics Simple Analgesics Dual-Acting Opioids
COX-2 Inhibitors Local Anesthetics Traditional NSAIDs
Anti-epileptic Drugs
2008 2009 2010 2011 2012 2013 2014
US$Billion
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