Brady women's health 2012


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Brady women's health 2012

  1. 1. Working AcrossSCOR, BIRCWH and CTSAPrograms: Interdisciplinary Synergy Kathleen Brady, MD, PhDAssociate Dean for Clinical and Translational Research Medical University of South Carolina S
  2. 2. MUSC Specialized Center for Translational Research (SCOR)S Funded 2002-?????S Research focus: gender differences in substance use / stress response S Translational research teamsS Second aim: to encourage growth of gender- based research campus-wide
  3. 3. Specific AimS To build a multi- disciplinary, translational program of research focused on gender-related issues in stress and substance use disorders at MUSC
  4. 4. StrategiesS Link with other programsS Bring in seasoned investigatorsS Build critical mass
  5. 5. Building Basic-Clinical Research Bridges: The Whole is Greater than the Sum of the PartsS Each project with unique focus, but interdependent, cross-talk, iterative process S medications studies S gonadal hormone findings S pharmacologic stressors S impulsivity studies S adverse childhood experiences
  6. 6. Bridging Basic and Clinical Research ProjectsTwo basic science, two clinical projects : projectsunique, but interdependent, cross-talk, iterativedevelopment Stress enhances impulsivity in human In vivo modulation of Imaging of brain changes laboratory paradigm identified brain regions in produced by the animal model pharmacotherapy for cognitive deficit Parallel test in the animal model Test of novel Test of novel established and applied pharmacotherapy for pharmacotherapy for in stress-enhanced human subjects impulsivity
  7. 7. Specific AimS To encourage the growth of gender-based research throughout the MUSC campus S Pilot project program S Interaction with Women Scholars Initiative S Interaction with centers throughout MUSC campus
  8. 8. Pilot Project ProgramS Funded by COM Dean of College and University ProvostS Received approximately 300 applications from every college and multiple departments, funded over 60 projectsS Has resulted in collaborations/gender-based research : S Aging Center S Ob-Gyn S Hollings Oncology Center S Crime Victims Center S Pediatrics S Center for Advanced Imaging Research S Alcohol Research Center S Pain Clinic - Anesthesiology
  9. 9. Specific AimS To attract and mentor young investigators and new investigators in the area of research, particularly patient-oriented research, in women’s health issues
  10. 10. Interaction with Training ProgramsS Post-Doctoral Fellowships in Alcohol and Drug Abuse: Translational ResearchS Drug Abuse Research TrainingS SPCTR: Roadmap Initiative focused on pre-doctoral research trainingS Master’s Training in Clinical ResearchS Neuroscience Graduate Program S NIMH-funded course in Biology of Neurologic and Neuropsychiatric DiseaseS Psychology Internship ProgramS Submitted K-12 application: BIRWCH
  11. 11. MUSC BIRCWH•Awarded September, 2007•Clinical and basic science scholars funded for 2-3 years each•Focus on gender differences in • Aging/ Cognitive decline • Addictions/ Mental health • Neuroscience
  12. 12. Areas of Overlap SCOR/BIRCWHS Monthly seminar series – SCOR investigators, BIRCWH scholars and mentors S Foster and model interdisciplinary “cross-talk”S Monthly journal clubS BIRCWH Scholars work on SCOR projectsS Collaboration across BIRCWH projects – basic/clinical interactionS Pilot project funds
  13. 13. CTSA : Institutional Home forClinical and Translational Science Healthcare organizations
  14. 14. CTSA MISSION To facilitate clinical and translational researchby providing research support services, research training and improving access to research- related resources.
  15. 15. CTSA MissionS Tremendous overlap with SCOR/BIRCWH – opportunity to leverage CTSA resources for program enhancementS SOCRATES – K-awardee “club”S Annual Mentorship retreatS Pilot project programS Thematic Research RetreatsS STAR consultationsS Core support/Research navigation
  16. 16. CTSA Research Resources Tech Transfer Regulatory & Bioethics Interdisciplinary Training/Mentoring Pilot ProjectsSCOR BIRCWH WOMEN’S HEALTH Journal Club Seminar Series S
  17. 17. Opportunities to Expand Funding S
  18. 18. CONCLUSIONSS Advocacy/awareness criticalS Find out about CTSA resourcesS Leverage existing strengths S Partner with existing centers, programs S Recruit “seasoned” investigators to explore gender differencesS Work across mentorship/training programs