Searching PubMedHIV Information Guide Peace Ossom July 2012
Searching PubMed• This is an instructional guide to assist health professionals in locating educational and professional evidence for the diagnosis and treatment of HIV in pregnant women and their infants postpartum.• For basic search instructions, please visit the following site: http://www.youtube.com/watch?v=Cephh8yXk3Il
First, identify the important concepts.• Example Question: Which method of antiretroviral prophylaxis— zidovudine alone, nevirapine alone, or zidovudine in combination with nevirapine— administered during labor or to the HIV-infected infant is best for reducing the chance of vertical transmission when HIV has been diagnosed in the mother late in her pregnancy?
Next Locate the Medical SubjectHeadings related to those topics.**Begin at pubmed.com and choose “MeSH” in the drop box.
After locating appropriate MeSH terms, add them to your search by clicking the “Add to search builder” button.•PubMed automatically explodes the term when searched in this method. Formore detailed instruction on search options, please visit this basic tutorialhttp://www.youtube.com/watch?v=Cephh8yXk3I
Be sure to use subheadings where appropriate. In this case I added “prevention and control.”• Search string:• (("HIV Infections"[Mesh] AND "Prevention and Control"[Subheading]) OR “HIV infections/prevention and control"[Mesh Terms]) AND “Zidovudine"[MeSH] AND "Nevirapine"[Mesh]
Refine by publication date and language to exclude items that may not be current or personally legible.• Also, conduct multiple searches using a combination of terms in order to locate all of the most relevant results.• Example strings: – ("Treatment Outcome"[Mesh] OR "Therapeutic Equivalency"[Mesh]) AND "Zidovudine"[Mesh] AND "Nevirapine"[Mesh] – "HIV Infections"[Mesh] AND prophylaxis[tw] AND "prevention and control"[Subheading]
During each search, analyze results for relevance and evaluate thelisted MeSH terms for the relevant articles in order to get ideas of terms to add to your searches. • Remember to evaluate for currency, details (type of research, # of participants, randomization, etc.), and authors in order to determine which results to trust.
For more information• PubMed: – Check out the PubMed Help page – Visit their Tours & Tutorials page• Dd• Personal: – Email: POssom@twu.edu – Website: http://myweb.twu.edu/~possom/index.htm