Tips to search the literature
Example with PubMed
Patrice CHALON, Msc
Knowledge manager, Centre fédéral d'expertise des so...
Approach
1. Identify your problem
2. Define a structured question
3. Find the best evidence
4. How valid is the study?
5. ...
1. IDENTIFY YOUR PROBLEM
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2010-09-10 3Patrice X. Chal...
Example
2010-09-10 4Patrice X. Chalon
2. DEFINE A
STRUCTURED QUESTION
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2010-09-10 5Patrice X...
Example
Source : Horsmans Y, Thiry N, le Polain M, Adler M, Colle I, Delwaide J, Michielsen P, Orlent H, Van Damme P, Huls...
Example (cont.)
(CHB OR (Hepatitis B
ADJ2 Chronic*))
AND
(NA OR (Nuclo?ide ADJ2
analogue) OR (Interferon
ADJ3 therap*))
20...
3. FIND THE BEST EVIDENCE
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2010-09-10 8Patrice X. Chal...
Databases for economic evaluations
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2010-09-10 9Patrice X....
MEDLINE (PUBMED)
http://www.pubmed.gov
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MedLine fact sheet
Producer National Library of Medicine (NLM, USA)
Time
coverage
1947-
Source 5400 worldwide journals cur...
PubMed additional content

The out-of-scope citations
(e.g., articles on plate tectonics or astrophysics)
from certain ME...
Example
Source : Horsmans Y, Thiry N, le Polain M, Adler M, Colle I, Delwaide J, Michielsen P, Orlent H, Van Damme P, Huls...
Search 1st
concept (patient / pathology)
MeSH database, available from : http://www.ncbi.nlm.nih.gov/sites/entrez?db=MeSH
...
Check MeSH term
2010-09-10 15Patrice X. Chalon
Major Heading? Explode?
Major Heading

Major topics of the article are
usually obtained from the title
and/or statement o...
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PubMed : results
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PubMed : Advanced search
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Search : 2nd
concept (therapy)
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Search : 2nd
concept (therapy) (cont.)
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PubMed search algorithm

PubMed uses an
algorithm to broaden
your search, the
algorithm associates
different terms

The ...
Search : 2nd
concept, term 2
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Combine searches (OR)
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Combine searches (AND)
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Search 3rd
concept (design)
Source : Horsmans Y, Thiry N, le Polain M, Adler M, Colle I, Delwaide J, Michielsen P, Orlent ...
Alternatives
2010-09-10 28Patrice X. Chalon
Thank you!
Copyrights: This work is released under Creative Commons License
2010-09-10 Patrice X. Chalon 29
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Cies 2010 literature searching pubmed

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Cies 2010 literature searching pubmed

  1. 1. Tips to search the literature Example with PubMed Patrice CHALON, Msc Knowledge manager, Centre fédéral d'expertise des soins de santé (KCE) 2010-09-10 1Patrice X. Chalon
  2. 2. Approach 1. Identify your problem 2. Define a structured question 3. Find the best evidence 4. How valid is the study? 5. What are the results? 6. How should I apply the results to patient care? Source: Guyatt G, Evidence-Based Medicine Working Group. Users' guides to the medical literature : a manual for evidence-based clinical practice. 2nd ed. New York: McGraw-Hill Medical; 2008. 2010-09-10 2Patrice X. Chalon
  3. 3. 1. IDENTIFY YOUR PROBLEM Image source : http://www.flickr.com/photos/crystaljingsr/3914729343/ 2010-09-10 3Patrice X. Chalon
  4. 4. Example 2010-09-10 4Patrice X. Chalon
  5. 5. 2. DEFINE A STRUCTURED QUESTION Image source : http://www.flickr.com/photos/crystaljingsr/3915514014 2010-09-10 5Patrice X. Chalon
  6. 6. Example Source : Horsmans Y, Thiry N, le Polain M, Adler M, Colle I, Delwaide J, Michielsen P, Orlent H, Van Damme P, Hulstaert F. Rapport coût-efficacité du traitement antiviral de l’hépatite B chronique en Belgique. Partie 1: Examen de la littérature et résultats d’une étude nationale. Health Technology Assessment (HTA). Bruxelles: Centre fédéral d’expertise des soins de santé (KCE). 2010. KCE Reports 127B. D/2010/10.2738/23. 2010-09-10 6Patrice X. Chalon
  7. 7. Example (cont.) (CHB OR (Hepatitis B ADJ2 Chronic*)) AND (NA OR (Nuclo?ide ADJ2 analogue) OR (Interferon ADJ3 therap*)) 2010-09-10 7Patrice X. Chalon
  8. 8. 3. FIND THE BEST EVIDENCE Image source : http://www.flickr.com/photos/crystaljingsr/3915514724 2010-09-10 8Patrice X. Chalon
  9. 9. Databases for economic evaluations Image source : http://www.flickr.com/photos/infomofo/4494714180/ 2010-09-10 9Patrice X. Chalon
  10. 10. MEDLINE (PUBMED) http://www.pubmed.gov 2010-09-10 10Patrice X. Chalon
  11. 11. MedLine fact sheet Producer National Library of Medicine (NLM, USA) Time coverage 1947- Source 5400 worldwide journals currently in 30 languages Topics Basic biomedical research and the clinical sciences, including nursing, dentistry, veterinary medicine, pharmacy, allied health, and pre-clinical sciences, life sciences including some aspects of biology, environmental science, marine biology, plant and animal science as well as biophysics and chemistry. Content Journal articles Indexation Medical Subject headings (MeSH), updated annually manual indexation based on full text reading Abstracts Author-written English abstracts Source : http://www.nlm.nih.gov/pubs/factsheets/medline.html 2010-09-10 11Patrice X. Chalon
  12. 12. PubMed additional content  The out-of-scope citations (e.g., articles on plate tectonics or astrophysics) from certain MEDLINE journals, primarily general science and chemistry journals, for which the life sciences articles are indexed for MEDLINE.  Citations that precede the date that a journal was selected for MEDLINE indexing  Some additional life science journals that submit full text to PubMedCentral and receive a qualitative review by NLM. 2010-09-10 12Patrice X. Chalon
  13. 13. Example Source : Horsmans Y, Thiry N, le Polain M, Adler M, Colle I, Delwaide J, Michielsen P, Orlent H, Van Damme P, Hulstaert F. Rapport coût-efficacité du traitement antiviral de l’hépatite B chronique en Belgique. Partie 1: Examen de la littérature et résultats d’une étude nationale. Health Technology Assessment (HTA). Bruxelles: Centre fédéral d’expertise des soins de santé (KCE). 2010. KCE Reports 127B. D/2010/10.2738/23. 2010-09-10 13Patrice X. Chalon
  14. 14. Search 1st concept (patient / pathology) MeSH database, available from : http://www.ncbi.nlm.nih.gov/sites/entrez?db=MeSH 2010-09-10 14Patrice X. Chalon
  15. 15. Check MeSH term 2010-09-10 15Patrice X. Chalon
  16. 16. Major Heading? Explode? Major Heading  Major topics of the article are usually obtained from the title and/or statement of purpose Explode  Explode option retains all narrower terms  PubMed explodes by default Source : http://www.nlm.nih.gov/bsd/disted/mesh/index.html 2010-09-10 16Patrice X. Chalon
  17. 17. 2010-09-10 17Patrice X. Chalon
  18. 18. PubMed : results 2010-09-10 18Patrice X. Chalon
  19. 19. PubMed : Advanced search 2010-09-10 19Patrice X. Chalon
  20. 20. Search : 2nd concept (therapy) 2010-09-10 20Patrice X. Chalon
  21. 21. Search : 2nd concept (therapy) (cont.) 2010-09-10 21Patrice X. Chalon
  22. 22. PubMed search algorithm  PubMed uses an algorithm to broaden your search, the algorithm associates different terms  The algorithm tries to find adequate MeSH term(s)  The algorithm uses truncation at the end  The search history only retains your query (!!!) 2010-09-10 22Patrice X. Chalon
  23. 23. Search : 2nd concept, term 2 2010-09-10 23Patrice X. Chalon
  24. 24. Combine searches (OR) 2010-09-10 24Patrice X. Chalon
  25. 25. Combine searches (AND) 2010-09-10 25Patrice X. Chalon
  26. 26. 2010-09-10 26Patrice X. Chalon
  27. 27. Search 3rd concept (design) Source : Horsmans Y, Thiry N, le Polain M, Adler M, Colle I, Delwaide J, Michielsen P, Orlent H, Van Damme P, Hulstaert F. Rapport coût-efficacité du traitement antiviral de l’hépatite B chronique en Belgique. Partie 1: Examen de la littérature et résultats d’une étude nationale. Health Technology Assessment (HTA). Bruxelles: Centre fédéral d’expertise des soins de santé (KCE). 2010. KCE Reports 127B. D/2010/10.2738/23. 2010-09-10 27Patrice X. Chalon
  28. 28. Alternatives 2010-09-10 28Patrice X. Chalon
  29. 29. Thank you! Copyrights: This work is released under Creative Commons License 2010-09-10 Patrice X. Chalon 29

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