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Duke Clinical Research Inst.


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Duke Clinical Research Inst.

  1. 1. Career Opportunities in Biostatistics at the Duke Clinical Research Institute
  2. 2. What is the DCRI? <ul><li>Academic research organization that integrates the scientific leadership of a major academic medical center with the operational capabilities of a large clinical research organization </li></ul><ul><li>A nonprofit i nstitute within Duke University </li></ul><ul><li>Mission </li></ul><ul><ul><li>Develop and share knowledge that improves the care of patients around the world through innovative clinical research </li></ul></ul>
  3. 3. What is the DCRI? <ul><li>850+ employees, including 120 clinical faculty/fellows </li></ul><ul><li>Coordinating center for national and international studies </li></ul><ul><li>Approximately 60 concurrent ongoing clinical trials </li></ul><ul><li>Over 1000 publications </li></ul><ul><li>Over 200,000 patients enrolled </li></ul><ul><li>Over 20 economics and quality of life studies within randomized trials </li></ul>
  4. 4. DCRI Research Areas <ul><li>Anesthesiology </li></ul><ul><li>Cardiology </li></ul><ul><li>Cardiothoracic surgery </li></ul><ul><li>CNS </li></ul><ul><li>Decision modeling </li></ul><ul><li>Dermatology </li></ul><ul><li>Economics </li></ul><ul><li>Endocrinology </li></ul><ul><li>ENT </li></ul><ul><li>Gastroenterology </li></ul><ul><li>Geriatrics </li></ul><ul><li>Hematology </li></ul><ul><li>Infectious disease </li></ul><ul><li>Nephrology </li></ul><ul><li>Oncology </li></ul><ul><li>Ophthalmology </li></ul><ul><li>Otolaryngology </li></ul><ul><li>Outcomes </li></ul><ul><li>Pediatrics </li></ul><ul><li>Primary care </li></ul><ul><li>Provider profiling </li></ul><ul><li>Quality of life </li></ul><ul><li>Rheumatology/immunology </li></ul><ul><li>Women’s health </li></ul>
  5. 5. Biostatistics at DCRI <ul><li>Approximately 60 Statisticians </li></ul><ul><ul><li>PhDs, both faculty and staff </li></ul></ul><ul><ul><li>Master’s level: Predominant! </li></ul></ul><ul><ul><li>Bachelor’s level: Only a handful </li></ul></ul>
  6. 6. Biostatistics Subgroups at DCRI <ul><li>Clinical Trials </li></ul><ul><li>Outcomes Research </li></ul>
  7. 7. Clinical Trials Statistics Group – Facts <ul><li>2/3 effort is on active clinical trials </li></ul><ul><li>1/3 effort is on analyses of accumulating databases toward a goal of medical publications and presentations </li></ul><ul><li>Funding for work is 1/2 from government, 1/2 from private industry </li></ul><ul><li>We have minimal turnover </li></ul>
  8. 8. <ul><li>Lead statistician </li></ul><ul><li>C oordinates all project responsibilities for the statistics group, and serves as the key statistical point person </li></ul><ul><li>Faculty statistician </li></ul><ul><li>Provides high-level thought leadership on design and analysis issues as well as DCRI SOP-required review and approval of analysis plans, specifications, and output </li></ul><ul><li>Statistical programmers </li></ul><ul><li>Program and validate analysis datasets and statistical output, and perform data transfers </li></ul>Clinical Trials Biostatistics Team
  9. 9. What I Enjoy About My Job <ul><li>A way to work in medicine without going to medical school! </li></ul><ul><li>Physician involvement gives real meaning to the analyses </li></ul><ul><li>Friendly community of statisticians to learn from; best statistical learning has come from peers </li></ul><ul><li>Family-friendly, flexible work environment </li></ul><ul><li>Occasional opportunities to travel and/or collaborate with external groups </li></ul>
  10. 10. What You Can Do Now <ul><li>Seek opportunities to work with researchers on analysis projects. Practical experience while you are in school is valuable! </li></ul><ul><li>Learn how to program – generous SAS programming experience can give you an edge </li></ul><ul><li>Focus on your people and language skills – technical abilities alone will not be enough to progress in a collaborative work environment </li></ul>