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Research via basic science


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Research via basic science

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Research via basic science

  1. 1. Research via basic science Paul B. Rothman, dean of the Medical Faculty and CEO of Johns Hopkins Medicine, US, on how basic sciences can encourage biomedical research
  2. 2. Contd.. At the foundation of any pioneering medical institute, should be research. Interdisciplinary, innovative and pioneering investigations create a path for excellence and ensure that the practice of medicine constantly advances. The opening of the Johns Hopkins Hospital in 1889, followed four years later by the Johns Hopkins University School of Medicine, ushered in a new era in medicine, integrating research with its instruction and practice. To move ahead, we need to heavily support basic sciences and encourage future generations of biomedical researchers. We need to understand the underlying mechanisms that give rise to disease. For example, idiopathic (of unknown cause) pulmonary fibrosis (IPF), a fatal disease that causes scarring and stiffening of the lungs, affects about 1,28,000 people in the United States, with nearly 50,000 new diagnoses each year.
  3. 3. Contd.. It turns out some cases of IPF may be caused by telomere shortening, the shortening of the ends of chromosomes. We would not know about that phenomenon had Carol Greider, a molecular biologist at Johns Hopkins and a Nobel Prize winner, not discovered in 1984 the telomerase enzyme that keeps chromosome ends long, while studying the organism Tetrahymena. That mechanism was not only fundamental to one-celled pond dwellers, but to all living organisms, including humans. Though there is no cure yet for IPF, we have more answers for patients and possible targets for drug discovery to someday treat the disease. Discoveries like this take a long time and require continued funding so that future generations can reap benefits.
  4. 4. For details and bookings contact:- Parveen Kumar Chadha… THINK TANK (Founder and C.E.O of Saxbee Consultants & Other-Mother Email Mobile No. +91-9818308353 Address:-First Floor G-20(A), Kirti Nagar, New Delhi India Postal Code-110015