The document discusses changes in US manufacturing employment from 1980 to 2010, with 7 million jobs lost. However, manufacturing is not declining but reinventing itself through new paradigms of sharing brainpower in open, collaborative innovation districts and the development of a new branch of the economy focused on smart products and new production methods leveraging technologies like sensors, wireless IT, and big data. Examples are given of former "rustbelt" cities like Akron, Albany, and Research Triangle Park transforming into "brainbelts" by building on research strengths in areas like polymers, nanotechnology, and attracting talent through university collaborations and venture capital investment in advanced manufacturing.