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Abrahams intro panel


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Abrahams intro panel

  1. 1. The Case for Personalized Medicine OSU Personalized Health Care Conference October 6, 2011 Columbus, Ohio Edward Abrahams, Ph.D. President Personalized Medicine Coalition
  2. 2. The Case for Personalized Medicine <ul><li>Shift emphasis in medicine from reaction to prevention </li></ul><ul><li>Enable the selection of optimal therapy and reduce trial-and-error prescribing </li></ul><ul><li>Make drugs safer by avoiding adverse drug reactions </li></ul><ul><li>Increase patient adherence with treatment </li></ul><ul><li>Improve quality of life </li></ul><ul><li>Revive drugs that failed in clinical trials or were withdrawn from the market </li></ul><ul><li>Help control the overall cost of health care </li></ul>
  3. 3. Major Drugs Ineffective for Many Source: Spear B, Heath-Chiozzi M, Huff J Clinical Trends Molecular Medicine 2001; 7(5):201-4.
  4. 4. Ineffective Therapies Waste Money <ul><li>Major Drug </li></ul><ul><li>Hypertension Drugs </li></ul><ul><li>Ace Inhibitors </li></ul><ul><li>Heart Failure Drugs </li></ul><ul><li>Beta Blockers </li></ul><ul><li>Anti Depressants </li></ul><ul><li>SSRIs </li></ul><ul><li>Cholesterol Drugs </li></ul><ul><li>Statins </li></ul><ul><li>Asthma Drugs </li></ul><ul><li>Beta-2-agonists </li></ul><ul><li>Cost of Ineffectiveness to Healthcare System </li></ul><ul><li>$390 million – $1.2 billion </li></ul><ul><li>$345 million – $575 million </li></ul><ul><li>$2.3 billion – $5.8 billion </li></ul><ul><li>$3.8 billion – $8.8 billion </li></ul><ul><li>$560 million – $1.0 billion </li></ul>
  5. 5. Personalized Medicine Coalition <ul><li>The Personalized Medicine Coalition, representing scientists, patients, providers and payers, promotes the understanding and adoption of personalized medicine concepts, services and products to benefit patients and the health system. </li></ul>