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Author(s): Gerald Abrams, M.D., 2009License: Unless otherwise noted, this material is made available under the termsof the...
Citation Key                          for more information see: http://open.umich.edu/wiki/CitationPolicyUse + Share + Ada...
M1 Patients and Populations:            NEOPLASIA II             Gerald D. Abrams MDFall 2008
MICROSCOPIC FEATURES OF       NEOPLASMS•  CONCEPT OF STROMA /   ANGIOGENESIS•  CONCEPT OF DIFFERENTIATION•  GRADING / STAG...
CANCER CELLS AND STROMA  G.D. Abrams, University of Michigan Medical School
CANCER CELLS AND STROMA      SCIRRHOUS  G.D. Abrams, University of Michigan Medical School
NORMAL COLONIC MUCOSA  G.D. Abrams, University of Michigan Medical School
COLON CANCER, MODERATELY     DIFFERENTIATED   G.D. Abrams, University of Michigan Medical School
NORMAL BRONCHIAL MUCOSA   G.D. Abrams, University of Michigan Medical School
CANCER OF THE BRONCHUS      ANAPLASTIC  G.D. Abrams, University of Michigan Medical School
GRADING OF NEOPLASMS•  ASSESSMENT OF THE DEGREE OF   DIFFERENTIATION OF A NEOPLASM•  BASED ON THE RESEMBLANCE OF   THE NEO...
WELL DIFFERENTIATEDSQUAMOUS CELL CARCINOMA G.D. Abrams, University of Michigan Medical School
MODERATELY DIFFERENTIATEDSQUAMOUS CELL CARCINOMA G.D. Abrams, University of Michigan Medical School
POORLY DIFFERENTIATEDSQUAMOUS CELL CARCINOMA G.D. Abrams, University of Michigan Medical School
STAGING OF NEOPLASMS•  ASSESSMENT OF THE EXTENT OF   PROGRESSION OF A NEOPLASM IN THE   BODY•  BASED ON THE SIZE AND EXTEN...
HISTOPATHOLOGIC DIAGNOSIS      OF NEOPLASMS•  DIAGNOSIS AS A PREDICTION•  EVALUATION OF:     -ARCHITECTURAL ARRANGEMENT   ...
INVASIONG.D. Abrams, University of Michigan Medical School
NORMAL COLONIC EPITHELIAL                     CELLSG.D. Abrams, University of Michigan Medical School
NEOPLASTIC COLONIC                 EPITHELIAL CELLSG.D. Abrams, University of Michigan Medical School
NORMAL SQUAMOUS         EPITHELIUMG.D. Abrams, University of Michigan Medical School
DYSPLASTIC SQUAMOUS     EPITHELIUMG.D. Abrams, University of Michigan Medical School
CARCINOMA IN SITUG.D. Abrams, University of Michigan Medical School
CELLULAR FEATURES             OF ANAPLASIAG.D. Abrams, University of Michigan Medical School
PAP SMEAR                       NORMAL CELLSG.D. Abrams, University of Michigan Medical School
PAP SMEAR                MALIGNANT CELLSG.D. Abrams, University of Michigan Medical School
NEOPLASIA IIIGerald D. Abrams
CLINICAL CONSEQUENCES       OF NEOPLASMSBENIGN     LOCAL MECHANICAL EFFECTS     LOCAL COMPLICATIONS     SYSTEMIC ENDOCRINE...
NOMENCLATURE OF        NEOPLASMS•  BASED ON     TISSUE OF ORIGIN     BENIGN OR MALIGNANT
EPITHELIAL NEOPLASMS•  ADENOMA!!!ADENOCARCINOMA•  PAPILLOMA...PAPILLARY CARCINOMA•  CYSTADENOMA.....           CYSTADENOCA...
ADRENAL CORTICAL ADENOMA   Source Undetermined
PANCREAS, ISLET CELL     ADENOMADepartment of Pathology, University of Michigan
COLON, ADENOMADepartment of Pathology, University of Michigan
COLON, ADENOMADepartment of Pathology, University of Michigan
Image of sketch  of papilloma    removed
OROPHARYNX, PAPILLOMA G.D. Abrams, University of Michigan Medical School
OVARY                      CYSTADENOMASource Undetermined
OVARY                      CYSTADENOMASource Undetermined
PENIS, SQUAMOUS CELL     CARCINOMASource Undetermined
VULVA, SQUAMOUS CELL     CARCINOMA    Source Undetermined
CERVIX, SQUAMOUS CELL      CARCINOMA     Source Undetermined
TONGUE, SQUAMOUS CELL     CARCINOMA Department of Pathology, University of Michigan
LARYNX, SQUAMOUS CELL     CARCINOMA     Source Undetermined
ESOPHAGUS, SQUAMOUS CELL       CARCINOMA      Department of Pathology, University of Michigan
STOMACH, ADENOCARCINOMA    Source Undetermined
COLON, ADENOCARCINOMA   Department of Pathology, University of Michigan
COLON, ADENOCARCINOMA  Source Undetermined
LUNG, SQUAMOUS CELL     CARCINOMA   Source Undetermined
LUNG, SQUAMOUS CELL     CARCINOMA Department of Pathology, University of Michigan
BRONCHUS, SQUAMOUS CELL      CARCINOMA   Department of Pathology, University of Michigan
BRONCHUS, SQUAMOUS CELL      CARCINOMA   Department of Pathology, University of Michigan
OVARY          CYSTADENOCARCINOMASource Undetermined
OVARY          CYSTADENOCARCINOMASource Undetermined
SUPPORTING TISSUE           NEOPLASMS•    LIPOMA!!!!LIPOSARCOMA•    CHONDROMA!CHONDROSARCOMA•    FIBROMA!!! FIBROSARCOMA• ...
COLON, LIPOMADepartment of Pathology, University of Michigan
UTERUS, LEIOMYOMAS Department of Pathology, University of Michigan
BONE, OSTEOSARCOMADepartment of Pathology, University of Michigan
MUSCLE,RHABDOMYOSARCOMADepartment of Pathology, University of Michigan
LYMPHOID / HEMATOPOIETIC       NEOPLASMS•  LYMPHOMA(S)•  LEUKEMIA(S)
LYMPHOMASource Undetermined
RETROPERITONEUM,   LYMPHOMADepartment of Pathology, University of Michigan
SPLEEN, LYMPHOMADepartment of Pathology, University of Michigan
KIDNEY, LYMPHOMA Department of Pathology, University of Michigan
CNS NEOPLASMS•  MENINGIOMA•  GLIOMA
BRAIN, GLIOMADepartment of Pathology, University of Michigan
NEOPLASMS WITH MIXED      DIFFERENTIATION•  CARCINOSARCOMA•  TERATOMA           BENIGN           MALIGNANT
OVARY, TERATOMADepartment of Pathology, University of Michigan
OVARY, TERATOMADepartment of Pathology, University of Michigan
OVARY, TERATOMADepartment of Pathology, University of Michigan
Additional Source Information                             for more information see: http://open.umich.edu/wiki/CitationPol...
Slide 49: Department of Pathology, University of MichiganSlide 50: Department of Pathology, University of MichiganSlide 51...
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08.25.08 - 08.27.08: Neoplasia II & III

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08.25.08 - 08.27.08: Neoplasia II & III

  1. 1. Author(s): Gerald Abrams, M.D., 2009License: Unless otherwise noted, this material is made available under the termsof the Creative Commons Attribution–Non-commercial–Share Alike 3.0License: http://creativecommons.org/licenses/by-nc-sa/3.0/We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize yourability to use, share, and adapt it. The citation key on the following slide provides information about how youmay share and adapt this material.Copyright holders of content included in this material should contact open.michigan@umich.edu with anyquestions, corrections, or clarification regarding the use of content.For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use.Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosisor a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Pleasespeak to your physician if you have questions about your medical condition.Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.
  2. 2. Citation Key for more information see: http://open.umich.edu/wiki/CitationPolicyUse + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (USC 17 §105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation LicenseMake Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (USC 17 § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (USC 17 § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
  3. 3. M1 Patients and Populations: NEOPLASIA II Gerald D. Abrams MDFall 2008
  4. 4. MICROSCOPIC FEATURES OF NEOPLASMS•  CONCEPT OF STROMA / ANGIOGENESIS•  CONCEPT OF DIFFERENTIATION•  GRADING / STAGING
  5. 5. CANCER CELLS AND STROMA G.D. Abrams, University of Michigan Medical School
  6. 6. CANCER CELLS AND STROMA SCIRRHOUS G.D. Abrams, University of Michigan Medical School
  7. 7. NORMAL COLONIC MUCOSA G.D. Abrams, University of Michigan Medical School
  8. 8. COLON CANCER, MODERATELY DIFFERENTIATED G.D. Abrams, University of Michigan Medical School
  9. 9. NORMAL BRONCHIAL MUCOSA G.D. Abrams, University of Michigan Medical School
  10. 10. CANCER OF THE BRONCHUS ANAPLASTIC G.D. Abrams, University of Michigan Medical School
  11. 11. GRADING OF NEOPLASMS•  ASSESSMENT OF THE DEGREE OF DIFFERENTIATION OF A NEOPLASM•  BASED ON THE RESEMBLANCE OF THE NEOPLASM TO THE NORMAL TISSUE OF ORIGIN
  12. 12. WELL DIFFERENTIATEDSQUAMOUS CELL CARCINOMA G.D. Abrams, University of Michigan Medical School
  13. 13. MODERATELY DIFFERENTIATEDSQUAMOUS CELL CARCINOMA G.D. Abrams, University of Michigan Medical School
  14. 14. POORLY DIFFERENTIATEDSQUAMOUS CELL CARCINOMA G.D. Abrams, University of Michigan Medical School
  15. 15. STAGING OF NEOPLASMS•  ASSESSMENT OF THE EXTENT OF PROGRESSION OF A NEOPLASM IN THE BODY•  BASED ON THE SIZE AND EXTENT OF THE PRIMARY, AND ON THE PRESENCE OR ABSENCE OF REGIONAL AND DISTANT METASTASES
  16. 16. HISTOPATHOLOGIC DIAGNOSIS OF NEOPLASMS•  DIAGNOSIS AS A PREDICTION•  EVALUATION OF: -ARCHITECTURAL ARRANGEMENT -RELATION OF NEOPLASTIC CELLS TO NORMAL SURROUNDINGS -CYTOLOGIC FEATURES OF NEOPLASTIC CELLS
  17. 17. INVASIONG.D. Abrams, University of Michigan Medical School
  18. 18. NORMAL COLONIC EPITHELIAL CELLSG.D. Abrams, University of Michigan Medical School
  19. 19. NEOPLASTIC COLONIC EPITHELIAL CELLSG.D. Abrams, University of Michigan Medical School
  20. 20. NORMAL SQUAMOUS EPITHELIUMG.D. Abrams, University of Michigan Medical School
  21. 21. DYSPLASTIC SQUAMOUS EPITHELIUMG.D. Abrams, University of Michigan Medical School
  22. 22. CARCINOMA IN SITUG.D. Abrams, University of Michigan Medical School
  23. 23. CELLULAR FEATURES OF ANAPLASIAG.D. Abrams, University of Michigan Medical School
  24. 24. PAP SMEAR NORMAL CELLSG.D. Abrams, University of Michigan Medical School
  25. 25. PAP SMEAR MALIGNANT CELLSG.D. Abrams, University of Michigan Medical School
  26. 26. NEOPLASIA IIIGerald D. Abrams
  27. 27. CLINICAL CONSEQUENCES OF NEOPLASMSBENIGN LOCAL MECHANICAL EFFECTS LOCAL COMPLICATIONS SYSTEMIC ENDOCRINE EFFECTSMALIGNANT ALL OF THE ABOVE CANCER CACHEXIA PARANEOPLASTIC SYNDROMES
  28. 28. NOMENCLATURE OF NEOPLASMS•  BASED ON TISSUE OF ORIGIN BENIGN OR MALIGNANT
  29. 29. EPITHELIAL NEOPLASMS•  ADENOMA!!!ADENOCARCINOMA•  PAPILLOMA...PAPILLARY CARCINOMA•  CYSTADENOMA..... CYSTADENOCARCINOMA
  30. 30. ADRENAL CORTICAL ADENOMA Source Undetermined
  31. 31. PANCREAS, ISLET CELL ADENOMADepartment of Pathology, University of Michigan
  32. 32. COLON, ADENOMADepartment of Pathology, University of Michigan
  33. 33. COLON, ADENOMADepartment of Pathology, University of Michigan
  34. 34. Image of sketch of papilloma removed
  35. 35. OROPHARYNX, PAPILLOMA G.D. Abrams, University of Michigan Medical School
  36. 36. OVARY CYSTADENOMASource Undetermined
  37. 37. OVARY CYSTADENOMASource Undetermined
  38. 38. PENIS, SQUAMOUS CELL CARCINOMASource Undetermined
  39. 39. VULVA, SQUAMOUS CELL CARCINOMA Source Undetermined
  40. 40. CERVIX, SQUAMOUS CELL CARCINOMA Source Undetermined
  41. 41. TONGUE, SQUAMOUS CELL CARCINOMA Department of Pathology, University of Michigan
  42. 42. LARYNX, SQUAMOUS CELL CARCINOMA Source Undetermined
  43. 43. ESOPHAGUS, SQUAMOUS CELL CARCINOMA Department of Pathology, University of Michigan
  44. 44. STOMACH, ADENOCARCINOMA Source Undetermined
  45. 45. COLON, ADENOCARCINOMA Department of Pathology, University of Michigan
  46. 46. COLON, ADENOCARCINOMA Source Undetermined
  47. 47. LUNG, SQUAMOUS CELL CARCINOMA Source Undetermined
  48. 48. LUNG, SQUAMOUS CELL CARCINOMA Department of Pathology, University of Michigan
  49. 49. BRONCHUS, SQUAMOUS CELL CARCINOMA Department of Pathology, University of Michigan
  50. 50. BRONCHUS, SQUAMOUS CELL CARCINOMA Department of Pathology, University of Michigan
  51. 51. OVARY CYSTADENOCARCINOMASource Undetermined
  52. 52. OVARY CYSTADENOCARCINOMASource Undetermined
  53. 53. SUPPORTING TISSUE NEOPLASMS•  LIPOMA!!!!LIPOSARCOMA•  CHONDROMA!CHONDROSARCOMA•  FIBROMA!!! FIBROSARCOMA•  OSTEOMA!! OSTEOSARCOMA ETC
  54. 54. COLON, LIPOMADepartment of Pathology, University of Michigan
  55. 55. UTERUS, LEIOMYOMAS Department of Pathology, University of Michigan
  56. 56. BONE, OSTEOSARCOMADepartment of Pathology, University of Michigan
  57. 57. MUSCLE,RHABDOMYOSARCOMADepartment of Pathology, University of Michigan
  58. 58. LYMPHOID / HEMATOPOIETIC NEOPLASMS•  LYMPHOMA(S)•  LEUKEMIA(S)
  59. 59. LYMPHOMASource Undetermined
  60. 60. RETROPERITONEUM, LYMPHOMADepartment of Pathology, University of Michigan
  61. 61. SPLEEN, LYMPHOMADepartment of Pathology, University of Michigan
  62. 62. KIDNEY, LYMPHOMA Department of Pathology, University of Michigan
  63. 63. CNS NEOPLASMS•  MENINGIOMA•  GLIOMA
  64. 64. BRAIN, GLIOMADepartment of Pathology, University of Michigan
  65. 65. NEOPLASMS WITH MIXED DIFFERENTIATION•  CARCINOSARCOMA•  TERATOMA BENIGN MALIGNANT
  66. 66. OVARY, TERATOMADepartment of Pathology, University of Michigan
  67. 67. OVARY, TERATOMADepartment of Pathology, University of Michigan
  68. 68. OVARY, TERATOMADepartment of Pathology, University of Michigan
  69. 69. Additional Source Information for more information see: http://open.umich.edu/wiki/CitationPolicySlide 5: G.D. Abrams, University of Michigan Medical SchoolSlide 6: G.D. Abrams, University of Michigan Medical SchoolSlide 7: G.D. Abrams, University of Michigan Medical SchoolSlide 8: G.D. Abrams, University of Michigan Medical SchoolSlide 9: G.D. Abrams, University of Michigan Medical SchoolSlide 10: G.D. Abrams, University of Michigan Medical SchoolSlide 12: G.D. Abrams, University of Michigan Medical SchoolSlide 13: G.D. Abrams, University of Michigan Medical SchoolSlide 14: G.D. Abrams, University of Michigan Medical SchoolSlide 17: G.D. Abrams, University of Michigan Medical SchoolSlide 18: G.D. Abrams, University of Michigan Medical SchoolSlide 19: G.D. Abrams, University of Michigan Medical SchoolSlide 20: G.D. Abrams, University of Michigan Medical SchoolSlide 21: G.D. Abrams, University of Michigan Medical SchoolSlide 22: G.D. Abrams, University of Michigan Medical SchoolSlide 23: G.D. Abrams, University of Michigan Medical SchoolSlide 24: G.D. Abrams, University of Michigan Medical SchoolSlide 25: G.D. Abrams, University of Michigan Medical SchoolSlide 30: Source UndeterminedSlide 31: Department of Pathology, University of MichiganSlide 32: Department of Pathology, University of MichiganSlide 33: Department of Pathology, University of MichiganSlide 35: G.D. Abrams, University of Michigan Medical SchoolSlide 36: Source UndeterminedSlide 37: Source UndeterminedSlide 38: Source UndeterminedSlide 39: Source UndeterminedSlide 40: Source UndeterminedSlide 41: Department of Pathology, University of MichiganSlide 42: Source UndeterminedSlide 43: Department of Pathology, University of MichiganSlide 44: Source UndeterminedSlide 45: Department of Pathology, University of MichiganSlide 46: Source UndeterminedSlide 47: Source UndeterminedSlide 48: Department of Pathology, University of Michigan
  70. 70. Slide 49: Department of Pathology, University of MichiganSlide 50: Department of Pathology, University of MichiganSlide 51: Source UndeterminedSlide 52: Source UndeterminedSlide 54: Department of Pathology, University of MichiganSlide 55: Department of Pathology, University of MichiganSlide 56: Department of Pathology, University of MichiganSlide 57: Department of Pathology, University of MichiganSlide 59: Source UndeterminedSlide 60: Department of Pathology, University of MichiganSlide 61: Department of Pathology, University of MichiganSlide 62: Department of Pathology, University of MichiganSlide 64: Department of Pathology, University of MichiganSlide 66: Department of Pathology, University of MichiganSlide 67: Department of Pathology, University of MichiganSlide 68: Department of Pathology, University of Michigan


 


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