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Scrotal Masses
UBC Department of Urologic Sciences Lecture Series
Disclaimer:
•This is a lot of information to cover and we
are unlikely to cover it all today
•These slides are to be utilized for your
reference to guide your self study
MCC Objectives
http://mcc.ca/examinations/objectives-overview/
For LMCC Part 1
Objectives applicable to this lecture:
– Scrotal Mass (90-0)
– Scrotal Pain (91-0)
Objectives
Scrotal Mass:
1. Given a patient with a scrotal mass:
1. To list and interpret key clinical findings
2. To list and interpret critical investigations
3. Construct an initial management plan
Causal Conditions:
• Hydrocele
• Varicocele
• Hematocele / hematoma
• Testis malignancy
• Inflammatory / Infectious
2. Recognize testicular torsion
Approach to Scrotal Mass
Approach to Scrotal Mass
PAINFUL
•Epididymitis
•Orchitis
• Hydrocele
• Varicocele
• Spermatocele
• Torsion of Testis
• Torsion of Appendix Testis
• Testis Tumor
Approach to Scrotal Mass
• History
– Pain, onset, firmness, hx of undescended testis,
STD’s, LUTs, urethral discharge
• Physical Exam
– Location of mass (testis, epididymis, scrotum)
– Tenderness
– Transilluminance
• Investigations
– U/A – pyuria with epididymitis / orchitis
– U/S – ++ Sensitive and specific for testicular tumors
Infectious Scrotal Mass
Epididymitis
– Young adults
• often associated with STI, chlamydia
– Older adults
• often non-STI, E Coli.
– Tender, indurated epididymis
• Orchitis
– May be caused by Mumps virus
– Swollen ++ tender testicles, often bilateral
Anatomic Scrotal Mass: Hydrocele
• Hydrocele
• Fluid within tunica vaginalis
• Called “communicating
hydrocoele” if processus
vaginalis is patent
History
• Typically painless
Physical Exam
• Transilluminates
• Cannot palpate testicle
Treatment
• No Rx required unless for
cosmetic reasons or
bothersome size
Anatomic Scrotal Mass
Anatomical Scrotal Mass: Spermatocele
Spermatocele
• Cystic dilatation (aneurysm)
of epididymal tubule
History
• Painless
Physical Exam
• Transilluminates
• Can palpate body of testicle
separate from the mass
Treatment
• No treatment required unless
for cosmetic reasons
Anatomical Scrotal Mass: Varicocele
• Varicocele
Anatomical Scrotal Mass: Varicocele
• Varicocele
– Varicosities of pampiniform plexus
• 90% on left side; seen in 15% of male population
• Associated with male factor infertility but most men with
varicocoeles can expect normal fertility
History
• Typically asymptomatic, cosmetically “bag of worms”
• Increases in size with valsalva or standing position
Physical Exam
• Bag of Spaghetti in scrotum palpating cord
Treatment
• Surgical or angiographic sclerosis
– Results in improvement in semen parameters (number,
motility, morphology) in 70% to 90% of cases
Anatomical: The Acute Scrotum
• Testicular torsion
– Surgical Emergency!!
– Only definitive Diagnosis is Surgical Scrotal
Exploration
– Typically in 12-18yr olds
– 6 hr window prior to irreversible testicular
ischemia
– Associated with ‘Bell Clapper Deformity”
– Detort – “like opening a book”
Anatomic Scrotal Mass: The Acute Scrotum
• Testicular Torsion
Physical Exam
• High riding, horizontal testicle
• Absent cremasteric reflex
• Prehn Sign: relief of pain when supporting the scrotum
– suggests epidiymitis
Investigations
• U/A – R/O pyuria (epidiymitis)
• Doppler U/S only if diagnosis unclear
Treatment
• Surgical detorsion and orchidopexy
Acute Scrotum
• Epididymitis
– Infection of the epididymis
• <35yrs of age – Chlamydia, gonorrhea
• >35yrs of age – E. Coli
History
• Pain, Swelling testicle +/- dysuria +/- fever
Physical Exam
• Indurated, swollen and acutely painful epididymis, +/- erythema
Investigations
• CBC
• U/A
• +/- Doppler US of testis
Treatment
• Antibiotics x4 weeks + NSAIDS, and Ice PRN
Epididymitis
Acute Scrotum: Torsion of Appendix Testis
Torsed Appendix testis
– May mimic Testicular Torsion
Physical Exam
– Blue Dot sign
– Testis may be inflamed/tender, point
tenderness to appendix testis
– Not likely elevated, NO horizontal lie
Investigations
– Doppler US to assess testis perfusion
– U/A
Treatment
– Conservative, symptom management if
confirmed
– Urological assessment.
Approach to Scrotal Mass
PAINFUL
•Epididymitis
•Orchitis
• Hydrocele
• Varicocele
• Spermatocele
• Torsion of Testis
• Torsion of Appendix Testis
• Testis Tumor
Testicular Cancer
• Typically occurs in
young healthy Men.
• Very good cure
rates Even for
Metastatic Disease!
Testicular Cancer
Testicular Cancer
Germ Cell Testicular Cancer
• Seminoma
• Non-Seminoma
– Embryonal Carcinoma
– Teratoma
– Teratocarcinoma (Teratoma +Embryonal
Carcinoma)
– Choriocarcinoma
– Yolk Sac Tumour (typically infants)
Testicular Cancer
Non-Germ Cell Testicular Cancer
• Leydig Cell Tumor
• Sertoli Cell Tumor
Testicular Cancer
Secondary Testicular Cancer
• Lymphoma
• Leukemia
Testicular Cancer
• Presentation
– Typically painless intratesticular mass
discovered on self examination
– Age 15-35
• Albeit some tumor subytpes cluster in infancy and
some at later age (60’s)
Testicular Cancer
• Investigations
– Labs
• B-HCG
– Produced by choriocarcinoma & in some Seminomas
• Alpha-fetoprotein
– Produced by Yolk Sac, Embryonal Carcinoma & Teratocarcinoma
• LDH
– Correlates with tumor volume
– Imaging
• Scrotal U/S
• CT Abdo and Pelvis: assess for retroperitoneal mets
• CXR
• +/- CT Head
Testicular Cancer
• Treatment:
– Radical
Orchiectomy
• ALWAYS Inguinal
approach
• NEVER scrotal
approach
– PLUS…
WAG 2002 UBC Phase IV Urology
Staging
Large retroperitoneal
mass in patient with
right testicular
NSGCT
Lymphatic Spread: RPLND
WAG 2002 UBC Phase IV Urology
Question #1
• 4 causes of scrotal masses or swellings
that are painless
• 3 causes of acutely painful testicle
WAG 2002 UBC Phase IV Urology
Differential Diagnosis of a Scrotal Mass
• hydrocoele
• spermatocoele
• varicocoele
• testicular cancer
• epididymitis
• testicular torsion
• torsion of the testicular appendix
WAG 2002 UBC Phase IV Urology
Acutely Painful Scrotum
In adolescents and young men, with no history of trauma,
the possibilities include:
- Testicular Torsion
- Epididymitis
- Torsion of the Appendix Testis
Testicular torsion and torsion of the appendix testis are
extremely uncommon in older men
WAG 2002 UBC Phase IV Urology
Question #2
Lance Armstrong has noticed a “swelling” in
his remaining testicle.
What features on history or physical exam
suggest a testicular cancer?
WAG 2002 UBC Phase IV Urology
Testicular cancer
• Age 15 – 35 yrs
• History of cryptorchidism or previous testicular
cancer
• Painless
• Does not transilluminate
• Feels hard and irregular
• Constitutional symptoms (weight loss)
WAG 2002 UBC Phase IV Urology
Self - Examination
Self – examination should
be taught to young men
They need to be shown
the difference between the
testicle and the epididymis
They need to report any
hard or suspicious lesions
immediately

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Scrotal masses and Testicular tumors

  • 1. Scrotal Masses UBC Department of Urologic Sciences Lecture Series
  • 2. Disclaimer: •This is a lot of information to cover and we are unlikely to cover it all today •These slides are to be utilized for your reference to guide your self study
  • 3. MCC Objectives http://mcc.ca/examinations/objectives-overview/ For LMCC Part 1 Objectives applicable to this lecture: – Scrotal Mass (90-0) – Scrotal Pain (91-0)
  • 4. Objectives Scrotal Mass: 1. Given a patient with a scrotal mass: 1. To list and interpret key clinical findings 2. To list and interpret critical investigations 3. Construct an initial management plan Causal Conditions: • Hydrocele • Varicocele • Hematocele / hematoma • Testis malignancy • Inflammatory / Infectious 2. Recognize testicular torsion
  • 6. Approach to Scrotal Mass PAINFUL •Epididymitis •Orchitis • Hydrocele • Varicocele • Spermatocele • Torsion of Testis • Torsion of Appendix Testis • Testis Tumor
  • 7. Approach to Scrotal Mass • History – Pain, onset, firmness, hx of undescended testis, STD’s, LUTs, urethral discharge • Physical Exam – Location of mass (testis, epididymis, scrotum) – Tenderness – Transilluminance • Investigations – U/A – pyuria with epididymitis / orchitis – U/S – ++ Sensitive and specific for testicular tumors
  • 8. Infectious Scrotal Mass Epididymitis – Young adults • often associated with STI, chlamydia – Older adults • often non-STI, E Coli. – Tender, indurated epididymis • Orchitis – May be caused by Mumps virus – Swollen ++ tender testicles, often bilateral
  • 9. Anatomic Scrotal Mass: Hydrocele • Hydrocele • Fluid within tunica vaginalis • Called “communicating hydrocoele” if processus vaginalis is patent History • Typically painless Physical Exam • Transilluminates • Cannot palpate testicle Treatment • No Rx required unless for cosmetic reasons or bothersome size
  • 11. Anatomical Scrotal Mass: Spermatocele Spermatocele • Cystic dilatation (aneurysm) of epididymal tubule History • Painless Physical Exam • Transilluminates • Can palpate body of testicle separate from the mass Treatment • No treatment required unless for cosmetic reasons
  • 12. Anatomical Scrotal Mass: Varicocele • Varicocele
  • 13. Anatomical Scrotal Mass: Varicocele • Varicocele – Varicosities of pampiniform plexus • 90% on left side; seen in 15% of male population • Associated with male factor infertility but most men with varicocoeles can expect normal fertility History • Typically asymptomatic, cosmetically “bag of worms” • Increases in size with valsalva or standing position Physical Exam • Bag of Spaghetti in scrotum palpating cord Treatment • Surgical or angiographic sclerosis – Results in improvement in semen parameters (number, motility, morphology) in 70% to 90% of cases
  • 14. Anatomical: The Acute Scrotum • Testicular torsion – Surgical Emergency!! – Only definitive Diagnosis is Surgical Scrotal Exploration – Typically in 12-18yr olds – 6 hr window prior to irreversible testicular ischemia – Associated with ‘Bell Clapper Deformity” – Detort – “like opening a book”
  • 15.
  • 16.
  • 17. Anatomic Scrotal Mass: The Acute Scrotum • Testicular Torsion Physical Exam • High riding, horizontal testicle • Absent cremasteric reflex • Prehn Sign: relief of pain when supporting the scrotum – suggests epidiymitis Investigations • U/A – R/O pyuria (epidiymitis) • Doppler U/S only if diagnosis unclear Treatment • Surgical detorsion and orchidopexy
  • 18. Acute Scrotum • Epididymitis – Infection of the epididymis • <35yrs of age – Chlamydia, gonorrhea • >35yrs of age – E. Coli History • Pain, Swelling testicle +/- dysuria +/- fever Physical Exam • Indurated, swollen and acutely painful epididymis, +/- erythema Investigations • CBC • U/A • +/- Doppler US of testis Treatment • Antibiotics x4 weeks + NSAIDS, and Ice PRN
  • 20. Acute Scrotum: Torsion of Appendix Testis Torsed Appendix testis – May mimic Testicular Torsion Physical Exam – Blue Dot sign – Testis may be inflamed/tender, point tenderness to appendix testis – Not likely elevated, NO horizontal lie Investigations – Doppler US to assess testis perfusion – U/A Treatment – Conservative, symptom management if confirmed – Urological assessment.
  • 21. Approach to Scrotal Mass PAINFUL •Epididymitis •Orchitis • Hydrocele • Varicocele • Spermatocele • Torsion of Testis • Torsion of Appendix Testis • Testis Tumor
  • 22. Testicular Cancer • Typically occurs in young healthy Men. • Very good cure rates Even for Metastatic Disease!
  • 25. Germ Cell Testicular Cancer • Seminoma • Non-Seminoma – Embryonal Carcinoma – Teratoma – Teratocarcinoma (Teratoma +Embryonal Carcinoma) – Choriocarcinoma – Yolk Sac Tumour (typically infants)
  • 27. Non-Germ Cell Testicular Cancer • Leydig Cell Tumor • Sertoli Cell Tumor
  • 29. Secondary Testicular Cancer • Lymphoma • Leukemia
  • 30. Testicular Cancer • Presentation – Typically painless intratesticular mass discovered on self examination – Age 15-35 • Albeit some tumor subytpes cluster in infancy and some at later age (60’s)
  • 31. Testicular Cancer • Investigations – Labs • B-HCG – Produced by choriocarcinoma & in some Seminomas • Alpha-fetoprotein – Produced by Yolk Sac, Embryonal Carcinoma & Teratocarcinoma • LDH – Correlates with tumor volume – Imaging • Scrotal U/S • CT Abdo and Pelvis: assess for retroperitoneal mets • CXR • +/- CT Head
  • 32. Testicular Cancer • Treatment: – Radical Orchiectomy • ALWAYS Inguinal approach • NEVER scrotal approach – PLUS…
  • 33. WAG 2002 UBC Phase IV Urology Staging Large retroperitoneal mass in patient with right testicular NSGCT
  • 35. WAG 2002 UBC Phase IV Urology Question #1 • 4 causes of scrotal masses or swellings that are painless • 3 causes of acutely painful testicle
  • 36. WAG 2002 UBC Phase IV Urology Differential Diagnosis of a Scrotal Mass • hydrocoele • spermatocoele • varicocoele • testicular cancer • epididymitis • testicular torsion • torsion of the testicular appendix
  • 37. WAG 2002 UBC Phase IV Urology Acutely Painful Scrotum In adolescents and young men, with no history of trauma, the possibilities include: - Testicular Torsion - Epididymitis - Torsion of the Appendix Testis Testicular torsion and torsion of the appendix testis are extremely uncommon in older men
  • 38. WAG 2002 UBC Phase IV Urology Question #2 Lance Armstrong has noticed a “swelling” in his remaining testicle. What features on history or physical exam suggest a testicular cancer?
  • 39. WAG 2002 UBC Phase IV Urology Testicular cancer • Age 15 – 35 yrs • History of cryptorchidism or previous testicular cancer • Painless • Does not transilluminate • Feels hard and irregular • Constitutional symptoms (weight loss)
  • 40. WAG 2002 UBC Phase IV Urology Self - Examination Self – examination should be taught to young men They need to be shown the difference between the testicle and the epididymis They need to report any hard or suspicious lesions immediately

Editor's Notes

  1. The Medical Council of Canada list the overall medical objectives expected for understanding when writing the LMCC
  2. There are 2 principal cells of the testicle Leydig Cells (LH stimulate Testosterone and sperm production) and Sertoli Cells Nurture the sperm
  3. Testicular self examination: - teach to distinguish between testicle and epididymis. -report any hard or suspicious lesions immediately
  4. Lymphatic drainage of groin vs scrotum