Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
TITLE                   THE HUMAN ORAL MICROFLORA                   DR.ALI YALDRUM    DATE                            CLAS...
Lecture Objectives                   At the end of this lecture students should be able to                   Describe what...
WHAT IS NORMAL          MICROFLORAFriday, March 23, 2012
‘is the aggregate of microorganism that reside on                   the surface and in deep layers of skin, in the saliva ...
Microflora is a misnomer, Researchers prefer                   “Microbiota”                   In a healthy human, internal ...
human body contains an estimated up of 1014 cells                   only 10% are mammalian cells                   90% are...
so what is oral microflora?                   the microflora existing in the oral cavity is called as                   oral...
FUNCTIONS OF ORAL         CAVITYFriday, March 23, 2012
COMMUNICATION                                 DIGESTIVE                                 SENSORY                           ...
ORAL                   MICROFLORAFriday, March 23, 2012
The presence of nutrients, epithelial debris and                   secretions makes the mouth a favorable habitat for     ...
The oral cavity represents a unique environment                   succession of different ecological situations with      ...
Haemophilus             Corynebacterium                                       Neisseria             S. mitis              ...
at birth the oral cavity is composed solely of the                   soft tissues of the lips, cheeks, soft palate and    ...
Friday, March 23, 2012
Friday, March 23, 2012
other species of streptococci adhere strongly to                   gums and soft tissues                   with the creati...
RELATIONSHIP                   BETWEEN HOST AND                   MICROFLORAFriday, March 23, 2012
does not have a passive relationship                   Beneficial association                   contributes directly and in...
Microbial colonization of all environmentally                   accessible surfaces begins at birth                   Expo...
Microbial flora exists in a harmonious relationship                   with the host                   if this relationship ...
Breakdown is usually associated with                         major changes to the biology of mouth from exogenous         ...
Many oral microorganisms have capacity to                   behave as opportunistic pathogens                   Common cli...
Dental Caries                   ‘is the dissolution of enamel or root surfaces                   (demineralization) by aci...
Periodontal diseasesFriday, March 23, 2012
MICROBIAL          ECOLOGYFriday, March 23, 2012
DISEASE                            SUSCEPTIBLE                 KEY ORAL                                 HOST              ...
SALIVA                                                LIFESTYLE                                                        ORA...
THE ORAL MICROFLORA      AND GENERAL HEALTHFriday, March 23, 2012
Newer evidence is accumulating suggests that                   periodontal diseases have an impact on general             ...
PRETERM LABOR    DIABETES/ GLYCEMIC    ENTER BLOOD STREAM                              CONTROL     PRETERM LOW BIRTH      ...
RESERVOIR FOR                                               HELICOBACTER PYLORI               OPPORTUNISTIC PATHOGENS     ...
References                   Philip D Marsh and Michael V Martin.”Introduction” in Oral Microbiology, 5th Edition. Churchi...
Upcoming SlideShare
Loading in …5
×

The Human Oral Microflora

17,592 views

Published on

  • About 2 years ago, I developed a severe case of vaginal yeast infection that would not let up. The itching, burning and swelling of my labia were simply unbearable. I have purchased several over-the-counter treatments, including Monistat cream to subside the symptoms. While it worked initially, eventually things wore off and left me with an even worse infection than before. The same goes for the antibiotics I took with the advice of my doctor. I felt horrible. After doing some research online, I guessed I had a yeast infection and purchased your program. The results were almost instantaneous. In less than 7 hours, I felt a tremendous relief. Two weeks later and I became completely free from the unbearable vaginal itching, burning, swelling and discharge. Using your methods, I have kept my chronic yeast infection at bay ever since. No more drugs or OTC�s for me. ◆◆◆ https://tinyurl.com/y3flbeje
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here
  • About 2 years ago, I developed a severe case of vaginal yeast infection that would not let up. The itching, burning and swelling of my labia were simply unbearable. I have purchased several over-the-counter treatments, including Monistat cream to subside the symptoms. While it worked initially, eventually things wore off and left me with an even worse infection than before. The same goes for the antibiotics I took with the advice of my doctor. I felt horrible. After doing some research online, I guessed I had a yeast infection and purchased your program. The results were almost instantaneous. In less than 7 hours, I felt a tremendous relief. Two weeks later and I became completely free from the unbearable vaginal itching, burning, swelling and discharge. Using your methods, I have kept my chronic yeast infection at bay ever since. No more drugs or OTC�s for me. ★★★ https://tinyurl.com/y4uu6uch
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here
  • Six weeks into the program and I no longer suffer from the debilitating symptoms that had practically ruined my life. There are no more migraines, no more joint and knee pains, no more menstrual pain, no more rashes on my chest and no more seborrhea on my eyebrows. It is truly a miracle that you have given me... ➤➤ http://ishbv.com/index7/pdf
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here
  • The Yeast Infection No More book has literally saved my life. After years of getting no help from the established "medical profession" and getting sicker and afflicted by pain mood swings and depression, I bought your book and in less than5 weeks my chronic muscle aches and joint pain, caused by my candida yeast infection, have disappeared, and I literally tossed away my cane that I have been using for years. I couldn't believe it, it was nothing short of a miracle. I still can't believe it. Now, months later, the depression has also vanished. I no longer cry with no reason and I feel happier and energized. I am sure the protocols in your book have saved untold thousands of people like me from suffering and pain and "given us our lives back." I will never understand why don�t doctors tell us or investigate more on the subject of candidiasis. Two of my friends, one of them a naturopath had recommended that I try your program. And just like that, I was cured and liberated from years of misery. I have recommended your book to numerous people and all have received a great deal of relief. If only I had been told about it sooner, it would have saved me years of pain and exhaustion. I really tried everything. After 2 months on your program, people say that I look10 years younger, and they are right! Thank you very much for everything you have done for me! ◆◆◆ http://ishbv.com/index7/pdf
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here
  • NICE
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here

The Human Oral Microflora

  1. 1. TITLE THE HUMAN ORAL MICROFLORA DR.ALI YALDRUM DATE CLASS 22-03-12 1ST YEAR B.D.SFriday, March 23, 2012
  2. 2. Lecture Objectives At the end of this lecture students should be able to Describe what is Human Microflora, Oral Microflora Describe the importance of relationship between host and microflora Describe the diverse ecosystem of Oral Microflora Describe the relationship between Oral Health and General HealthFriday, March 23, 2012
  3. 3. WHAT IS NORMAL MICROFLORAFriday, March 23, 2012
  4. 4. ‘is the aggregate of microorganism that reside on the surface and in deep layers of skin, in the saliva and oral mucosa, in the conjuctiva, and in the gastrointestinal tracts.’Friday, March 23, 2012
  5. 5. Microflora is a misnomer, Researchers prefer “Microbiota” In a healthy human, internal tissues are devoid of microorganisms Brain, Blood, Muscles etcFriday, March 23, 2012
  6. 6. human body contains an estimated up of 1014 cells only 10% are mammalian cells 90% are resident microbiotaFriday, March 23, 2012
  7. 7. so what is oral microflora? the microflora existing in the oral cavity is called as oral microflora.Friday, March 23, 2012
  8. 8. FUNCTIONS OF ORAL CAVITYFriday, March 23, 2012
  9. 9. COMMUNICATION DIGESTIVE SENSORY GENERAL HEALTH FIG.1Friday, March 23, 2012
  10. 10. ORAL MICROFLORAFriday, March 23, 2012
  11. 11. The presence of nutrients, epithelial debris and secretions makes the mouth a favorable habitat for a variety of microorganisms Streptococcus Actinomyces Prevotella FusobacteriumFriday, March 23, 2012
  12. 12. The oral cavity represents a unique environment succession of different ecological situations with age corresponds with the changes in the composition of normal floraFriday, March 23, 2012
  13. 13. Haemophilus Corynebacterium Neisseria S. mitis S. mitis Staphylococcus S. pneumoniae Streptococcus Actinomyces S. pyogenes Fusobacterium S. salivarius Porphyromonas Candida Streptococcus FIG.2 SITE SPECIFICITY OF MICROBIAL ADHERENCE & COLONIZATIONFriday, March 23, 2012
  14. 14. at birth the oral cavity is composed solely of the soft tissues of the lips, cheeks, soft palate and tongue. kept moist by the salivary secretionsFriday, March 23, 2012
  15. 15. Friday, March 23, 2012
  16. 16. Friday, March 23, 2012
  17. 17. other species of streptococci adhere strongly to gums and soft tissues with the creation of gingival crevice area increases the habitat for the variety of anaerobic species complexity continues to increase with timeFriday, March 23, 2012
  18. 18. RELATIONSHIP BETWEEN HOST AND MICROFLORAFriday, March 23, 2012
  19. 19. does not have a passive relationship Beneficial association contributes directly and indirectly to the normal development physiology nutrition defenseFriday, March 23, 2012
  20. 20. Microbial colonization of all environmentally accessible surfaces begins at birth Exposed to wide range of microorganisms Each surface is suitable for colonization by a proportion of these microbes Acquisition, selection and natural development of diverse but characteristic microfloraFriday, March 23, 2012
  21. 21. Microbial flora exists in a harmonious relationship with the host if this relationship breaks down, disease can occur in mouth this relationship is more prone to breakdown than other parts of the bodyFriday, March 23, 2012
  22. 22. Breakdown is usually associated with major changes to the biology of mouth from exogenous sources presence of the microorganisms at sites not normally accessible to them such microorganisms are termed as ‘opportunistic pathogens’Friday, March 23, 2012
  23. 23. Many oral microorganisms have capacity to behave as opportunistic pathogens Common clinical manifestations of oral microflora imbalance are Dental Caries Periodontal diseasesFriday, March 23, 2012
  24. 24. Dental Caries ‘is the dissolution of enamel or root surfaces (demineralization) by acid produced primarily by fermentation of carbohydrates in the diet by bacteria colonizing the tooth surface (dental plaque).’Friday, March 23, 2012
  25. 25. Periodontal diseasesFriday, March 23, 2012
  26. 26. MICROBIAL ECOLOGYFriday, March 23, 2012
  27. 27. DISEASE SUSCEPTIBLE KEY ORAL HOST MICROORGANISM ENVIRONMENTAL TRIGGER THE INTERRELATIONSHIPS THAT LEAD TO ORAL DISEASE.Friday, March 23, 2012
  28. 28. SALIVA LIFESTYLE ORAL MICROBIAL ECOLOGY HOST MICROFLORA DEFENSES INTER-RELATIONSHIPS THAT INFLUENCE THE MICROBIAL ECOLOGY OF THE MOUTH IN HEALTH & DISEASEFriday, March 23, 2012
  29. 29. THE ORAL MICROFLORA AND GENERAL HEALTHFriday, March 23, 2012
  30. 30. Newer evidence is accumulating suggests that periodontal diseases have an impact on general health.Friday, March 23, 2012
  31. 31. PRETERM LABOR DIABETES/ GLYCEMIC ENTER BLOOD STREAM CONTROL PRETERM LOW BIRTH TRANSIENT BACTERAEMIAS WEIGHT ATHEROSCLEROSIS CORONARY HEART DISEASEFriday, March 23, 2012
  32. 32. RESERVOIR FOR HELICOBACTER PYLORI OPPORTUNISTIC PATHOGENS (GASTROESOPHAGEAL REFLUX) ASPIRATION OF THESE PATHOGENS INTO LOWER RESPIRATORY TRACT CAN LEAD TO SERIOUS LUNG DETECTED IN DENTAL PLAQUE INFECTION LINKED WITH DEEP PERIODONTAL POCKETS CHRONIC GASTRITIS & STOMACH ULCERSFriday, March 23, 2012
  33. 33. References Philip D Marsh and Michael V Martin.”Introduction” in Oral Microbiology, 5th Edition. Churchil Livingstone, 2009, pp 1-7. Todar’s Online Textbook of Bacteriology, Internet: http://textbookofbacteriology.net/normalflora.html [Mar 3, 2012] Fig 1. http://www.shutterstock.com/pic-51438295/stock-vector-oral-cavity.html Fig 2. “Complex Communities” in Oral Microbiology at a Glance, Wiley-Blackwell, 2010. pp 28.Friday, March 23, 2012

×