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iExplore: A provenance-based application for
           exploring biomedical knowledge

Vinh Nguyen, Olivier Bodenreider, ...
Why iExplore?
• Biomedical Knowledge Repository (BKR)
     – Developed at NLM
     – Integrating various knowledge sources...
How to explore BKR?
   • Large knowledge base
            – 71 milliion triples in the BKR Instances
            – 4 milli...
Approach
   • Graph visualization
   • Interactive exploration
   • Explore either PubMed or UMLS




6/28/2012           ...
Demo
    iExplore is available at
    http://knoesis.wright.edu/iExplore/iExplore.html




6/28/2012                      ...
Technologies
• Semantic Web
      – RDF, SPARQL standards
      – Virtuoso triple store
• iExplore development
      – Cli...
Q&A




6/28/2012         7
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iExplore: A provenance-based application for exploring biomedical knowledge

  1. 1. iExplore: A provenance-based application for exploring biomedical knowledge Vinh Nguyen, Olivier Bodenreider, Thomas Rindflesch, Amit Sheth
  2. 2. Why iExplore? • Biomedical Knowledge Repository (BKR) – Developed at NLM – Integrating various knowledge sources – Represented in RDF 6/28/2012 2
  3. 3. How to explore BKR? • Large knowledge base – 71 milliion triples in the BKR Instances – 4 million triples in the BKR Schema • Modeled from – 2 million Metathesaurus concepts – Semantic predications extracted from PubMed abstracts (2000-2009) by SemRep • Broad domain coverage 6/28/2012 3
  4. 4. Approach • Graph visualization • Interactive exploration • Explore either PubMed or UMLS 6/28/2012 4
  5. 5. Demo iExplore is available at http://knoesis.wright.edu/iExplore/iExplore.html 6/28/2012 5
  6. 6. Technologies • Semantic Web – RDF, SPARQL standards – Virtuoso triple store • iExplore development – Client side: Adobe Flex – Server side: Java 6/28/2012 6
  7. 7. Q&A 6/28/2012 7

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