Phytosome® a novel drug delivery system based herbal formulation


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Phytosome® a novel drug delivery system based herbal formulation

  1. 1. Presented byAnirudh Padiyar
  2. 2. INNOVATOR COMPANY Indena Phytosome® U.S. Patent # 4,764,508worlds leading company in the identification,development and production of active principlesderived from plants, for use in pharmaceutical, health-food and personal care industy.
  3. 3. Phytosome vs Liposome.
  4. 4. Advantages of phytosome Better bioavailability. Reduced dose. Hepatoprotective synergistic effect. Better stability profile. Nutritional benefit.
  5. 5. FormulationPatented Procedure.Phytosome® U.S. Patent # 4,764,508
  6. 6. Siliphos® Bioavailable silybin Plasma levels of total silybin after oral Silipide® and silybin in rats, where Silipide® (200mg/kg as silybin) and silybin (200 mg/kg) were administered by gavage as aqueoussuspensions to 6 male rats.
  7. 7. Ginkgoselect® Phytosome vs Ginkgo bilobaextractFifteen healthy volunteers two groups and administeredrespectively 160 mg of free formulation of GBE and160 mg of Ginkgoselect® Phytosome®
  8. 8. Meriva® vs Curcumin In comparative study in humans the overall curcuminoid absorption was about 29-fold higher.
  9. 9. Greenselect® Phytosome vs green tea extract
  10. 10. Tablet formulation with Phytosome® complex Leucoselect® Phytosome® 100.0 mg Soy polysaccharides 138.0 mg Corn starch 100.0 mg Silicon dioxide 6.0 mg Talc 3.0 mg Magnesium stearate 3.0 mg
  11. 11. Hard gelatin capsule formulation withPhytosome® complex Ginkgoselect® Phytosome® 180.0 mg Dicalcium phosphate dihydrate 196.0 mg microcrystalline cellulose 47.0 mg Croscarmellose sodium 23.0 mg Talc 2.0 mg Magnesium stearate 2.0 mg
  12. 12. Conclusion All that man needs for health and healing hasbeen provided by God in nature, the challenge ofscience is to find it. Novel drug delivery systems of herbal drugs have apotential future for enhancing the activity andovercoming problems associated with plantmedicines.
  13. 13. THANK YOU