• “Intrinsic neural timescale” — How fast/slow the
autocorrelation of neural activity (at a given location /
• e.g. frontal, parietal > sensory areas (human, macaque)
• High-functioning adults with autism
• Known for: impaired global integration of diverse info,
over-enhancement of individual inputs
• Dependence on where in the brain?
• Not about the networks
• Relevance to cognitive functions?
• Previous literature: large timescale ~ robust sensory
perception, stable memory processing, accurate
• Resting-state fMRI
• Also validation by two other data sets (ETH Zürich data and Indiana University data)
• Large GMV → more repetitive neural activity patterns → larger
autocorrelation (larger intrinsic timescale) ?
• Computational studies?
• Likewise, large intrinsic timescales (and temporal receptive
windows) imply high ability of local brain areas to pool, normalise
and complete information.
• Again, computational accounts?
• Speed of neural dynamics? Rather corresponds to low intrinsic
• Role of local recurrent connectivity? Inh? Exc?
• Low time resolution of data
• Watanabe, Rees, Masuda, eLife, 8, e42556 (2019).
• Insight Article by Gollo, eLife, 8, e45089 (2019).