Starling Forces: Interstitial Pressures <ul><li>Interstitial fluid pressure  in most tissues is  – 3.  But encapsulated or...
Lymphatic System <ul><li>An accessory route by which  fluid and protein can flow from  interstitial spaces to the blood </...
 
 
Determinants of Lymph Flow <ul><li>The degree of activity of the lymphatic pump </li></ul><ul><ul><ul><li>smooth muscle fi...
Determinants of Lymph Flow Interstitial fluid hydrostatic pressure Lymph Flow Figure 16-9; Guyton and Hall Figure 16-10; G...
 
 
 
 
 
 
 
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Lymphatics (Abbrev) Student Notes

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Lymphatics (Abbrev) Student Notes

  1. 3. Starling Forces: Interstitial Pressures <ul><li>Interstitial fluid pressure in most tissues is – 3. But encapsulated organs can have positive interstitial pressures (+5 to +10 mmHg). </li></ul><ul><li>Negative interstitial fluid pressure is caused by pumping of lymphatic system. </li></ul><ul><li>Two kinds of valves: (1) the walls of the lymph capillaries allow absorption of the tissue fluid through valve-like edge structures; and (2) the vessels have valves (similar to veins in limbs) are helped by both skeletal muscle action and also pulsing lymph vessel smooth muscles . </li></ul>
  2. 4. Lymphatic System <ul><li>An accessory route by which fluid and protein can flow from interstitial spaces to the blood </li></ul><ul><li>Important in preventing edema </li></ul><ul><li>Lymph is derived from interstitial </li></ul><ul><li>fluid that flows into the lymphatics </li></ul><ul><li>Major route for absorption of nutrients from the GI tract </li></ul><ul><li>Plays important role in the immune system </li></ul>
  3. 7. Determinants of Lymph Flow <ul><li>The degree of activity of the lymphatic pump </li></ul><ul><ul><ul><li>smooth muscle filaments in lymph vessel cause them to contract </li></ul></ul></ul><ul><ul><ul><li>external compression from surrounding skeletal muscles also contributes to lymphatic pumping </li></ul></ul></ul>Figure 16-11; Guyton and Hall
  4. 8. Determinants of Lymph Flow Interstitial fluid hydrostatic pressure Lymph Flow Figure 16-9; Guyton and Hall Figure 16-10; Guyton and Hall

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