Nucleic acids
pp 80 - 84
Nucleic Acids
Nucleic acids are used for:
 maintaining genetic continuity
 delivering information for protein synthesis
...
Nucleic Acids
DNA RNA
 located in the nucleus
 double-stranded, double
helix structure
 stable molecule
 mainly found ...
Nucleotides
The basic subunit of nucleic acids is a nucleotide.
Three components:
1. phosphate
2. pentose sugar
3. nitroge...
Pentose Sugar
1’
2’3’
4’
5’
1’
2’3’
4’
5’
Nitrogenous Bases
purines
pyrimidines
DNA/RNA DNA/RNA
DNA/RNA RNA DNA
Nucleic Acid
Phosphodiester bond formed
between
1. pentose sugar OH group
of one nucleotide
2. phosphate group of
another ...
Nucleic Acid
Linking nucleotides
together produces a
single-strand of DNA
The phosphate and
deoxyribose form the
DNA’s “ba...
Complimentary Base Pairing
Nitrogenous bases can
“stick” to one another via
hydrogen bonding.
Complimentary base pairs:
Ad...
Nucleic Acid
Complimentary base pairing
results in double-stranded
DNA.
Both DNA strands run
antiparallel to each other
(o...
Complimentary Base Pairing
The two antiparallel
strands coil together to
form a double helix.
Double Helix
Overview
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Tang 03d macromolecules-nucleic acids-2010 update

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Tang 03d macromolecules-nucleic acids-2010 update

  1. 1. Nucleic acids pp 80 - 84
  2. 2. Nucleic Acids Nucleic acids are used for:  maintaining genetic continuity  delivering information for protein synthesis  energy molecule (ATP – adenosine triphosphate) Two major nucleic acid polymers: 1. DNA – deoxyribonucleic acid 2. RNA – ribonucleic acid
  3. 3. Nucleic Acids DNA RNA  located in the nucleus  double-stranded, double helix structure  stable molecule  mainly found in cytoplasm  single-stranded structure  less stable molecule
  4. 4. Nucleotides The basic subunit of nucleic acids is a nucleotide. Three components: 1. phosphate 2. pentose sugar 3. nitrogenous base
  5. 5. Pentose Sugar 1’ 2’3’ 4’ 5’ 1’ 2’3’ 4’ 5’
  6. 6. Nitrogenous Bases purines pyrimidines DNA/RNA DNA/RNA DNA/RNA RNA DNA
  7. 7. Nucleic Acid Phosphodiester bond formed between 1. pentose sugar OH group of one nucleotide 2. phosphate group of another nucleotide NOTE: 3’-carbon and 5’- carbon atoms are linked by a phosphate group
  8. 8. Nucleic Acid Linking nucleotides together produces a single-strand of DNA The phosphate and deoxyribose form the DNA’s “backbone” backbone nitrogenous bases
  9. 9. Complimentary Base Pairing Nitrogenous bases can “stick” to one another via hydrogen bonding. Complimentary base pairs: Adenine  Thymine (AT) - 2 hydrogen bonds Guanine  Cytosine (GC) - 3 hydrogen bonds
  10. 10. Nucleic Acid Complimentary base pairing results in double-stranded DNA. Both DNA strands run antiparallel to each other (oriented in opposite directions). One strand is from 5’3’, while the other strand is from 3’5’. antiparallelstrand 5’ 3’ 3’ 5’
  11. 11. Complimentary Base Pairing The two antiparallel strands coil together to form a double helix.
  12. 12. Double Helix
  13. 13. Overview

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