Protein Structure What are proteins?
Protein Structure <ul><li>Lesson Objectives </li></ul><ul><li>To describe primary and secondary protein structures </li></...
Protein Structure <ul><li>Proteins are made of amino acids joined together.  The type, number and order of these amino aci...
Primary Structure <ul><li>There are twenty different amino acids that can be found in proteins.  </li></ul><ul><li>These a...
Primary Structure <ul><li>Biochemists abbreviate the amino acids to three letter codes.  A peptide chain can therefore be ...
Peptide Bonds Taken from Biology pages, langara College, Vancover, Canada
Secondary Structure <ul><li>A polypeptide chain will naturally fold into two main structures; </li></ul><ul><li>Alpha Heli...
Alpha Helix ( α -helix)
Beta pleated sheet
Summary <ul><li>Proteins are composed of amino acids joined together to form a polypeptide chain </li></ul><ul><li>The num...
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Proteinstructure1

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Proteinstructure1

  1. 1. Protein Structure What are proteins?
  2. 2. Protein Structure <ul><li>Lesson Objectives </li></ul><ul><li>To describe primary and secondary protein structures </li></ul><ul><li>To describe the structure and formation of an alpha helix and a beta pleated sheet </li></ul>
  3. 3. Protein Structure <ul><li>Proteins are made of amino acids joined together. The type, number and order of these amino acids will determine the initial structure of the protein. </li></ul><ul><li>The protein will then fold into a specific shape due to the bond angles and intramolecular bonding that occurs. </li></ul><ul><li>Some proteins will also associate with other chemical species e.g. Fe ions. </li></ul>
  4. 4. Primary Structure <ul><li>There are twenty different amino acids that can be found in proteins. </li></ul><ul><li>These amino acids join together to form a polypeptide chain. </li></ul><ul><li>The order and number of amino acids in the chain is known as the Primary structure of a protein. </li></ul>
  5. 5. Primary Structure <ul><li>Biochemists abbreviate the amino acids to three letter codes. A peptide chain can therefore be described as: </li></ul><ul><li>Gly-Phe-Lys-Gln-Asp-Gly-Leu-Leu-Ala-Gly-Ala-Met </li></ul><ul><li>This peptide chain consists of 12 amino acids of 8 different types. </li></ul>
  6. 6. Peptide Bonds Taken from Biology pages, langara College, Vancover, Canada
  7. 7. Secondary Structure <ul><li>A polypeptide chain will naturally fold into two main structures; </li></ul><ul><li>Alpha Helices and Beta Pleated Sheets </li></ul>
  8. 8. Alpha Helix ( α -helix)
  9. 9. Beta pleated sheet
  10. 10. Summary <ul><li>Proteins are composed of amino acids joined together to form a polypeptide chain </li></ul><ul><li>The number, type and order of amino acids in the chain is known as the primary structure. </li></ul><ul><li>The polypeptide chain folds to produce secondary structures called alpha helices and beta pleated sheets. </li></ul>

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