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Treating Anxiety and Depression


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Treating Anxiety and Depression

  1. 1. Morwenna Given, B.A., M.A.(Oxon), BSc, mOHA, BHG, RHMedical
  2. 2. We combine the art of holistic treatment andthe science of plant healing properties to helppeople achieve optimum healthWe are specialists in the use of medicinal plantsand their ability to resolve diseaseOur practice is based on internationallyaccepted scientific evidence (including McGill and McMaster)We have the ability to treat in combination withorthodox drugs
  3. 3. 6 years of training in University, Hospital andClinic settingsTraining includes the Western bio-chemicalphysician modelAdditional training in pharmacology,biochemistry, phytochemistry and phytotherapyto treat medical conditions with plant medicineand to work alongside conventional medicine
  4. 4. Plant medicine has been shown to be safe andunlikely to have unwanted side effectsMedicinal plants have been shown in tests andtrials to be highly effective and in some casesbetter than pharmaceutical drugsHerbal medicine is derived from the flowers,fruits, leaves, stems, and roots of plants tomaintain a complex synergy of natural organicchemical compounds
  5. 5. Depressed mood for most of the day, every day,for 2 weeks, anhedonia, plus 3 or more of: Change in appetite/weight Agitation Change in sleep patterns Anxiety Feelings of worthlessness Decreased ability to concentrate Recurrent thoughts of death or suicide
  6. 6. Phobic experiences e.g. AgoraphobiaPanic experiences e.g. Escape AttacksGeneral anxiety disorders which involveabnormal levels of agitation and/or worry& in association with other diseases
  7. 7. Abnormal Biochemistry The causes of major depressive disorders have not been clearly defined It involves disturbance in neurotransmitters and hormones in the central nervous systemNutritional DeficienciesNeurotransmitter problemsHormonal imbalancesReaction to lifestyle/eventsOther somatic causes e.g. Multiple Sclerosis, Menopause
  8. 8. Men are from Mars, Women are from Venus Women – 3 forms of Estrogens, Progesterone, and other Endocrine hormones Men – Testosterone, Pregnenolone (DHEA) (DHT) Change in Age - for both men and women
  9. 9. A substance produced in the body from a gland(brain/thyroid)Carried to other parts of the body to elicit aresponse from a tissue structure or chemicalreceptorHormones are found all over the body
  10. 10. Progesterone has a Sedative effect (calms)Estrogen has an Anxiolytic effect (anxiety)High progesterone converts to high Androgenswhich make people more aggressiveLow progesterone results in lack of drive
  11. 11. Thyroid This organ/gland is a major player in depression and anxiety Ontario has endemic sub-clinical hypothyroidism The conventional doctor has no drugs for this problem Ontario has sub-clinical levels of Vitamin D
  12. 12. The body has a close physiological relationshipbetween the endocrine and nervous systemsOur emotions in the brain create peptideswhich affect hormones – peptides are chemicalmessengersRegulated by horizontal, vertical and diagonalaxes from the brain to the body
  13. 13. The Hypothalamus – Composer The Pituitary – Conductor The Endocrine Glands – Musician The Cells of the Glands – Instruments The Hormones – Musical Notes The Receptors - AudienceWhen one aspect does not function normally, the body tries to adjust.An unsuccessful adjustment leads to anxiety and/or depression.
  14. 14. Stress is the body’s response to any demand.How we deal with it can be good or bad. Hans Seyle (Canadian) defined GAS (General Adaptation Syndrome) 3 stage process: Alarm Resistance Exhaustion Stress is cumulative and over time exhausts the adrenal glands Artists are a small business / huge stress burden
  15. 15. NO clear data but @30- 20% of the generalpopulation.Functional disorders @ 5% of the populationwith a known high proportion of artists “November 10, 2011 — Creative individuals have a disproportionately higher rate ofmental illness, including schizophrenia and bipolar disorder, and they and theirrelatives are more likely to work in artistic and scientific occupations, according tonew research published in the November 2011 issue of the British Journal ofPsychiatry.” MedscapeResearch focusses on sub-groups & the how butnot the why
  16. 16. RespiratoryGIT Genito urinary General BodyCVS Tension Insomnia
  17. 17. ParacelusThe nervous system has 2 complimentaryhalves:Parasympathetic – normally dominant Associated with rest, digestion, we are naturally lazy!Sympathetic – alarm state Associated with adrenaline, raised heartbeat, digestion stops Continual activation leads to adrenal stress
  18. 18. Based on an internationally recognized scale(DSM-1V-TR)Resulting in a differentiation between afunctional disorder versus a general anxietydisorder – schizophrenia vs. post nataldepressionFunctional disorders involve the psyche (mind)General anxiety disorders are somatic (body)
  19. 19. Usually involve drugs e.g. SSRIs, MAOIs,tricyclic antidepressants, and nor adrenergicselected re-uptake inhibitorsBUT… They have about 5% efficacy They do not address the causes They have serious side effects – addiction et al
  20. 20. The body only ‘the mind and the body cannot beseparated’ (Socrates) treat the CAUSE balancing the regulation ofparasympathetic/sympathetic nervous system correct the balance of hormonal activity –centrally and peripherally ensure the body drains and eliminates properlywith good blood flow to the tissues TREATMENTS are INDIVIDUAL.
  21. 21. Adaptogens – ginsengs, withania, schizandraProvide an increase in the body’s non-specific resistance to damaging man madefactors and related illnesses Nervines – valerian, St. john’s wort, skull cap,rose and so on depending on the condition Anti Spasmodic – snowball – relaxes smoothmuscle Bitters – chamomile, century – anti anxiolyticand stimulates elimination
  22. 22. High in Vitamin CEffective in anxietyassociated – meno-pause, diabetes,bereavement
  23. 23. Arctic Rose - Adaptogen Adaptogens normalise the body via the HPA They support the body through periods ofextensive stress without any negative side effects Long / short term use Phytomedicine. 2010 Jun;17(7):481-93. Rosenroot (Rhodiola rosea): traditional use, chemical composition,pharmacology and clinical efficacy. Panossian A, et al The adaptogenic, cardiopulmonary protective, and central nervous system activities of Rhodiola rosea have beenattributed primarily to its ability to influence levels and activity of monoamines and opioid peptides such as beta-endorphins. (Altern Med Rev 2001;6(3):293-302) Ecdysteroids – ability to correct DNA – extensive Russian & Scandinavian research
  24. 24. Adaptogen Has the ability to raise thyroid hormones to normal levelsin conjunction with other plants It also works thru the HPA and balances estrogen Increases white cells Normalizes hemoglobin Significant glucocorticoid effects Anti mitotic effect in metaphase cells Sedative, hypnotic Bacteriostatic
  25. 25. Nervine Wonderful multi purpose plant. Anti depressant, anti cancer, anti bacterial, antiviral, balances serotonin/dopamine Hormone balancer Better than conventional SSRI’s 2009 confirmation for safe use in severe depression and moderate depression in 2005; 2009confirmation of year long use safe and effective in mild to moderate depression. 2009 double blind trial confirming use in perimenopausal women in controlling hot flushes andbetter sleep.( in Quebec!!) 2009 Meta analysis showed Hypericum to be as effective as SSRIs with less adverse effects
  26. 26. Nervines Anti anxiolytic for the GABA pathways, helps withinsomnia2008 in vivo confirmed mechanism of gaba pathways of anxiolytic effects, effectsimilar to diazepam. Phytother Res. 2011 Jun;25(6):838-43. Affects the HPA, relaxes the arteries, acts on Gaba andserotonin pathways Calms/balances hormones, helps with insomnia, antiviral, anti bacterial, acts on the thyroid peripherallyConfirmation of vaso relaxant effect on heart endothelium 2008.
  27. 27. Plants work better together !!Fitoterapia. 2011 Apr;82(3):474-80.Pharmacological studies in anherbal drug combination of St.Johns Wort (Hypericumperforatum) and Passion Flower(Passiflora incarnata): in vitro andin vivo evidence of synergybetween Hypericum and Passiflorain antidepressant pharmacologicalmodels. Fiebich BL et al .Department of Psychiatry,University of Freiburg MedicalSchool,
  28. 28. Bitters The herbal family of bitters combine manyactions in one safe plant – anti anxiolytic, antibacterial, anti viral, cross the blood brain barrier,hepatoprotective, sedative, HPA regulator, etc A Medical Herbalist treats the whole body - theissue of elimination is critical for normal function Bitters support/stimulate/correct elimination
  29. 29. B6, B12, Folic Acid – HomocysteineThiaminOmega 3 fatty acids EPA deficienciesIron DeficiencyZinc DeficiencyMagnesium DeficiencyLow vitamin D – You are my sunshine!
  30. 30. Chocolate!! Low carb diet. Krikorian R, et al. Dietary ketosis enhances memory in mildcognitive impairment. Neurobiol Aging 2 December 2010 Omega 3 fats Food additives Many symptoms masked the cause – dietaryimbalances
  31. 31. Relaxation, Yoga, Visualization, MeditationGardening ‘smell the roses’Recognize strengths and limitationsPsychotherapy
  32. 32. The compounds that I give do not come fromover the counter productsOnly registered herbalists may compound anduse these products which are made under thesame regulations as drugsIf you self treat, you may cause further problemsPlease do not confuse these plants/medicine withsupplements which by law cannot have medicallytherapeutic effect.
  33. 33. For a complete copy of all references used in thispresentation (@15 pages), please email:mrsmg@sympatico.caPlease note that many peer reviewed articles arebased on supplements not whole plant extracts e.g.Canmat 2009All reference material is available onPubmed/Science Direct
  34. 34. THANK YOU Morwenna GivenRegistered Medical Herbalist