23/09/2012    MULTIPLE SCLEROSISA SEMINAR FOR THE MS SOCIETY OF           TORONTO                    BY      MORWENNA GIVE...
2                     23/09/2012                 WHO AM I?Iam a medical herbalist, trained in University, Hospital and cl...
3                     23/09/2012           MS : causes Genetic   Unknown environmental Traditional    aetiology. Most r...
4                     23/09/2012                       BUT In   my practise Careful  case history taking has universally...
5                                23/09/2012       Current Research on             Causes It  is now being admitting that ...
6                   23/09/2012        Environmental –       diseases of excess MS has long been associated with northern ...
7                     23/09/2012       Pathology –  simplistically speaking The  initial process of MS starts with inflam...
8                     23/09/2012CONSEQUENCES OF PATH This results in acute and chronic plaque formation  within the CNS, ...
9                      23/09/2012    RESULTS OFPATHOLOGY PROCESS   Removing the myelin sheath from neuronal fibres    mea...
10                   23/09/2012               THE EFFECT Is   like a plug which is not earthed Resulting  in a blown fus...
11                     23/09/2012 MS SYMPTOMS – some Optic  neuritis, facial palsy Relapsing and remitting sensory sympt...
12                         23/09/2012  Conventional approach Diagnosis: By exclusion Imaging & CSF examination Drugs:...
13                      23/09/2012      SYMPTOM/ DRUGS Spasticity– baclofen Ataxia - clonazepam Pain - gabapentin Urin...
14                                  23/09/2012                         SURGERY Does        not treat the causeVenous angi...
15                    23/09/2012       WHAT IS A MEDICAL HERBALIST A person   who treats medical disease  ‘wholistically’...
16     23/09/2012HOW AM I TRAINED?                        ©
17              23/09/2012          PHILOSOPY MEDICAL HERBALISTS    LOOK AT THE  PATIENT AS A WHOLE NOT AS A SPECIFIC  CO...
18                     23/09/2012        HOW DO I TREAT?I   review all aspects of the health of the person Diet, exercis...
19                     23/09/2012         HOW DO I TREAT?   You may remember there was no mention of    exercise or diet ...
20                             23/09/2012                                   Diet Linoleic   acid levels are abnormally lo...
21                            23/09/2012                                 DIET Gluten      intolerance may be a factor Hy...
22                      23/09/2012     Vitamin D Deficiency Ontario is well known for its lack of vitamin D in  the popul...
23                             23/09/2012         Is Lack of Vitamin D             a co-factor? Yes,    in making MS symp...
24            23/09/2012                                      Sugar   Like all diseases of excess sugar plays a key role ...
25                              23/09/2012                           Exercise Exercise       – improves brain function M...
26                     23/09/2012            Review existing             medications   Statins - Inhibits the formation o...
27                   23/09/2012   Review MS symptomsas expressed by the patientSuch as: Sleep issues Excretion issues S...
28                    23/09/2012              Sub clinical            hypothyroidism Iodine,   selenium, zinc    Directl...
29                   23/09/2012     Review the Patient’s      other symptoms Spasticity Movement Cognitive   functionAn...
30                    23/09/2012                    PlantsI  choose the plants that offer the medical  therapeutics that ...
31                                23/09/2012            Curcuma Longa &            Scentella Asiatica   Recent Pat CNS Dr...
32                      23/09/2012                   Plants Withania – adaptogens Astragalas – anti inflammatories Nerv...
33   23/09/2012
34                   23/09/2012      HOW THEY WORK Plantshave many chemicals in them which work  at many levels of the bi...
35                             23/09/2012           Medical marijuanaI    am not a supporter of the use of this plant as ...
36     23/09/2012VIBURNUM OPULUS -      BARK                        ©
37                    23/09/2012   ANTI SPASMOLYTICS Thereare a number of plants which provide anti spasmolytic actions w...
38                   23/09/2012          SUPPLEMENTS There  are some specific supplements beneficial in  MS such as pure ...
39                       23/09/2012                      CAUTIONS   PLEASE NOTE: IT IS ADVISED, THAT ANY PLANTS    MENTIO...
40                    23/09/2012              References www.   Pubmed, Science directI have a full list of references f...
41          23/09/2012  THANK YOU  MORWENNA GIVENWWW.MEDICUSHERBIS.COM       © 2012
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Multiple sclrosis

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Multiple sclrosis, natural remedies, herbs, herbalist, alternative therapy, alternative treatments

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Multiple sclrosis

  1. 1. 23/09/2012 MULTIPLE SCLEROSISA SEMINAR FOR THE MS SOCIETY OF TORONTO BY MORWENNA GIVEN BA MA (OXON) BSC M.OHA BHG RH MEDICAL HERBALIST 1 ©© SEPTEMBER 2012 ©
  2. 2. 2 23/09/2012 WHO AM I?Iam a medical herbalist, trained in University, Hospital and clinics With a practise in downtown Toronto focussing on Chronicauto immune diseases including MS, Cancer, Alzheimers, diabetes, and womens’ issues ©
  3. 3. 3 23/09/2012 MS : causes Genetic Unknown environmental Traditional aetiology. Most research has been concentrated on genetic factors as patenting drugs in this area is much easier since the Americans patented part of the human genome ©
  4. 4. 4 23/09/2012 BUT In my practise Careful case history taking has universally shown the possible cause is viral infection plus deficient nutrients leading to an immunocompromise in the patient. ©
  5. 5. 5 23/09/2012 Current Research on Causes It is now being admitting that there is considerable evidence to show the initiator of MS is an infection This maybe viral or bacterial Trigger, pathogen or bystander: the complex nexus linking Epstein Barr virus and multiple sclerosis Owens GP et al Mult Scler 2012 June 8 Is the treatment of multiple sclerosis headed in the wrong direction? Kadoch MA Can J NeuroSci 2012 May 39(3)405 Active intrathecal herpes simplex virus type 1 and human herpes virus -6 infection at the onset of multiple sclerosis. Ferro MT et al J Neurovirol 2012 May 19 epub ahead of print. ©
  6. 6. 6 23/09/2012 Environmental – diseases of excess MS has long been associated with northern climes and temperate zones…..i.e. the western diet heavy on meat/potatoes/grains As the BRIC countries consume western processed diets in favour of their own high vegetable diets the incidence rate for MS is rising. ©
  7. 7. 7 23/09/2012 Pathology – simplistically speaking The initial process of MS starts with inflammation ( i.e. your immune system responding to a pathogen ) via T lymphocytes which recognise myelin derived antigens on the surface of the microglia ( nerve cells ) which then starts an inflammatory cascade resulting in the destruction of the myelin sheath, within the central nervous system ©
  8. 8. 8 23/09/2012CONSEQUENCES OF PATH This results in acute and chronic plaque formation within the CNS, oedema and auto immunity in the immune system Changes occur in the HPA axis which affects the thyroid and all metabolic function and sexual function in the body as well as musculo/skeletal function. ©
  9. 9. 9 23/09/2012 RESULTS OFPATHOLOGY PROCESS Removing the myelin sheath from neuronal fibres means that the signals can jump from fibre to fibre and thus get muddled up or not delivered. Signals (neurotransmitters) are molecules which depend on an electrochemical gradient – ions. If there are any nearby molecules which attract ions ( positive and negative charges) the normal signal transduction may not take place. I compare this to: ©
  10. 10. 10 23/09/2012 THE EFFECT Is like a plug which is not earthed Resulting in a blown fuse – replace the fuse but if the plug is not earthed another bulb will go! ©
  11. 11. 11 23/09/2012 MS SYMPTOMS – some Optic neuritis, facial palsy Relapsing and remitting sensory symptoms e.g. tingling in the hands 6th cranial nerve palsy (eye movements) Tingling on the spine ( Lhermitte’s syndrome ) Spasticity, pain, ataxia, fatigue, bladder and impotence issues Sub acute patterns of symptoms over time ©
  12. 12. 12 23/09/2012 Conventional approach Diagnosis: By exclusion Imaging & CSF examination Drugs: Interferon Beta ( not effective in early MS does not inhibit progression) Azathioprine Immunoglobulin Monoclonal antibody no proven overall efficacy delays progression increases likelihood of cvs events and hypothyroidism ( Oxford seminar) physiotherapy ©
  13. 13. 13 23/09/2012 SYMPTOM/ DRUGS Spasticity– baclofen Ataxia - clonazepam Pain - gabapentin Urinary – cathertization and anti cholinergics Fatigue – amitriptyline Impotence – viagra All the above have significant side effects with implications for MS ©
  14. 14. 14 23/09/2012 SURGERY Does not treat the causeVenous angioplasty in Multiple Sclerosis: neurological outcome at 2 yrs in acohort of relapsing – remitting patients. Salvi F. et al Funct Neurology 2012 Jan–Mar 27(1):55-9 Veins and arteries are often comprised entirely due to inappropriate diet ©
  15. 15. 15 23/09/2012 WHAT IS A MEDICAL HERBALIST A person who treats medical disease ‘wholistically’ on an evidence based basis with whole plant extracts A person who has trained in University, hospital, clinic environments A person who treats the cause of the problem not just the symptom We are specialists in the use of medicinal plants and their ability to resolve disease ©
  16. 16. 16 23/09/2012HOW AM I TRAINED? ©
  17. 17. 17 23/09/2012 PHILOSOPY MEDICAL HERBALISTS LOOK AT THE PATIENT AS A WHOLE NOT AS A SPECIFIC CONDITION OR PART OF A BODY MEDICAL HERBALISTS TREAT NOT JUST TO RESOLVE AN ISSUE BUT ALSO TO OPTIMISE HEALTH INCLUDING PREVENTION THE BODY IS LIKE A JIGSAW IF ONE PIECE IS MISSING THE REST IS OUT OF SYNC ©
  18. 18. 18 23/09/2012 HOW DO I TREAT?I review all aspects of the health of the person Diet, exercise Drugs, supplements Co-existing conditions – obesity, diabetes, pcos & other women’s issues, impotence, constipation etc. ©
  19. 19. 19 23/09/2012 HOW DO I TREAT? You may remember there was no mention of exercise or diet under the conventional approach This is the first step to review – especially as those with auto immunity are normally nutrient deficient Being nutrient deficient pre-disposes to immune disorder ©
  20. 20. 20 23/09/2012 Diet Linoleic acid levels are abnormally low in MS patients – diet should be rich in fatty acids COD LIVER OIL! FLAX SEEDS! ( helps constipation too !) Identification of naturally occurring fatty acids of the myelin sheath that resolve neuro-inflammation Ho PP et al Sci Transl Med 2012 June 6;4 (137) :137ra 73 ©
  21. 21. 21 23/09/2012 DIET Gluten intolerance may be a factor Hybridised grains and overconsumption Poor nutrition – lack of key vitamins, minerals in immunocompromised patients directly relates to poor function Inflammation mediated memory dysfunction and effects of a ketogenic diet Kim do et al Plos One 2012 7(5) 35476 High glucose levels affect the HPA ©
  22. 22. 22 23/09/2012 Vitamin D Deficiency Ontario is well known for its lack of vitamin D in the population – it is recognised to be endemic Reduced vitamin D is associated with the geographic incidence of MS Loss/Lack of vitamin D affects bones, muscles, thyroid, liver etc. ©
  23. 23. 23 23/09/2012 Is Lack of Vitamin D a co-factor? Yes, in making MS symptoms and long term health worse No, in direct causation Vitamin D deficiency is not associated with early stages of thyroid auto immunity Effraimidis G et al Eur J Endocr 2012 Apr 19 Vitamin D reduces remission Neurology. 2012;79:208-210, 254-260, 261- 266, 267-273 ©
  24. 24. 24 23/09/2012 Sugar Like all diseases of excess sugar plays a key role in destabilising the body’s normal mechanisms including brain function Excess sugar is derived from an inappropriate diet i.e. one high in grains Insulin resistance a hall mark of MS co morbidities e.g. PCOS High circulating levels of glucose affect the brain J.Physiol 2012 590:2485-2499 Gomez-Pinella ©
  25. 25. 25 23/09/2012 Exercise Exercise – improves brain function Makes tissues work better – import and export Improves cardiovascular function Erickson KI et al Exercise training increases the size of the hippocampus and improves memory. PNAS 31 Jan 2011epub ahead of print. ©
  26. 26. 26 23/09/2012 Review existing medications Statins - Inhibits the formation of cholesterol, but the myelin sheath is made from cholesterol, causes diabetes Impairs the immune system Bisphosphonates Cytotoxic to new red blood stem cells in bone marrow Proton pump inhibitors – inhibits the bodies’ immune system and first line of defence against pathogens ©
  27. 27. 27 23/09/2012 Review MS symptomsas expressed by the patientSuch as: Sleep issues Excretion issues Sexual issues Review these in conjunction with the thyroid and vitamin D consumption ©
  28. 28. 28 23/09/2012 Sub clinical hypothyroidism Iodine, selenium, zinc Directly impacts on the immune system, responsible for all metabolism in the body outside of the CNS Vitamin D Endemic in Ontario not available in our local soils ©
  29. 29. 29 23/09/2012 Review the Patient’s other symptoms Spasticity Movement Cognitive functionAnd so on and then select appropriate plants toalleviate, reduce symptoms ©
  30. 30. 30 23/09/2012 PlantsI choose the plants that offer the medical therapeutics that patients need in combination to maximise synergy of the biochemicals based on published scientific evidence InMS we have two outstanding plants Curcuma longa Scentella asiatica ©
  31. 31. 31 23/09/2012 Curcuma Longa & Scentella Asiatica Recent Pat CNS Drug Discov. 2012 Jun 21. Curcuminoids in Neurodegenerative Diseases. Kim DS, Kim JY, Han Y. Curcumin has bright prospects for the treatment of multiple sclerosis.Xie L, Li XK, Takahara S.Int Immunopharmacol. 2011 Mar;11(3):323-30. Neurol Sci. 2012 Aug 4. Centella asiatica attenuates the neurobehavioral, neurochemical and histological changes in transient focal middle cerebral artery occlusion rats.Tabassum R, et al.Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard (Hamdard University), New Delhi, 110062, India. Evid Based Complement Alternat Med. 2012;2012:946259. Epub 2012 May 14. Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential. Orhan IE. ©
  32. 32. 32 23/09/2012 Plants Withania – adaptogens Astragalas – anti inflammatories Nervines to modify dopamine vs. serotonin e.g. Passionflower and St John’s Wort Milk Thistle – hepatics Hypoglycaemics – Cinnamon ©
  33. 33. 33 23/09/2012
  34. 34. 34 23/09/2012 HOW THEY WORK Plantshave many chemicals in them which work at many levels of the bio-chemical pathways of the body in a synergistic fashion. Conventional drugs in order to be patented can only work in one way with one key chemical – it is this direct action which causes many of the side effects. ©
  35. 35. 35 23/09/2012 Medical marijuanaI am not a supporter of the use of this plant as the cannabinoids alter brain function over the long term Synthetic versions cannot be the same as in Cannabis sativa and may either not produce the result desired or worse Marijuana relieves spasticity but affects cognitive function Corey-Bloom J.et al. CMAJ May 14 2012 ©
  36. 36. 36 23/09/2012VIBURNUM OPULUS - BARK ©
  37. 37. 37 23/09/2012 ANTI SPASMOLYTICS Thereare a number of plants which provide anti spasmolytic actions which can be equally effective or more than marijuana without the associated cognitive problems Theseare normally given as part of the treatment protocol by a Medical Herbalist ©
  38. 38. 38 23/09/2012 SUPPLEMENTS There are some specific supplements beneficial in MS such as pure Cod Liver Oil Retail supplements are not allowed by law to have a medical effect and thus the doses suggested maybe inappropriate Always consult your professional practitioner first before purchasing ©
  39. 39. 39 23/09/2012 CAUTIONS PLEASE NOTE: IT IS ADVISED, THAT ANY PLANTS MENTIONED IN THIS TALK, ARE ONLY USED UNDER PROFESSIONAL GUIDANCE. BOTANICAL MEDICINE AS COMPOUNDED BY A PROFESSIONAL IS NOT AVAILABLE OVER THE RETAIL COUNTER. It is not advisable to self treat A professional: will recognise all the issues within the body ;Select herbs that will impact positively on these issues withoutcausing problems in order to co exist with orthodox drugs, ©
  40. 40. 40 23/09/2012 References www. Pubmed, Science directI have a full list of references for those who are interested – if you would like either to email me or put your name down tonight I will send them to you. It is several pages! ©
  41. 41. 41 23/09/2012 THANK YOU MORWENNA GIVENWWW.MEDICUSHERBIS.COM © 2012

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