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Mohamed labib salem_cv_11_27_2014

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Mohamed labib salem_cv_11_27_2014

  1. 1. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 November 2014 Mohamed Labib Salem, PhD CURRICULUM VITAE CURRENT POSITIONS 9/2014 – 12/2014 Visiting Professer Department of Microbiology and Immunology Medical University of South Carolina, Charleston, SC, USA (+1) 843-327 6156; e-mail: salemm@musc.edu 2006 - Present: Professor of Immunology (Tenure Affiliation) Faculty of Science, Tanta University, Egypt Tel: +20-040 334-4352 (work) +20-01274272624 (mobile) FAX: +20-040 335-0804 E-mail: CECR@unv.tanta.edu.eg mohamedlabibsalem@yahoo.com mohamed.labib@science.tanta.edu.eg 8/2014 - Present Director, Delta Regional Development Research Center (DRDRC) Academy of Scientific Research and Technology, Tanta, Egypt 6/2013 – Present Director, Grants, Innovation & Technology Transfer Center (GITTC) Tanta University, Egypt Contact: CECR@unv.tanta.edu.eg 6/2013 – Present Director, Center of Excellence in Cancer Research (CECR) Tanta University, Egypt Contact: GITTC@unv.tanta.edu.eg PRIOR POSITIONS 2001-2010 Assistant Professer Surgery Department and Hollings Cancer Center Medical University of South Carolina, Charleston, SC, USA (+1) 843-792-7576 6/2010 – 6/2013 Director, Competitive Project Unit (CPU) Tanta University, Egypt Contact: GITTC@unv.tanta.edu.eg
  2. 2. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 Short Biography Mohamed L. Salem (PhD, 1995) is the Professor of Immunology at Tanta University, Egypt and Visiting Professor at Hollings Cancer Center and Department of Microbiology and Immunology, Medical University of South Carolina, USA. Dr. Salem is the Director of Delta Development Research Center which is a regional branch of Academy of Scientific Research and Technology, Egypt; Director of the Grant, Innovation & Technology Transfer Center, and Director of Center of Excellence in Cancer research, Tanta University, Egypt. Dr. Salem obtained his PhD in 1995 through a channel system between Tanta University, Egypt and Kyushu University, Japan. From 1997 -2001, he was a Postdoctoral Fellow at Kyushu University, Japan and from 2002-2010 as an Assistant Professor at Medical University of South Carolina, USA. Dr. Salem is member of the National Committee for Professorship Promotion (Zoology) and Member of the National Committee for the Biological Sciences. He is also a founder member of the Egyptian Society for cancer Research and Middle Eastern Association for Cancer Research, Canada. Dr Salem won the State Incentive Award in 2003 and the State Excellent Award in 2009 in Basic Sciences from the Academy of Scientific Research and Technology, Egypt based on his research on cancer immunotherapy. His h-index is 24 and published about 111 articles in peer-reviewed journals and attended more than 70 national and international workshops and conferences in Immunology. He supervised more than 50 Master and PhD students in cancer-related works. He is a member of several editorial boards of peer-reviewed journals as well as ad hoc reviewer for more than 80 journals. He has been invited to give talks in cancer immunotherapy in Egypt, UAE, Jordan, Saudi Arabia, USA, Canada, and Canada. Dr Salem’s research focuses on understanding the cellular and molecular mechanisms underlying how cancer and HCV escape from host immunity, in particular the rules of immunoregulatory cells including lymphoid and myeloid lineages. Additionally his research has been focusing on developing effective anticancer immunotherapies strategies, in particular the use of adoptive cell therapy. His research projects have been funded by National Institute of Health, USA, Science and Technology Development Fund (STDF), Egypt, National Academy of Sciences, USA and Tanta University, Egypt, as well as by industry.
  3. 3. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 EDUCATION 9/1991 - 12/1995 PhD (ImmunoEndocrinology) The thesis was accomplished in the Department of Immunology, Kyushu University, Japan (27 months) from October 1992 to December 31, 1995). The research project was funded by a pre- doctoral fellowship from the Cultural Affairs and Missions Sector, Ministry of Higher Education, Egypt. PhD Graduation was from Tanta University, Egypt (Total period: 9/1991 ~ 12/1995). 04/1999 - 3/2001 PhD Courses in Pathological Sciences Completed 2 years out of 3 years required for Ph.D. in Pathological Sciences, Department of Immunology, Medical Institute of Bioregulation, Kyushu University, Japan () through a scholarship from Ministry of Higher Education (Monbukagakusho), Japan. 9/1985 – 9/1989 MSc (Comparative Anatomy) Faculty of Science, Tanta University, Egypt 10/1979 – 6/1984 BSc (General Zoology) Faculty of Science, Tanta University, Egypt ACADEMIC POSITIONS 2006 - present Professor: Immunology Zoology Department, Faculty of Science, Tanta University, Egypt 2002 – 2010 Assistant Professor: Department of Surgery and Hollings Cancer Center, Medical University of South Carolina, USA 2001 – 2002 Postdoctoral Fellow Surgery Department and Hollings Cancer Center, Medical University of South Carolina, USA 2002- 2006 Associate Professor Zoology Department, Faculty of Science, Tanta University, Egypt 1997 - 2001 Research Fellow Department of Immunology Kyushu University, Japan 1995-1996 Assistant Lecturer: Faculty of Science, Tanta University, Egypt 1992-1994 PhD Researcher Department of Immunology, Medical Institute of Bioregulation, Kyushu University, Japan 1989-1992 Assistant Lecturer Faculty of Science, Tanta University, Egypt 1984-1989 Demonstrator Faculty of Science, Tanta University, Egypt
  4. 4. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 OVERALL RESEARCH PERFORMANCE h-index: 22 SCOPUS 24 Google Scholar Citation: 1656, SCOPUS 2396, Google Scholar PRIZES, HONORS and AWARDS A- Prizes  State's Excellence Award in Basic Sciences (2009/2010): Academy of Scientific Research and Technology, Egypt.  State's Incentive Award in Biology (2003/2004): Academy of Scientific Research and Technology, Egypt. B- Awards  Senior Research Fellowship Award to visit Medical University of South Carolina, USA for 6 months, Ministry of Higher Education, Egypt (July 2012).  The Educational Institute on Responsible Research on Infectious Diseases: Ensuring Safe Science in the 21th Century sponsored and organized b U.S. National Academy of Sciences, Aqaba, Jordan, 8-13 September, 2012.  2011 CAS-TWAS Visiting Scholar Award: Third World Academy of Science (TWAS), 2010. Three- month award to visit Chinese Academy of Science, Beijing, China  Selective Poem award: "Title: We All Shall Die", International Society of Poets, 2006.  Selective Poem award: "Painless Pain", International Society of Poets, 2006.  Research Excellence Award: Marine Polymer Technologies, Inc., 2006  Research Fellow Scholarship, Ministry of Higher Education, Japan (October 1997-March, 2001) C- Recognition  Faculty of Science Distinguished Award, Tanta University, Egypt, September 2014.  Distinguished Award, Association for American-Egyptian Scholars in North America during the Annual Meeting of the association, December 2012, Ain Shams University, Cairo, Egypt.  Certificate of Merit from Society of Friends of Zweial City for giving several talks and workshops to K12, under- and postgraduate students and researchers, Egypt, February 2014).  Syndicate Shield: Behira Scientific Syndicate Shield as recognition for giving several talks to young practioners and researchers, Damanhur, Egypt, February 2013.  Tanta University (Egypt) Shield: for the scientific achievement, November, 2010.  Gharbia Governorate (Egypt) Shield: for the scientific achievement, November, 2010.  The Conference Shield: the 6th International Conference on Biological Sciences, Faculty of Science, Tanta University, Egypt, November 2010.  Tanta University (Egypt) Shield: for the scientific achievement, November, 2004.  Gharbia Governorate (Egypt) Shield: for the scientific achievement, November, 2004.  Certificate of Merit: the First Conference of Applied Prophetic Medicine organized by Abha
  5. 5. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 Private Hospital, Saudi Arabia, 19 to 21 February 2008.  Certificate of Merit: National Science Club Committee, The first meeting of the Science Clubs competition for the Universities in Egypt held at Cairo University 21/11/1996. TEACHING EXPERIENCE A- Medical University of South Carolina, USA Tumor Immunology: Postgraduate Students, Development of Molecular Cancer Therapies (Course ID: MBIM 716); Basic Immunology (Course ID: MBIM 775*01) (2005-2010) B- Damanhur University, Egypt Immunology: Postgraduate students, Zoology Department, Faculty of Science (2012/2013). Molecular mechanisms of Diseases: Postgraduate students, Zoology Department, Faculty of Science (2013/2014). Stem Cell Biology: Postgraduate students, Zoology Department, Faculty of Science (2013/2014), (2012/2013). Cancer Genetics: Postgraduate students, Zoology Department, Faculty of Science (2013/2014). C- Kafr Elsheikh University, Egypt Immunology and Hormones: Postgraduate students, Zoology Department, Faculty of Science (2012/2013). D- Damietta University, Egypt Immunology and Enzymes: Postgraduate students, Zoology Department, Faculty of Science (2012/2013). E- Tanta University, Egypt Undergraduate courses Immunology: Level 2 and Level 4, Undergraduate Students, Zoology Students, Zoology Department, Faculty of Science (2013/2014). Immunology: Level 4, Undergraduate Biochemistry students, Chemistry Department, Faculty of Science (2010/2011) Animal Biotechnology: Level 2 and Level 4, Undergraduate Biology Students, Biochemistry and Biophysics Department, Faculty of Science (2013/2014). Cell Biology and Genetics: Level 2, Undergraduate Biology, Biochemistry Students, Biophysics Students Biochemistry Department, Faculty of Science (2012/2013), (2011/2012), (2010/2011), (1996/1997). Cancer Biology: Undergraduate Biochemistry students (4th grade), Chemistry Department, Faculty of Science (2010/2011) Postgraduate courses Immunology: Postgraduate Students, Zoology Department, Biochemistry Department, Faculty of Science (2013/2014), (2012/2013). Experimental Biology (Immunology): Postgraduate students, Zoology Department, Faculty of Science (2011/2012), (2010/2011), (1996/1997).
  6. 6. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 RESEARCH INTEREST My research interest focuses on the following three main directions.  Understanding the cellular and molecular mechanisms governing the dysfunction of anti- cancer and anti-tumor immune responses:  Developing effective anti-tumor immunotherapeutic regimen  Stem cell-based therapy in cancer and inflammatory diseases.  Modulation of immune cells using from natural products: RESEARCH SUPPORT (22 grants total) Active Grants 1. Establishing Grants, Innovation & Technology Transfer Center (GITTC) at Tanta University. Source: Academy of Scientific Research and Technology, Egypt Period: 1/07/2014- 31/06/2016 Fund: 700,000 L.E. (about $100,000) Role: Principal Investigator 2. Establishing Delta Thalassemia Center: Control and Prevention (DTCP) Source: Science and Technology Development Fund (STDF), Egypt Period: 1/12/2014- 30/11/2016 Fund: 5,000,000 L.E. (about $650,000) Role: Co-Principal Investigator 3. Establishment of Delta Regional Technological Center for Textiles : phase one Source: Academy of Scientific Research and Technology, Egypt Period: 1/07/2014- 31/06/2016 Fund: 1000,000 L.E. (about $130,000) Role: Project Director 4. Genetic Center for fostering next generation translational cancer research Source: Ministry of Higher Education, Egypt Period: 1/02/2014- 31/01/2016 Fund: 4,000,000 L.E. (about $600,000) Role: Co-Principal Investigator 5. Establishing Center of Excellence of Cancer Research (CECR) at Tanta University (Project ID#: 5245) Source: Science and Technology Development Fund (STDF), Egypt Period: 1/04/2013- 31/03/2015 Fund: 9,650,000 L.E. (about $1.800,000) Role: Principal Investigator 6. The use of artesunate-loaded nanoparticles tagged with transferrin as a novel targeting therapy of experimental colon cancer (Project ID#: 4982 Source: Science and Technology Development Fund (STDF), Egypt Period: 1/12/2013- 30/11/2015
  7. 7. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 Fund: 850 ,000 L.E. (about $120,000) Role: Co-Principal Investigator 7. Dysfunctional myeloid cells as a predictor of failure of chronic HCV patients to interferon therapy (Project ID# 1469) Source: Science and Technology Development Fund (STDF), Egypt Period: 31/08/2010- 30/10/2013. Fund: 1,736,160 L.E. (about $300,000) Role: Principal Investigator Intramural grants Funded by Tanta University, Egypt (100,000 L.E. each over 2 years) 8. Biotechnology based vaccination with mRNA for cancer immunotherapy. Role: PI 9. Loading nanoparticle into stem cell as a novel technology for the delivery of anticancer drugs. PI: Dr. Nageh Mahdy, Faculty of Medicine, Tanta University. Role: Co-PI. 10. The use of stem cells from Egyptian patients with chronic HCV to generate functional dendritic cells for immunotherapy. Role: PI 11. Stem cell therapy as novel therapeutic intervention in resistant cases of alopecia. PI: Dr. Iman Al-Maadawy, Department of Dermatology, Faculty of Medicine, Tanta University. Role: Co-PI 12. Utility of autologous bone marrow stem cells for treatment of chronic leg ulcer. PI: Prof. Said Hamad (Clinical Pathology Dept, Faculty of Medicine, Tanta University, Egypt). Role: Co-PI 13. Enhancing the antitumor efficacy of heterocyclic materials by loading into polymer. PI: Prof. Ahmed EL-Barbary (Chemistry Dept, Faculty of Science, Tanta University, Egypt). Role: Co-PI 14. Role of mosquitoes in Transmission of Hepatitis C virus. Samar Ezzat Ghazy El-Kholy. PI: Dr. Samar Ghazy (Zoology Department, Faculty of Science, Tanta University, Egypt). Role: Co-PI 15. Synthesis of chalcones and their metal complexes as novel anticancer materials. PI: Prof. Gaber Abou Al-Azm (Chemistry Department, Faculty of Science, Tanta University, Egypt). Role: Co-PI 16. Analysis of interferon receptors expression, mutation, and polymorphism in chronic HCV patients. Prof. Abdel Raouf Abou Alazm (Department of Tropical Medicine, Faculty of Medicine , Tanta University, Egypt). Role: Co-PI Completed Grants 17. Maximizing memory T cell responses by matured post chemotherapy dendritic cells Source: R01/National Cancer Institute (Grant #: RCA133503A) Period: 4/1/2010- 3/31/2014 Fund: $250,000/year (3 years) Role: Principle Investigator from March 2010-October-2010. Curent role: Consultant. 18. Altering post vaccination T cell contraction Source: R01/National Cancer Institute (Grant #: R01 CA083672-04a1) Period: 1/4/2004-04/30/2009 Fund: $250,000/year (5 years) Role: Co-Investigator; Principle Investigator, David J Cole
  8. 8. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 19. Preclinical assessment of the novel peptide-based cancer vaccine F2 gel/CEA/IL-12 Source: Department of Defense (DOD) (Grant#: GC-3609-04-43766CM) Period: 11/01/2004-10/31/2006 Fund: $80,000/year (2 years) Role: Principle Investigator 20. Immature myeloid immunosuppressor cells in breast cancer patients: Implications for anti- tumor vaccination Source: Hollings Cancer Center, Medical University of South Carolina Period: 01/01/2005-12/13/2007 Fund: $55,000/year (1 year) Role: Principle Investigator 21. Circulating myeloid suppressor cells in breast cancer patients: Implications for future vaccine development Source: Chain Reaction for a Cure a Breast Cancer Period: 01/01/05-21/31/2006 Fund: $15,000 (1 year) Role: Principle Investigator 22. Evaluation of F2 gel/IL-12-based vaccination on hepatic fibrosis and protection after Schistosoma mansoni infection Source: Marine Polymer Technologies Inc., Danvers, Massachusetts Period: 06/01/2004-3/30/2007 Fund: 180,000 L.E. (30 months) Role: Principle Investigator 23. In Vivo Effector T Cell Response to Peptide Vaccination Source: National Cancer Institute (R01) Period: 07/01/01-06/30/2004 Fund: $250,000 (3 years) Role: Co-Investigator; Principle Investigator, Dr. David J Cole, MD 24. Characterization of p-GlcNAc as an immune adjuvant and a delivery system for cytokines Source: Marine Polymer Technology, Boston, USA Period: 07/01/01-06/30/2004 Fund: $32,000 (30 months) Role: Co-Investigator; Principle Investigator, Dr. William Gillanders, M.D. 25. New Technology for control of the intermediate host of schistosomiasis in Egypt, Laboratory and semi field application Source: Tanta University, Egypt Period: 01/01/97-12/31/2003) Fund: 100,000 L.E./year (3 years) Role: Co-Investigator; Principle Investigator, Dr. Mohamed Mona, PhD
  9. 9. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 PATENTS/DISCLOSURE I am a part of a joint invention disclosure with the University of California (San Diego, California, USA) and Medical University of South Carolina (Charleston, SC, USA) on methods to optimize the biological activity of recombinant growth factors that mobilize hematopoietic stem cells from bone marrow in cancer patients after chemotherapy (http://gtp.autm.net/technology/view/47058). NATIONAL/INTERNATIONAL COMMITTEES 1- Member and Secretary, The University Steering Committee for over viewing the funded projects at Tanta University funded by National and International sources. June 2013-now. 2- Member, Strategic Research Committee, Tanta University, Egypt. June 2014-now. 3- Ethical Research Committee, Faculty of Medicine, Tanta University. November 2014-now. 4- Coordinator, Faculty of Science Ethical Committee, Faculty of Science, Tanta University, Egypt, December 2012. 5- Member, Center of Environmental Outreach and Sustainable Development, Tanta University, December 2012. 6- Member, College Board, Faculty of Science, Tanta University, October 2012-September 2013. 7- Member, Institutional Animal Care Ethical Committee, Zoology Department, Faculty of Science, Cairo University, Egypt 8- Member, Egyptian Universities Promotion Committee (EUPC): Zoology and Entomology Committee, 2012-2015 cycle. 9- Member, Tanta University Committee for Award and Prize, Tanta University, Egypt. 10- Member of the Board of Directors, Community Service and Environment Development, Faculty of Medicine, Tanta University, Egypt, 2010/2012. 11- Member, Community Service and Environment Development, Faculty of Science, Tanta University, Egypt; 2010/2012 12- Executive member, Board of Director, Condolence Society of Hematological Diseases for Patients and Family, Egypt. 13- Executive member, Middle-Eastern Association for Cancer Research (MEACR), Canada 14- Member, Postgraduate Committee for Postgraduate Courses, Faculty of Science, Tanta University, Egypt; 2010/2012. 15- Member, Postgraduate Research Committee of Zoology Department, Faculty of Science, Tanta University, Egypt; 2010/2012. 16- Advisory Committee For Flow Cytometry Facility: Hollings Cancer Center, Medical 17- University of South Carolina, Charleston, SC, USA (2007 - Present) 18- Coordinator, How to write a TEMPUS project: A workshop organized by Competitive Project Unity, Tanta University on December 10, 2012, Faculty of Medicine, Tanta University, Egypt. 19- Coordinator, Writing a Scientific Proposal for PostDoc, A workshop organized by Competitive Project Unity in collaboration with DAAD, Cairo on December 16, 2012, at Development Project Unity, Tanta University, Egypt. 20- Coordinator, How to write a competitive project: A workshop organized by Competitive Project Unity, Tanta University on September 12, 2012, Faculty of Agriculture, Tanta University, Egypt.
  10. 10. Curriculum Vitae Mohamed Labib Salem, PhD November 2014 EDITORIAL BOARD REVIEW DUTIES American Journal of Biomedical Research Journal of Genetic Engineering and Biotechnology American Journal of Immunology (Science Publication); Regional Editor Annals of Clinical and Laboratory Research (Editor-in-Chief / Journal Manager) Bioscience Cancer Research Journal Egyptian J Parasitology Egyptian Journal of Experimental Zoology, Egypt Hematology Research and Reviews; Dove Medical Press; Honorary Editor ISRN Immunology Journal of Basic and Applied Zoology, Chief-Editor of Immunology. Journal of Vaccine and Vaccination Journal of Vaccine and Vaccination The Clinical Cancer investigation Journal The Open Cancer Immunology Journal The Scientific World JOURNAL (Immunology and Inflammation) JOURNAL REVIEWS (82 Journals) American Journal of Microbiological Research; Animal Biology; African Journal of Biotechnology; Agriculture Research; Archives of Medical Research; Arthritis and Rheumatism; BioDrugs; Biologics: Targets & Therapy; Cancer Immunology and Immunotherapy; Cancer Research; Cancer: Targets and Therapy; Cellular Immunology; Cellular and Molecular Immunology, CURRENT CANCER DRUG TARGETS ; Current Drug Target; Cytokine; Cytotechnology; Egyptian Journal of Parasitology; Endocrine Metabolic Immune Disorders- Drug Targets; European Journal of Gastroenterology & Hepatology; Evidence Based Complementary & Alternative Medicine; Experimental Lung Research; Experimental Parasitology; Expert Review of Vaccines; Finding in Exp. and Clinical Pharmacology; Fundamental & Clinical Pharmacology; Future Drugs Ltd; Future Medicine, Hematology Research and Reviews; Human and Experimental Toxicology; Human Immunology; Ibnosina Journal of Medicine and Biomedical Sciences; Immunology and Cell Biology ; Immunology Letter ; International J Medicine & Medical Sciences ; International J Pharmacy & Pharmacology; International Immunopharmacology; ISRN Immunology; J Advanced Research; J Basic and Applied Zoology; J Biological Sciences ; J Biomaterials Science: Polymer Edition; J Clinical Immunology and Immunopathology Research; J Cellular and Molecular Medicine; J Environmental Chemistry and Ecotoxicology ; J Genetic Engineering and Biotechnology; J Immunology and Cell Biology; Journal of Infectious Diseases and Therapy; J Infection in Developing Countries ; J Interferon and Cytokine Research ; J Medical Laboratory and Diagnosis; J Medicine and Medical Sciences; J Neuroimmunology; J Parasitology Research; J Pharmacy and Pharmacology ; J Pharmacy and Bioallied Sciences; J Zhejiang University-SCIENCE B; Libertas Academica; Medical Principles and Practice ‘ Medical Science Monitor; Methods and Findings in Experimental & Clinical Pharmacology ; OncoTargets and Therapy ; Oral Diseases; Pharmaceutical Biology; Planta Medica ; Recent Patents on Inflammation & Allergy Drug Discovery ; Saudi Medical Journal ; The Egyptian J of Experimental Biology; The Egyptian J of medical Sciences; The Open Vaccine Journal ; Toxicology; Turkish Journal of Veterinary & Animal Sciences ; Vaccine ; Universal Journal of
  11. 11. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 11 Medicine Dentistry ARBITRATION COMMITTEES  Scientific Committee to promote professors of Immunology, Beirut University, Lebanon  Scientific Committee to promote professors of Zoology, Insects and Oceanography, Al-Azhar University, Egypt  Egyptian Universities Promotion Committee (EUPC) to promote professors of Zoology  National Organization for Drug Control and Research  Higher Professorship Promotion Committee, AL-Basra University, Iraq  Higher Professorship Promotion Committee, AL-Kindy University, Baghdad, Iraq  Higher Professorship Promotion Committee, Taez University, Yemen Republic ARBITRATION COMMITTEES Master theses (MSc; 36 theses) 1. Hosam Askar (BSc): Investigation of the effects of medicinal plants on the immune system in normal and tumor bearing mice during chemotherapy. Zoology Department, Faculty of Science, Al-Azhar University (Assuit Branch), Egypt. Registered in 12/2014. Role: Co- Supervisor. 2. Asmaa Algamal (BSc): Immunomodulatory and antitumor effects of chalcones and metal complexes in a tumor mouse model. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in April 2014. Role: Co-Supervisor. 3. Iman Hamada (BSc): Effects of bone marrow products on leucopenia induced by chemotherapy in tumor-bearing mice. Zoology Department, Faculty of Science, Dumiata University, Egypt. Registered in January 2014. Role: Co-Supervisor. 4. Ibrahim Eissa (BSc): Evaluation of therapeutic effectiveness of dendritic cells based vaccination in a preclinical cancer model. Chemistry Department, Biochemistry Division, Faculty of Science, Tanta University, Egypt. Registered in January 2014. Role: Co-Supervisor. 5. Nesma Mohamad Samy Mohamad Gamal El-Dein Zaghow (BSc): (Effect of autologous bone marrow mononuclear cell transplantation on a preclinical myocardial infarction model in rat. Dept. of Pharmacology & Toxicology, Faculty of Pharmacy, Tanta University, Egypt. Registered in January 2014. Role: Co-Supervisor. 6. Shymaa Kamal (BSc): A comparative preclinical study oncholesterol-lowering and immunomodulatory effects of probiotics bacteria and algae. Sadat Institute of Biotechnology, Menofia University, Egypt. Registered in February 2014. Role: Co- Supervisor. 7. Asmaa Abo Bakr Elshohat (MD): Investigating the potential Immunomodulatory Effects of Spirulina on Thalassemic children. Pediatric Department, Faculty of Medicine, Tanta University, Egypt. Registered in January 2014. Role: Co-Supervisor. 8. Sherin Hamed Mostafa Abo el-ola (BSc): Effect of human umbilical cord mononuclear cells on hepatic fibrosis. Department of Pharmacology & Toxicology. Faculty of Pharmacy, Tanta University, Egypt. Registered in November 2013. Role: Co-Supervisor. 9. Mona Zidane (MSc): Modulatory effects of synthetic double-stranded RNA on immune and tumor cells from leukemic patients. Experimental Zoology Division, Zoology Department,
  12. 12. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 12 Faculty of Science, Tanta University, Egypt. Registered in November 2014. Role: Main Supervisor. 10. Shymaa Sobhy (MSc): Analysis of circulating cancer and regulatory immune cells in patient with myeloid leukemia. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in November 2013. Role: Main Supervisor. 11. Dina Ghoraba (BSc): Effect of human umbilical cord mononuclear cells on breast cancer in mice. Pharmacology & Toxicology Department, Faculty of Pharmacy, Tanta University. January 2014. 12. Dina Ismail (BSc): Immunological and Molecular Pathology Studies on Murine Stomach Carcinogenesis in Relation to Inflammation. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in November 2013. Role: Main Supervisor. 13. Eman Maher El-Bayoomy (BSc): Assessment of the relationship between psychological locus of control and immune status in cancer patients. Faculty of Science, Cairo University, Egypt. Registered in April 2013. Role: Co- Supervisor. 14. Nadia Abdel Aziz Abelmonem ELnakeeb (BSc):Assessment of some biochemical and immunological signature on chronic HCV patients in Egypt. Faculty of Science, Port-Said University, Egypt. Registered in April 2013. Role: Co- Supervisor. 15. Mohamed Ibrahim Fatoh (BSc): Phenotypic characterization of dendritic cells in the blood of children with idiopathic immune thrombocytopenic purpura. Immunology Division, Zoology Department, Faculty of Science, Cairo University. Registered in January 2013. Role: Co- Supervisor. 16. Ashraf Ibrahim ALsabbagh MBBCH, D.T.M (MSc study): Detection of Myeloid-derived Suppressor Cells in Peripheral Blood and Ascetic Fluid in Patients with Hepatocellular Carcinoma. Department of Tropical Medicine, Faculty of Medicine, Tanta University, Egypt. Registered in January 2013. Role: Co-Supervisor. 17. Maii Moustafa Kamel Nabeih (BSc): Antiviral responses of Lactobacillus in chronic hepatitis C virus patients. Microbiology Division, Botany Department, Faculty of Science, Tanta University, Egypt. Registered in December 2012. Role: Co-Supervisor. 18. Samar Alkasaas (BSc) Chemistry Department, Faculty of Science, Tanta University, Egypt. Registered in April 2012. Role: Co-supervisor. 19. Asmaa Abd Elsamad Altaramsy (BSc): Immunological and Biochemical characteristics of activated immune cells. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in November 2012. Role: Main Supervisor. 20. Doaa Ahmed Samy (BSc): Analysis of miRNA expression in immune and cancer cells during tumor progression and anti-cancer therapy. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in October 2012. Role: Co-Supervisor. 21. Rania Ibrahim (MSc study): Investigation of the Role of Stem cells in Cancer Immunotherapy in a Mouse Model. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in April 2012. Role: Main supervisor. 22. Asmaa Shaaban Youssif Atta (BSc): Optimizing T-cell reactivity in vitro to enhance anti-tumor immunotherapy in vivo. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in November 2012. Role: Main Supervisor. (GRADUATED) 23. Asmaa Ahmed Salama (BSc): Assessment of the impact of aging of T cells on the anti-tumor immunotherapy in an adoptive transfer mouse model. Zoology Department, Faculty of Science,
  13. 13. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 13 Tanta University, Egypt. Registered in January 2012. Role: Co-Supervisor. (GRADUATED) 24. Lamia Mostafa Elsayed AboElkher (BSC): The use of nanotechnology to improve the immunostimulatory effects of the synthetic double-stranded RNA polyriboinosinlic cytidylic acid. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered in April 2012. Role: Main supervisor. 25. Sohaila Mohamed Galal (BSc): Assessment of the impact of acute inflammatory signals on the anti-tumor immunity in a mouse tumor model. Zoology Department, Faculty of Science, Tanta University, Egypt. Registered August 2011. GRADUATED. Role: Co-supervisor. 26. Rana Medhat Ahmed Aly Zend (BSc): Protective effect of Spirulina platensis on cyclophosphamide-induced toxicity in experimental animal. Botany Department, Faculty of Science, Tanta University, Egypt. Registered March 2011. Role: Co- supervisor. 27. Shaima Talat (BSc): Investigation of the anti-cancer and immunmodulatory effects of novel derivatives synthesized from conventional chemotherapeutic drugs. Zoology Department, Faculty of Science, Tanta University, Egypt. March 2011. GRADUATED. Role: Main supervisor. 28. Wafaa Khalaf (MSc study): Immunomodulatory and anti-tumor effects of the Egyptian Scorpion venom Androctonus amoreuxi using murine models. Zoology Department, Faculty of Science, Suez Canal University, Egypt. Registered in 10, 2011. Role: Co-supervisor. 29. Heba Ahmed Mossad Taha (BSc): Investigation of the Potential Anti-fibrotic Activity of some conventional drugs using a model of Experimental Liver Fibrosis. Zoology Department, Faculty of Science, Damietta Branch, Mansoura University, Egypt. Registered March 2011. Role: Co- supervisor. 30. Wafaa Abdelhady Mohamed Taha (BSc): Screening of the immunmodulatory and antitumor activities of some algae in the Egyptian fauna. Sadat City for Scientific Research and Technology, Menofeya University. Registered November 201 0. Role: Co-supervisor. 31. Amro Elsherbeny Mohamed Elsherbeny (BSc): Evaluation adjuvant efficacy and ameliorating the side effects of some medicinal plants on cyclophosphamide treatment using Ehrlich ascites carcinoma model. Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University. Registered January 2011. Role: Co-supervisor. 32. Samah Kotb El-sayed Nasr El-deen (BSc): Evaluation of the role of some Toll- like receptor ligands as adjuvant for Schistosoma mansoni vaccination. Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University. Registered January 2011 and graduated September 2012. Role: Co-supervisor. (GRADUATED) 33. Afnan Hamdy Sobhy ELgowily (BSc): Immunological and Biochemical impact of praziquantel and cisplatin on experimental Schistosoma mansoni infection and Ehrlich ascite carcinoma. Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University. Registered January 2011. Role: Co-supervisor. 34. Iman M. Yoness (BSc): Interference of anti-inflammatory drugs with azoxymethane- induced colon cancer . Zoology Department, Faculty of Science, Tanta University Completed 2001. Role: Co- supervisor. (GRADUATED) 35. Heba M. Al Ashry (BSc) : Interference of inflammatory and anti-inflammatory drugs with Trichnella spiralis infection . Zoology Department, Faculty of Science, Tanta University. Completed 2003. Role: Co-supervisor. (GRADUATED) 36. Asmaa L. Mohamed Adawy (BSc): Interference of histamine and its antagonists with mammary adenocarcinoma. Zoology Department, Faculty of Science, Tanta University. Completed 2009.
  14. 14. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 14 Role: Co- supervisor. (GRADUATED) Doctorate Theses (PhD); 15 theses) 1. Sohaila Galal (MSC): Analysis of metabolic and immunological signatures in hematological malignancy using genomic and bioinformatic technologies. Zoology Department, Faculty of Science, Tanta University, Egypt. Role: Co- Supervisor. Registered in December 2014 2. Shimaa Abo Al Soud Taha (MSc): Effect of low dose Naltrexone with or without 5-Fluorouracil on Ehrlich tumor in mice. Pharmacology Department, Faculty of Medicine, Tanta University. Role: Co-Supervisor. 3. Engy Elsayed Ibrahim Ghonem (MSc): Immunoregulatory and anticancer effect of bioactive materials extracted from some mollusca inhabiting Egyptian marine water. Zoology Department, Faculty of Science, Tanta University. Role: Co-Supervisor. February 2014. 4. Haitham M (MSc): Comparative histological and immunological studies on young and aged inbred and outbred mice. Zoology Department, Faculty of Science, Zagazig University, Egypt . Role: Co- Supervisor. Registered in December 2013 5. Yara Abd-Elsalam Mohamed Helal (MSc): Evaluation of the Anti-Tumor Effect of the Niacin through the PARP. Registered in December 2012 Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Egypt . Role: Co- Supervisor. 6. Muhammad El-Shafeey Ahmed El-Shafeey (MSc): The use of hematopoietic stem cells in the treatment of liver inflammations. Medical Biotechnology Department, GEBRI- CSRTA. Registered in December 2012 at Experimental Zoology Division, Zoology Department, Faculty of Science, Tanta University, Egypt . Role: Main Supervisor. 7. Edris Mohamed (MSc): Enhancing stem cell mobilization during cancer chemotherapy using natural products with anti-oxidant and immune-stimulant activities. Experimental Zoology Division, Zoology Department, Faculty of Science, Faculty of Science, Tanta University, Egypt. Registered in October 2012 . Role: Main Supervisor. 8. Enas Abdel Raouf Mohamed (MSc): The role of stem cell based therapy in correction of immune dysfunction. Physiology Division, Zoology Department, Faculty of Science Faculty of Science, Tanta University, Egypt. Registered in September 2012 Role: Main Supervisor. 9. Khalid Mohammed Mahmoud ElAzab (MSc): Investigation of the biological changes in some Egyptian women with ovarian cancer. Physiology Division, Zoology Department, Faculty of Science, Mansoura University, Egypt. Registered in July 2012 Role: Co- Supervisor. 10. Ghada Mohammad Zaki Al-Ashmawy (MSc): Effects of immunomodulating drugs on in vitro generation and differentiation of dendritic cells from human peripheral blood mononuclear cells. Department of Biochemistry, Faculty of Pharmacy, Tanta University, Egypt. Registered in July 2012 Role: Co- supervisor. 11. Asmaa Abed El-hay Metwally Adawy (MSc): Optimization of the Immunomodulatory and Anti- Tumor Effects of Thymoquinone Using Nanotechnology in a Mouse Model. Zoology Registered in April 2012. Role: Main supervisor. 12. Shahinaz M. Shams (MSc): Enhancing pharmacokinetic and in vivo antitumor activity of 5- fluorouracil By tumor targeting polymeric nanoparticles. Pharmacology Department, Faculty of Medicine, Tanta University. Registered in April 2011. Role: Co- supervisor. 13. Abdel Aziz Awad Zidan (MSc): Zoology Department, Faculty of Science, Tanta University and University of Florida, USA (PhD, 2010~). Generation of T cells with stem-like phenotype using IL-
  15. 15. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 15 12 for anti-tumor adoptive immunotherapy . Started January 2011. Role: Main supervisor. (GRADUATED) 14. Hala Ahmed Mohamed Abd El-Hady (MSc): Zoology Department, Faculty of Science, Tanta University. Immunological evaluation of dendritic cells generated from patients with chronic hepatitis C virus and patients with hepatocellular carcinoma. Started January 2011. Role: Main supervisor. 15. Abeer Abdel Hamid Ahamed (MSc): Chemistry Department (Biochemistry Division): Biochemistry Division, Chemistry Department, Department, Faculty of Science, Tanta University. Biochemical Effects of Some Medicinal Plants in an experimental tumor model . Started January 2011. Role: Co- supervisor (GRADUATED). 16. Nahla A. AL Said (MSc): Zoology Department, Faculty of Science, Tanta University. Interference of anti-inflammatory drugs with Schistosomiasis infection. Completed 2001. Role: Co- supervisor. (GRADUATED) GRANT REVIEWS DUTIES 1- Project Management Unit, Ministry of Higher Education, Cairo, Egypt ( since 2014) 2- Mohamed Farid Khamis’s Foundation, Cairo, Egypt ( since 2014) 3- Research Fund Office, Cairo University, Egypt (since 2014) 4- Ad Hoc Science & Technology development Fund (STDF); Cairo, Egypt (since 2013) 5- Ad Hoc Scientific Reviewer: Misr Elkher (MEK); Cairo, Egypt. (since July 2013) 6- Academy of Scientific Research and Technology (ASRT); Cairo, Egypt (since 2010) 7- King Abdel Aziz City for Science and Technology (KACST), King Saudi Arabia (since 2011) 8- Deanship of Scientific Research, King Saud University, King Saudi Arabia (since 2011) 9- 2009 Breast Cancer Research Program - Idea and Postdoctoral-Endocrinology/Immunology (CDMRP BCRP IPD-END/IMM Panel), Department of Defense, Washington DC (Since 2010) 10- Special Emphasis Panel, National Institute of Health, Washington DC. (since 2009) 11- Broad Medical Research Program, USA (since 2004) 12- Swiss National Science Foundation, (Berne, Switzerland) (2003) 13- Egyptian Universities Promotion Committee (EUPC) (Basic Sciences; Zoology Committee); the 10 cycle. (Since 2008). Thesis Referee Duties (17 theses)  Medical University of South Carolina (1)  Tanta University (4 theses)  Cairo University (2 theses)  Dumiata University (3 theses)  Alexandria University (2 theses)  Banha University (1 thesis)  Suez Canal University (1 thesis)  Sadat Institute of Biotechnology (2 theses)  Assuit university (1 thesis)
  16. 16. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 16 CONFERENCES COMMITTEES (18 CONFERENCES) 1. Chairman, The first Annual Conference for Center of Excellence in Cancer Research: Next Generation in Cancer Research: Tanta University, Egypt, 24/2/2014. 2. Dubai Global summit and Expo on Vaccines & Vaccination. Dubai, UAE during September 28-30, 2015. 3. Session Chair, The 29th Annual Conference of Faculty of Medicine, Tanta University: Interdisciplinary Medicine. Funding raising session. Tanta University, Egypt. 18-20/3/2014. 4. Session Chair, 2013 Montreal International Forum on Immunology, Montreal, Canada, 19-20 October, 2013. 5. Coordinator, Biotechnology Session, the 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 6. Coordinator: The 3rd conference on Enhancing Scientific Research, Tanta University, Egypt, from 18-19 November 2012 (http://www.tanta.edu.eg/ar/Conf/Index.html). 7. Co-Chair, "Liver viruses and stem cells" session, The 8th Conference on Liver and Environment "Risks and solution": Towards a new strategy for control of liver diseases, Faculty of Medicine, Tanta University, 7-8 November, 2012. 8. Co-Chair, Hematology and Oncology Session, The 27th Annual Conference of Faculty of Medicine, Tanta University, 17-21 April, 2012. 9. Session Chair (Immunotherapy): TM's 1st World Immunology Online Conference, New York Time, March 16, 2012 10. Chairman, the First Conference of the Middle-Eastern Association for Cancer Research (MEACR), Tanta University Convention Center, 27-29/12/2011. 11. International Coordinator; The 3rd International Conference on Environmental Sciences organized by Tanta University, Egypt, November 2011. 12. Coordinator, International Communication, The 7th International Conference on Biological Sciences, organized by Botany and Zoology Departments, Faculty of Science, Tanta University, Egypt: 5-6, 12, 2012. 13. Co-Chair, "Immunology" session, The 7th International Conference on Biological Sciences, December 5-6 2012. 14. International Coordinator, Co-Chair, Plenary Session and The Junior Scientific Session: The 6th International Conference on Biological Sciences, organized by Botany and Zoology Departments, Faculty of Science, Tanta University, Egypt, November 2010. 15. Scientific Committee: The 6th International Conference on Biological Sciences, organized BY Botany and Zoology Departments, Faculty of Science, Tanta University, Egypt. 16. Scientific Committee: The 5th International Conference on Biological Sciences, organized BY Botany and Zoology Departments, Faculty of Science, Tanta University, Egypt 17. Scientific Committee, The 2nd Annual Meeting of Middle-Eastern Association for Cancer Research (MEACR 2012), Tunisia, 27-29, 12, 2011. 18. Coordinator and Co-Chair, Stem Cell Therapy: Egyptian Experiences: Faculty of Medicine, Tanta University, Egypt, 17/10/2011. Session Chair. 19. Coordinator, Development of Self and Exploring the Skills, Organized by Tanta Science Society, Faculty of Science, Tanta University, Egypt, October 18, 2011.
  17. 17. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 17 INVITED TALKS (73 talks) 1. Cancer versus immune therapy. International conference on Health & Life: Perspectives of Healthcare Industry in the Developing Countries; Challenges & Opportunities. Cairo University, from 1-3 November, 2014. 2. The role of cellular and molecular inhibitory mechanisms in anti-HCV immunity. Yemeni International Conference of Infectious diseases. University of Science and Technology Hospital, Sanaa, Yemen. 16-18 December, 2014. 3. Combinatorial anticancer chemotherapy and immunotherapy. Children Hospital Institute, Medical University of South Carolina, Charleston, SC, USA. November 12, 2014. (Invited by Endowed Prof. Singh, Department of Pediatrics, Department of Pediatrics, College of Medicine, Medical University of South Carolina, USA). 4. Anti-cancer Chemotherapy: To be or not to be. Division of Translational Research Department of Obstetrics and Gynecology, Medical College of Georgia, Georgia Regents University, USA. 25-11-2014. (Invited by Prof. Ayman Al-Hendy, Director, Division of Translational Research). 5. National and International research Projects, Faculty of Engineering, Tanta University, Egypt, 14/6/2014. 6. Center of Excellence in Research: Tanta University as a success story. Kafr Elsheikh University, Kafr Elsheikh, Egypt, 23-6-2014. 7. Multidisciplinary cooperation is a must for creating excellence in research: Tanta University as a success story. The Interdisciplinary and Multidisciplinary Studies and the Needs of the labor Market. Ain Shams University, Egypt, April 22-23, 2014. 8. Basic Concepts of Research proposal (Sponsored by Zewail’ Friends Society), Faculty of Medicine, Tanta University, Egypt, 20/1/2014. 9. Basic Concepts grants writing (Sponsored by Zewail’ Friends Society), Kafr El-Sheikh Convention Center, Kafr El-Sheikh, Egypt 12/3/2014 10. Combining adoptive cell therapy of innate and adaptive immune cells for optimal cancer immunotherapy. The 4th International Conference of Biological and Environmental Sciences, Mansoura University, Egypt 24-28 March 2014 11. Potential use of toll-like receptor (TLR) agonist for anticancer adoptive immunotherapy. The National Conference of Biochemistry, organized by the National Committee for Biochemistry. Ain Shams University, Egypt. April 1, 2014. 12. The toll-like receptor 3 agonist polyinosinic-cytidylic acid (poly(I:C)) targets natural killer cells with NK1.1+CD11b+CD11c+B220+Ly6G- phenotype. The 3rd World immunology Online Conference, March 25-27, 2014. 13. The Route to Research Fundraising: Tanta University as a Success Story: The 29th Annual congress of Tanta Faculty of Medicine: Multidisciplinary Medicine Era (Fund Raising Session), 17-20 March, 2014. 14. Accentuating the biological functions of G-CSF by forming G-CSF/anti-G-CSF antibody complexes without compromising CD8+ T cell immune responses: The 29th Annual congress of Tanta Faculty of Medicine: Multidisciplinary Medicine Era (Regenerative Medicine Session), 17-20 March, 2014. 15. Enhancing anti-cancer adoptive T cell therapy by triggering toll-like receptors signaling pathways: The 29th Annual congress of Tanta Faculty of Medicine: Multidisciplinary Medicine Era (Targeted Therapy Session), 17-20 March, 2014.
  18. 18. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 18 16. Myeloid cells as a double-edged sword in cancer immunotherapy. University of Montreal, Canada. October 21, 2013 17. Myeloid Cells as Controllers of Cancer Immunotherapy: The 11th Annual Congress of Medical Sciences under the theme of "Medical Research between Theory and Applications: Challenges and Innovations", December 17-19 th, 2013 at National Research Centre, Dokki, Cairo, Egypt. 18. Myeloid dells as a double-edge sword in cancer immunotherapy: Saint Justin Research Center Hospital, University of Montreal, Canada, 22/10/2013 19. Treatment with IL-12 induces acquisition of stem cell-like phenotype by early but not late melanoma-reactive CD8+ T cells that mediate tumor eradication upon adoptive transfer into a lymphopenic host. The Annual Conference of Arab Foundation of Biotechnology of Molecular Genetics and Stem cells: Stem Cell Applications and Human, Grand Haya Hotel, Cairo, Egypt, 20- 21 February, 2013. 20. Reprogramming tumor-reactive CD8+ T cells by IL-12 to acquire stem cell-like phenotype mediate tumor eradication upon adoptive transfer into a lymphopenic host. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 21. Development of a Novel Biopolymer Delivery System for DNA Vaccines and Adjuvants. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4- 8 March, 2013. 22. IMMUNOMODULATORY EFFECTS OF IL-12 RELEASED FROM POLY-N-ACETYL GLUCOSAMINE GEL MATRIX DURING SCHISTOSOMIASIS INFECTION. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 23. Myeloid-derived immunosuppressive cells in Cancer. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 24. Writing a fundable research proposal. Faculty of Science, Assuit University, Egypt, May 1-2, 2013. 25. Concept of Grant writing, Tanta University Staff Club, Tanta University, Egypt, May 22 and 25, 2013. 26. Concept of Grant writing: STDF as a model, Faculty of Science, Suez University, Egypt, May 22 and 25, 2013. 27. The use of Endnote in citation and bibliography. ICTP center, Tanta University Project Management Unit, Tanta University, March 23, 27, and 30, 2013. 28. National and International funding sources for competitive research projects. Faculty of Nursing, Tanta University, Egypt, March 24, 2013. 29. How to turn your research idea into a fundable project. Faculty of Science, Sue University, Egypt, April 29, 2013. 30. The Use of Animals in Research, a workshop organized by Egyptian-German Society of Zoology, held at Faculty of Science, Cairo University, Cairo, Egypt, December 30, 2012. 31. Role of immune regulator cells in development of cancer: The 5th Annual Histopathology Course. International Medical Center (IMC), February 25th to March 3th, 2013. 32. Dendritic cells in renal disease: The 5th Annual scientific Conference of IMC Updates in nephrology and renal transplant. February 25th to March 3th, 2013. 33. International Publications and Intellectual property Right to Faculty Members at Faculty Agriculture, Kafr Elsheikh University, December 19, 2012.
  19. 19. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 19 34. Writing Competitive Research Project to Faculty Members at Faculty and Leadership Development Center (FLDP program), Project Management Unit, Kafr Elsheikh University, December 4, 2012. 35. A Novel escape mechanism of cancer from immunotherapy, A plenary lecture presented at The 7th International Conference on Biology, Tanta University, 5-6 December, 2012. 36. Cellular and Molecular Tumor Markers: The 1st Scientific Conference of Laboratory Diagnosis, 2 November 2012. 37. Immunotherapy of HCC: The 8th Conference on Liver and Environment "Risks and solution": Towards a new strategy for control of liver diseases, Faculty of Medicine, Tanta University, 7-8 November, 2012. 38. Novel Immunotherapeutic Strategies to Cure Cancer, Zewail City of Science and Technology, September 3, 2012 39. Stem cell-derived myeloid cells and the dysfunction in their maturation. A plenary lecturer at the Medical tests workshop, Faculty of Science, Alexandria University, Egypt, July 18, 2012. 40. Anti-cancer chemo-immunotherapy: Learned preclinical lessons for potential clinical application. Laser Institute, Cairo University, Egypt. 14/6/2012. 41. How to turn your research idea into a fundable project. Faculty of Science, Cairo University, Egypt, May 27 and 4 June, 2012. A workshop organized by Egyptian-German Society of Zoology. 42. How does chemotherapy benefit cancer immunotherapy? TM's 1st World Immunology Online Conference, New York Time, March 16, 2012. 43. Egypt: The beating heart of the Middle East. Key Lab. Infection and Immunity, Center of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, February 24, 2012. 44. Altering Myeloid cells by Chemotherapy: Implications for Cancer Immunotherapy. Department of Biochemistry and Molecular Cell Biology, Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China, February 21, 2012. 45. Potential strategies to enhance application of anti-cancer adoptive T cell immunotherapy. Biotherapy Center of the First Affiliated Hospital & the Department of Bioengineering, Zhengzhou University, China, February 13, 2012. 46. Efficacy of Combinatorial anti-cancer chemotherapy and immunotherapy: A central role of dendritic cells. Key Lab. Infection and Immunity, Center of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, February 9th, 2012. 47. Myeloid-derived suppressor cells: A limited factor for anti-tumor immunity. Key Lab. Infection and Immunity, Center of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, February 16th, 2012. 48. Rebounding of Dendritic Cells Post Chemotherapy: Implication for cancer immunotherapy. Vaccines and Vaccination 2011, Philadelphia, USA, 22-24 November, 2011. 49. Optimizing Higher Education by Merging Teaching and Research skills. The 1st International conference on Education Development organized by The 5th Meeting of Egyptian Association Abroad for Enhancement and Development of Education in Egypt (October 29-31, 2011). Cairo University, October 31, 2011. 50. How Does Chemotherapy Enhance Adoptive Anti-Tumor T Cell Therapy? Department of Microbiology and Immunology, University of Miami, May 26, 2011. 51. Laboratory Notebook Policy: Center for Academic Development, Tanta University, Egypt,
  20. 20. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 20 15/3/2011. 52. Tools for Project Management: Center for Academic Development, Tanta University, Egypt, 23/3/2011. 53. Self Experience in The Use of Adoptive T Cell Transfer in Anti-cancer Therapy: The Annual Meeting of German-Egyptian Society of Zoology, Bani Sweif University, Egypt, February, 2011. 54. Competitive Research Status at Tanta University; Faculty of Medicine, Tanta University, Egypt, December, 2010. 55. The concept of Grant Writing: STDF as A Model; Faculty of Pharmacy, Tanta University, Egypt, December, 2010. 56. The concept of Grant Writing: STDF as a model grant; Faculty of Dentistry, Tanta University, Egypt, September 22, 2010. 57. How to write a competitive research proposal: Mubarak City for Scientific Research and Technology and Applications, Alexandria, Egypt, November, 2010. 58. Writing a competitive research proposal: Faculty of Science, Tanta University, Egypt, May, 2010. 59. How to write a competitive research proposal: Faculty of Science, Tanta University, Egypt, May, 2010. 60. How to write a competitive research proposal: Faculty of Science, Alexandria University Damanhour Branch), Egypt, 28 June, 2010. 61. How to write a competitive research proposal: A focus on Science and Development Fund (STDF). Faculty of Science, Banha University, Banha city, Egypt, 27 June, 2010. 62. Immunosuppressive myeloid cells and anti-tumor immunity: Mubarak City for Scientific Research and Technology and Applications, Alexandria, Egypt, June, 2010. 63. The potential application of the immunomodulatory adjuvant poly(I:C) in anti-tumor immunity: Mubarak City for Scientific Research and Technology and Applications, Alexandria, Egypt, June, 2010. 64. Application of the toll-like receptor 3 agonist poly(I:C) as an adjuvant for cancer immunotherapy. Georgia Institute of Technology. School of Chemistry and Biochemistry. Atlanta, Georgia, March 8, 2010 65. Fostering Research in the Research Institutes in Egypt. Invitation through the TOKTEN Project of the Egyptian Academy of Scientific Research and Technology (ASRT) to participate in The 2nd International Conference for Enhancing Scientific Research held at Tanta University, Egypt, March 4 - 5, 2009. 66. Vivarium and Institutional Regulation: A Must For A Successful Research. Tanta University, Tanta, Egypt. November 25, 2008. 67. Chemotherapy: Friend or foe for cancer Immunotherapy. Tanta University, Tanta, Egypt. November 5, 2008. 68. Chemotherapy: Friend or foe for cancer Immunotherapy: Mubarak City for Science and Technology, Alexandria, Egypt. November 24, 2008. 69. Immunomodulatory and immunotherapeutic potentials of Nigella sativa, the black seed. The 1st International Conference on Prophetic Medicine, Abha Private Hospital, Abha, Saudi Arabia, King Saudi Arabia, February, 2008. 70. Lymphodepletion: A bad for good immunotherapy: Internal Speaker, Cancer Immunology and Immunotherapy Lecture Series, Hollings Cancer Center, Medical University of South Carolina, Charleston, USA. February 2008.
  21. 21. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 21 71. Development of Molecular Cancer Therapies: From Bench to Bedside of Cancer Vaccines. Department of Microbiology and Immunology, Medical University of South Carolina, USA. 72. Optimizing Cancer Immunotherapy By Creating Beneficial Host Microenvironments: Department of Surgery, Medical University of South Carolina, USA; June 11, 2007. 73. Novel Adjuvant Approaches for Optimization of Peptide-based Cancer Vaccines: College of Medicine and Health Sciences, United Arab Emirates University, United Arab Emirates, Al-Ain, United Arab Emirates, 30 May, 2004 74. Optimization of T cell responses to vaccination: Applications for cancer immunotherapy. Permanent Scientific Committee for Professorship Promotion, Ministry of Higher Education, Ain Shams University, Egypt, November 15, 2006. 75. Influence of Female Sex Hormones on Immune Responses. Center for Biomedical Physics, Temple University School of Medicine, Philadelphia, Pennsylvania, USA. 24 November, 2000. SABBATICAL LEAVE (10 LEAVE) 1. USA: Visiting Professor, Department of Microbiology and Immunology, Medical University of South Carolina, USA from September 9, 2014-December 8, 2014. 2. USA: Visiting Professor, Department of Microbiology and Immunology, Medical University of South Carolina, USA from 29/1/2013 to 20/2/2013 3. China: Key Lab. Infection and Immunity, Center of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, February 24, 2012. This scientific mission was a Visiting Professorship supported mutually by the Third World Academy of Sciences (TWAS) and the Chinese Academy of Sciences (CAS). 4. USA: Surgery Department and Hollings Cancer Center, Medical University of South Carolina, USA from 6/2001 to 6/2002. This scientific mission was a Post-Doctoral Fellowship supported by R01 grant from National Cancer Institute, National Health Institute, USA. 5. USA: Surgery Department and Hollings Cancer Center, Medical University of South Carolina, USA from 6/2002 to 6/2010. This is an Assistant Professorship supported by R01 grant from National Cancer Institute, National Health Institute, USA. 6. Japan: Department of Immunology, Medical Institute of Bioregulation, Kyushu University, Japan. PhD Researcher from 10/1992 to 12/1994. This scientific mission was supported by a 27-month scholarship from the Ministry of Higher Education and Scientific Research, Egypt. 7. Japan: Department of Immunology, Medical Institute of Bioregulation, Kyushu University, Japan from 10/1997 to 1/1998. This scientific mission was a Research Non-Degree Student (Monbukagakusho Scholarship) supported by a 15-month scholarship from the Ministry of Education, Culture, Sports, Science and Technology, Japan. 8. Japan: Department of Immunology, Medical Institute of Bioregulation, Kyushu University, Japan from 1/1999 to 3/2001. This scientific mission was a Research Non-Degree Student (Monbukagakusho Scholarship) supported by a 3-year scholarship from the Ministry of Education, Culture, Sports, Science and Technology, Japan. I completed 2 years only and moved to USA. 9. Italy: Tumori Instituti Pascali. This scientific mission was a Junior Researcher Travel Award from Tumori Instituti Pascali to attend HLA and Tumors workshop, Napoli, Italy from December 2-6, 1996.
  22. 22. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 22 10. Italy: Tumori Instituti Pascali. This scientific mission was a Junior Researcher Travel Award from Tumori Instituti Pascali to attend Immunosuppressive Drugs & the Immune System, Napoli, Italy from 2-11 Nov., 1994. WORKSHOPS (9 International and 15 nationals) INTERNATIONAL 1. Reunion of the Educational Institute for Responsible Research on Infectious Diseases: Ensuring Safe Science in the 21 Century, an international educational workshop held from April 20-22, 2013, Amman, Jordan, sponsored by the American National Academy of Sciences. 2. The Educational Institute on Responsible Research on Infectious Diseases: Ensuring Safe Science in the 21th Century sponsored and organized b U.S. National Academy of Sciences, Aqaba, Jordan, 8-13 September, 2012. 3. Grantsmanship workshop. Organized by National Institute of Health with Dr. Ronald Geller, Health Research Associates. Medical University of South Carolina, Charleston, SC, USA. Part 1, March 11, 2003; Part 2: April 29, 2003; and Part 3: May 20, 2003. 4. Tumor Immunology Primer: Organized by Society for Biological Therapy. Hilton La Jolla Torrey Pines, San Diego, CA, USA, November 7, 2002. 5. Human Subject Assurance Online Training Modules. Intranet work, Medical University of South Carolina, Charleston, SC, USA. August 19, 2002. 6. OSHA Requirements: Hazard Community/Hazardous waste disposal, Blood borne pathogen standard, Tuberculosis, Fire safety and Ergonomics. An On line workshop at Local network, Medical University of South Carolina, Charleston, SC, USA, Dec. 13, 2001. 7. The Winter Advanced Course for Immunology & Infectious Diseases (WACIID)'1994. Tokyo, Japan, Feb. 13-16, 1994. 8. HLA and Tumors. Tumori Instituti Pascali, Napoli, Italy, Dec. 2-6, 1996. 9. Immunosuppressive Drugs & the Immune System. Tumori Instituti Pascali, Napoli, Italy, 2-11 Nov., 1994. National 1. Writing Scientific Proposal Post Doc: a workshop organized by Tanta University Competitive Project Unit and DAAD Kairo Akademie (Cairo), December 16, 2012, Tanta University Development Center, Tanta University, Tanta, Egypt 2. How to write a TEMPUS proposal: December 10, 2012, Faculty of Medicine, Tanta University, Egypt. 3. Training of the Trainers (TOT) within the DAAD Kairo Akademie on 16-18 and 22 October 2012 at the premises of "GAAD Cairo" by Dr. Claudia Gross, DAAD Kairo Akademie, Cairo, Egypt. 4. Ethics in Research. Organized by Egyptian-German Society of Zoology, Cairo University, Egypt. Faculty of Science, Tanta University, April 2012, Egypt. 5. Critical Thinking Skills: A part of the Faculty Leadership and Development Program (FLDP) from 21 to 23 January, 2006, Tanta University Development Center, Tanta University, Tanta, Egypt.
  23. 23. Curriculum Vitae Mohamed Labib Salem, PhD November, 2014 23 6. Preparing A Draft Research Paper: A part of the Faculty Leadership and Development Program (FLDP), Kafr El-Sheikh University Development Center, Tanta University, Kafr El-Sheikh, from 13 to 15 November 2006, Egypt. 7. Academic Leadership: A part of the Faculty Leadership and Development Program (FLDP), Kafr El-Sheikh University Development Center, Tanta University, Kafr El-Sheikh; from 16 to 19 November 2006, Egypt. 8. Quality Assurance and Accreditation: A part of the Faculty Leadership and Development Program (FLDP), Tanta University Development Center, Tanta University, Tanta, from 24 to January 25, 2006, Egypt. 9. Curriculum Design: A part of the Faculty Leadership and Development Program (FLDP), Tanta University Development Center, Tanta University, Tanta, 18 to January 19, 2006, Egypt. 10. Ethics in Scientific Research: A part of the Faculty Leadership and Development Program (FLDP), Tanta University Development Center, Tanta University, Tanta, 11/2005, Egypt. 11. Developing Skills in Molecular Pathology. Faculty of Medicine, Zagazig University, April 2-3, 1997, Egypt. 12. Molecular Pathology, Flow Cytometry, Image Cytometry, In Situ hyperidization, PCR and ELISA Techniques. Pathology Department, Faculty of Medicine, Zagazig University, May 6-7, 1997, Egypt. 13. Educational Program for Teaching. Graduate Studies: Faculty of Education, Tanta University, June 1995, Egypt. 14. English Course for Graduate studies. Faculty of Education, Tanta University, Nov. - Dec., 1994, Egypt. 15. International English Language Testing System (IELTS) course, Center number EG002, Writing Examiner Number EG002/02/89, Speaking Examiner Number EG002/02/89, British Council, Alexandria, August 24, 1992, Egypt. SEMINARS (18 Int. and 16 National) INTERNATIONAL 1. The 40th edition of the Arab Health Exhibition, Dubai International Convention & Exhibition Centre, Dubai, United Arab Emirates, 26 - 29 January 2014 2. 2010 HCC Spring Symposium: Early Drug Development: Making it Happen: Medical University of South Carolina, Hollings Cancer Center, Charleston, SC, USA, March 12, 2010. 3. The 6th Annual Hematological Malignancies Symposium. Medical University of South Carolina, Charleston, SC, USA, February 19, 2010. 4. The 3rd Annual Ovarian Cancer Research Symposium: Medical University of South of South Carolina, SC, USA, March, 2007. 5. The 5th Annual Hematological Malignancies Symposium: Medical University of South Carolina, Charleston, SC, USA, February 6, 2009. 6. Research Project Grants (RPG) Retreat: Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA. January 24, 2009.
  24. 24. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 24 7. Head and Neck Multidisciplinary Research Symposium. Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA, April 19 , 2007. 8. The 3rd Annual Hematological Malignancies Symposium. Riviera Theatre & Conference Centre, Charleston, SC, USA. February 13, 2007. 9. Tenure Mentoring Symposium: Cosponsored by Office of the provost and the Faculty Senate, Medical University of South Carolina, SC, USA. Friday, May 12, 2006. 10. Immunotherapy of Cancer X: Tumor Vaccine and Cell Therapy Working Group (TVACT). Washington, DC, Convention Center USA, April, 2006. 11. Cancer Chemoprevention: Bridging Statewide Partnerships: The Science Driving the Latest Cancer Chemoprevention Strategies. The Citadel Holliday Alumni Center, Medical University of South Carolina, SC, USA, March 16-17, 2006. 12. Immunotherapy of Cancer IX: Tumor Vaccine and Cell Therapy Working Group (TVACT). Washington, DC, Convention Center, USA, April, 2005. 13. Translational Therapeutics Spring Symposium: Hollings Cancer Center, Citadel Alumni House, Charleston, SC, USA, March. 11, 2005. 14. The 1st Annual Hematological Malignancies Symposia. Medical University of South Carolina, Charleston, SC, USA, Feb. 24, 2005. 15. The Translational Therapeutics Spring Seminar, Citadel Holliday Alumni Center, Charleston, SC, USA, March 11, 2005. 16. Immunotherapy of Cancer XI: Tumor Vaccine and Cell Therapy Working Group (TVACT). Orlando, Florida, USA, March 26, 2004. 17. Gene Regulation in Cancer. Hollings Cancer Center, Medical University of South Carolina, USA, March 12, 2004. 18. Modulation of Angiogenesis and Apoptosis in Cancer Therapy. Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA, March 14, 2003. National 1. The 34th Scientific Annual meeting of the Egyptian Society of Hematology, Marriot Hotel, Cairo, Egypt, 9-10 January, 2013. 2. The 27th Annual Conference of the Faculty of Medicine, University of Tanta: The Revolution and Medicine, Tanta University, Egypt, April 28, 2012. 3. The first Annual Conference on the Mediterranean anemia: A focus on Thalasemia. Faculty of Mecicine, Tanta University, Egypt, July 14, 2012. 4. Stem Cell Therapy: Egyptian Experiences: Faculty of Medicine, Tanta University, Egypt, 17/10/2011. 5. Research and Industry: From Lab to Reality: Bibliotheica Alexandrina, Alexandria, Egypt, Thursday 28 July, 2011. 6. Fulbrighters Face Egypt Scientific Challenge, The City of Scientific Research and Technology, Alexandria, Burg Al-Arab, Egypt, July 7, 2011. 7. Closing Conference & Projects’ Exhibition of RDI Program (Phase I), Semiramis Intercontinental Hotel, Cairo, Egypt, June 20, 2011. 8. The Internationalization of the University System in Egypt. Sponsored by Ministry of Higher Education and Research, Egypt, and Italian Embassy in Cairo. Central Library, Cairo University, Egypt, 19-20/10, 2010.
  25. 25. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 25 9. TEMPUS Program (Erasmus Mundes): Flow-by-Flow EU-Egypt Bridge Building, Sponsored by Ministry of Higher Education, Alexandria University, Alexandria, Egypt, June 5, 2010. 10. The 1st NAQAAE Quality Assurance (NAQAAE) Advisory Board meeting: Sponsored by National Authority of Quality Assurance and Accreditation in Egypt (NAQAAE): Smart Village and The Grand Hayatt Hotel (Cornish El Neil), Cairo, Egypt, 9-10 June, 2010. 11. Poem Context: Organized by Cultural Affairs of Faculty of Science, Tanta University on the honor of the poet Mrs. / Alya Alhjaar Student, Faculty of Science, Tanta University, Egypt, February - 2000. 12. Zinc deficiency in Egypt and its impact on human health: Organized by the Egyptian Society for Diseases of The Digestive System and Malnutrition in Children, Faculty of Medicine, Tanta University, Egypt, Thursday, 17 February 2000 13. Environmental Variability of Natural Wildlife. Faculty of Science, Tanta Univ., Under Cure of Ministry of Environmental affairs, Egypt, May 10, 1997. 14. Biological Diversity: in conjunction with the Ministry of Environmental, Faculty of Science, Tanta University, Egypt 10/5/1997. 15. Molluscicidal Evaluation from the Plant Origin in the Control of Schistosoma mansoni snails. Theodor Bilharz Institute, Cairo, Egypt, May 27, 1996. 16. Cultivation and Molluscicidal Application of Ambrosia martima Plant. Building of Gharbia Governorate, Egypt, December 23, 1995. CONFERENCES (56 Int. and 27 National) INTERNATIONAL 1. Frequencies of MDSC in Egyptian patients with chronic HCV infection undergoing treatment with IFN-α therapy. Montreal 2013 international forum on Immunology, Montreal Canada, October 20, 2013. 2. Frequencies of circulating myeloid derived suppressor cells and dendritic cells in Egyptian patients with chronic Hepatitis C Virus infection undergoing treatment with IFN-a-based therapy. Journal for Immunotherapy of Cancer 2013, 1(Suppl 1):P248 (http://www.immunotherapyofcancer.org/content/1/S1/P248). From Society for Immunotherapy of Cancer 28th Annual Meeting National Harbor, MD, USA. 8-10 November 2013. 3. Increases in the frequency of myeloid-derived immunosuppressor cells in Egyptian patients with chronic hepatitis C virus. The 2nd Int. Conference on Viral Hepatitis. New York, NY, USA, 26-27, 3, 2012. 4. Rebounding of dendritic cells post chemotherapy: implication for cancer immunotherapy.Vaccines and Vaccination 2011, Philadelphia, USA, 22-24 November, 2011. 5. Reversing Aged Phenotype of T Cells by In Vitro Conditioning with TLR Agonists. Annual Meeting of American Association of Cancer Research (AACR), Orlando, FL, USA, April 12-16, 2011. 6. Potential use of toll-like receptor ligands to condition T cells for adoptive immunotherapy. The 14th International Congress of Immunology (ICI 2010), Kobe, Japan, August 22-27, 2010 7. Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a FLT3L-dependent expansion of dendritic cells. Frontiers in Basic Immunology; Sponsored by the
  26. 26. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 26 Center of Excellence in Immunology, National Institutes of Health,, Bethesda, MD, USA; October 1-2, 2009. 8. vivo activity of early cytokine conditioned effector CD8+ T cells inversely correlates with their anti-tumor activity in vivo. The 96th American Association of Immunologist Annual Meeting, Seattle, Washington, USA, May 8-12, 2009. 9. Addition of toll-like receptor agonists during antigen presentation in vitro and in vivo augments antigen-specific CD8+ T cells responses: Implication for adoptive T-cell therapy. 8th Annual Scientific Research Retreat. Medical University of South Carolina, Charleston, SC, USA, December 5, 2008. 10. Dendritic cells expand during the restoration phase post cyclophosphamide treatment and mediate robust anti-tumor responses upon their stimulation with TLR3 agonist. Cancer Immunology and Immunotherapy: Realizing the Promise. National Institutes of Health, Bethesda, MD, USA, September 11-12, 2008. 11. In vitro conditioned "early" but not "late" effector CD8+ T cells benefit from transient lymphopenia resulting in enhanced anti-tumor activity. (The FASEB Journal. 2008;22:1077.20. The 95th American Association of Immunologist Annual Meeting, San Diego, CA, USA 2008. 12. In vitro conditioned "early" but not "late" effector CD8+ T cells benefit from transient lymphopenia resulting in enhanced anti-tumor activity. 2008 Hollings Cancer Center Spring Symposium: Focus on cancer Immunology and Immunotherapy. Hollings Cancer Center, Charleston, SC, USA, March 13-14, 2008. 13. Nov-002, a novel formulation of oxidized gulathione enhances antigen-specific CD8+ T cell responses after cyclophosphamide (CTX) by downregulation of iNOS in myeloid derived suppressor cells (MDSC). 2008 Hollings Cancer Center Spring Symposium: Focus on cancer Immunology and Immunotherapy. Hollings Cancer Center, Charleston, SC, USA, March 13-14, 2008. 14. Dendritic cells expand post cyclophosphamide therapy and mediate robust anti-tumor responses upon their stimulation with TLR3 agonist. Tumor vaccine & Cell Therapy (TVACT) Working Group: Immunotherapy of Cancer XII, San Diego, California, USA, April 11, 2008. 15. Immunomodulatory and immunotherapeutic potentials of Nigella sativa, the black seed. The 1st International Conference on Prophetic Medicine, Abha Private Hospital, Abha, Saudi Arabia, King Saudi Arabia, February, 2008. 16. Mediation of cyclophosphamide induced systemic expansion of myeloid cells by Flt3L. The Annual Meeting of American Association of Immunologists (AAI), Miami Beach Convention Center, Miami, Florida, USA. May 18-22, 2007. 17. The TLR3 agonist poly (I:C) acted directly on mouse CD8 T cells and augmented their antigen- specific responses upon adoptive transfer into naïve recipient mice. The 96th Annual Meeting of American Association of Immunologists (AAI), Miami Beach Convention Center, Miami, Florida, USA. May 18-22, 2007. 18. Circulating Levels of CD4+CD25+ T cells Correlate with Clinical Cancer Stage and Inversely Correlate with CD8 T cells. The 96th Annual Meeting of American Association of Immunologists (AAI), Miami Beach Convention Center, Miami, Florida, USA. May 18-22, 2007. 19. Circulating Immature Myeloid Cells (ImC) Levels Correlate with Clinical Cancer Stage and Cyclophosphamide (CTX) Treatment. The 96th Annual Meeting of American Association of Immunologists (AAI). Miami Beach Convention Center, Miami, Florida, USA. May 18-22, 2007.
  27. 27. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 27 20. Poly-N-acetyl glucosamine gel (F2 gel) matrix is a novel non-viral delivery system that augments the efficacy of CD8+ T cells responses to vaccination with naked DNA plasmid encoding HIV-1 p37. Cancer Drug Discovery and Development: Bridging Academic and Industry Partnerships; Spring Symposium. Kiawah Island, SC, USA; Marc 23-24, 2007. 21. Paracrine delivery of low non-toxic levels of IL-12 from poly-N-acetyl glucosamine gel (F2 gel) matrix lowered the liver and lung fibrosis induced by Schistosoma mansoni eggs. The 13th International Congress of Immunology, Rio De Janeiro, Brazil, 21-25, 8, 2007. 22. Cyclophosphamide treatment leads to striking expansion of functional dendritic cells in vivo: Implications for cancer immunotherapy. 98 Annual Meeting for American Association of Cancer Research (AACR). Los Angeles, CA, USA. April 14-18, 2007. 23. Circulating myeloid derived suppressor cells in breast cancer patients correlate with clinical cancer stage and cyclophosphamide treatment: implications for cancer immunotherapy. San Antonio Breast Cancer Symposium. San Antonio, TX, USA. May 31, 2007. . 24. Increased Levels of Circulating Immature Myeloid Cells (ImC) Correlates with Advanced Cancer Stage and Doxorubicin/Cyclophosphamide Treatment. The 6th Annual Research Retreat. Citadel, Charleston, SC, USA. November 17th, 2006. 25. Vaccination using Toll-like receptor ligand (TLRL)-primed dendritic cells and TLR3L poly I:C administration leads to an augmentation of antigen-specific memory CD8+ T cell responses. The 97th Annual Meeting for American Association of Cancer Research (AACR). Washington DC, USA, April 1-5, 2006. 26. Sustained generation and survival of antigen-specific CD62L +CD8+ T-cells though in vitro conditioning with interleukin-12: Implications for anti-tumor adoptive immunotherapy. The 97th Annual Meeting for American Association of Cancer Research (AACR). Washington DC, USA, April 1-5, 2006. 27. Cyclophosphamide Preconditioning Enhances The Antigen-specific CD8 T Cell Responses to Peptide Vaccination: Evidence of Enhanced Innate Immunity and Induction of A Beneficial Cytokine Milieu. Tumor vaccine & Cell Therapy (TVACT) Working Group: Immunotherapy of Cancer XI, Garden Grove, California, USA, April 15, 2005. 28. Vaccination using Toll-like receptor ligand (TLRL)-primed dendritic cells and TLR3L poly I:C administration leads to an augmentation of antigen-specific memory CD8+ T cell responses Annual Research Retreat, Citadel, Charleston, SC USA. November 18th, 2005. 29. Cyclophosphamide preconditioning enhances the antigen-specific CD8 T cell responses to peptide vaccination: evidence of enhanced innate immunity and induction of a beneficial cytokine milieu Annual Research Retreat, Citadel, Charleston, SC, USA. November 18th, 2005. 30. Vaccination using Toll-like receptor ligand (TLRL)-primed dendritic cells and TLR3L poly I:C administration leads to an augmentation of antigen-specific memory CD8+ T cell responses Annual Research Retreat, Citadel, Charleston, SC USA. November 18th, 2005. 31. Temporal induction of a beneficial inflammatory cytokine milieu relative to peptide vaccination is crucial for the optimal adjuvanticity of the TLR3 agonist polyinosinic-polycytidylic acid (Poly I:C). 96 Annual Meeting for American Association of Cancer Research (AACR). Anaheim, California, USA, April 16-21, 2005. 32. Cyclophosphamide preconditioning enhances the antigen-specific CD8 T Cell responses to peptide vaccination: Evidence of Enhanced Innate Immunity and Induction of A Beneficial
  28. 28. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 28 Cytokine Milieu. The Annual Meeting of the American Association of Immunologists (AAI). San Diego, CA, USA. April 2-6, 2005. 33. 5-aminoimidazole-4-carboxymide ribonucleoside: A novel Immunomodulator in experimental autoimmune encephalomyelitis. The Annual Meeting of the American Association of Immunologists (AAI), San Diego, CA, USA, April 2-6, 2005. 34. Retrovirally-modified T cells persist after adoptive transfer but exhibit discordant gene expression associated with a lack of therapeutic ability. The Annual Meeting of the American Association of Immunologists (AAI), San Diego, CA, USA, April 2-6, 2005. 35. Mediation of the adjuvant effect of the toll-like receptor 3 (TLR3) agonist by induction of a rapid beneficial inflammatory cytokine milieu. The 7th International Conference of Anticancer Research. Corfu, Greece, 25-30 October 2004. 36. Defining the Mechanisms underlying Inhibition of breast cancer carcinogenesis by EpCAM gene silencing. 7th International Conference of Anticancer Research. Corfu, Greece, 25-30 October 2004. 37. Sustained release of interleukin-12 from a novel delivery system using a poly-N-acetyly glucoseamine-based polymer matrix enhances peptide-based cancer vaccine. Tumor Vaccine & Cell Therapy (TVACT) Working Group: Immunotherapy of Cancer X. Orlando, Florida, USA, March 26, 2004. 38. Novel non-viral delivery system enhances the efficacy of DNA vaccines targeting cytotoxic T lymphocytes. 2004 Annual Research Retreat, Charleston, SC, USA, November 11, 2004. 39. Double-stranded RNA (dsRNA) danger motif is potent adjuvant to accentuate peptide-based cancer vaccine by bridging innate and adaptive immunity. 95 Annual Meeting for American Association of Cancer Research, Orange County Convention Center, Orlando, FL, USA, March 27-31, 2004. 40. Sustained release of interleukin-12 from a novel delivery system using a poly-N-acetyly glucoseamine-based polymer matrix enhances peptide-based cancer vaccine. Recent concepts in cancer management. Helnal Paletine Hotel, Montaza Palace, Alexanderia, Egypt, 22-24 Oct, 2003. 41. Paracrine release of IL-12 from a modular peptide-based cancer vaccine enhances the antigen- specific CD8 T cell response. 2nd Annual Research Retreat, Wild Dunes, Charleston, SC, USA Page:48, August 23 , 2002. 42. Paracrine release of IL-12 from a modular peptide-based cancer vaccine enhances the antigen- specific CD8 T cell response. 93th Annual Meeting for American Association of Cancer Research, San Francisco, CA, USA, April 6-10, 2002, Abstract#3002, page:606. 43. Persistence and function of adoptively transferred retrovirally-transduced T cells in vivo. 93th Annual Meeting for American Association of Cancer Research, San Francisco, CA, USA, April 6- 10, 2002. Abstract#2193, page:441. 44. Subcutaneous treatment with linoleic acid suppresses the growth of EL4 thymoma in mice through augmentation of Cytolysis of CD8 and production of IFN-. The Autumn Conference of Immunology, Marriot Hotel, Chicago, USA, 19-21 Nov., 2000, Abstract no. 48, Page: 25. 45. Double-stranded RNA (dsRNA) danger motif is potent adjuvant for accentuating peptide-based vaccine by bridging innate and adaptive immunity. 3rd Annual Research Retreat, Wild Dunes, Charleston, SC, USA, December 23rd, 2003. 46. 3rd 3Annual Research Retreat, Wild Dunes, Charleston, SC, USA, December 23 , 2003, PP. 67.
  29. 29. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 29 47. Double-stranded RNA (dsRNA) Danger Motif Bridges Innate and Adaptive Immunity and Is Potent Adjuvant for Accentuating Peptide-Based Cancer Vaccine. The 3rd Annual Research Retreat, Wild Dunes, Charleston, SC, USA, December 23, 2003. 48. Mechanisms of enhanced antigen-specific T cell response to a novel peptide-based cancer vaccine: Paracrine release of interleukin-12 results in enhancement of antigen presentation and appears to be interferon-gamma dependent. 94th Annual Meeting for American Association of Cancer Research, Washington Convention Center, Washington, DC, USA, July 10- 14, 2003. 49. Exploring the interplay between innate and adaptive immunity: polyinosine: cytosine (Poly I:C) enhances the antigen-specific T cell response to a peptide-based cancer vaccine. Basic Aspects of tumor immunotherapy (C5), Keystone, Colorado, Denver, USA, Feb 17-23, 2003.. 50. A Role for Peripheral Blood Fibrocytes in African trypanosomiasis and Lyme disease. South African Veterinary Association, Cape Town, South Africa, 74(3):87-101, 2003. 51. Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2). J. Immunother., 25(6):S35, 2002. 17th annual Scientific Meeting of the Society for Biological Therapy, La Jolla, California, USA, November 7-10, 2002 52. Systemic administration of IL-15 augments the antigen-specific primary CD8+ T cell response following vaccination. J. Immunotherapy, 25(6):S18, 2002. 17th annual Scientific Meeting of the Society for Biological Therapy, La Jolla, California, USA, November 7-10,2002. 53. Subcutaneous treatment with linoleic acid suppresses the growth of EL4 thymoma in mice through augmentation of Cytolysis of CD8 and production of IFN-α. The Autumn Conference of Immunology, Abstract no. 48, Page: 25, Chicago, USA, 19-21 Nov., 2000. 54. Immunotoxicity of cadmium chloride in mice: Time course study. "HLA and Tumours", Italy, Naples, Dec. 2-6, 1996. 55. -estradiol-induced inhibition of macrophages function during Listeria monocytogenes infection. The Winter Advanced Course for Immunology and Infectious Diseases (WACIID)'1994". Tokyo, Japan, Feb., 13-16, 1994. 56. Immunoregulatory influence of β-estradiol on Macrophage Functions. Proc. Jap. Soc. Immunol., Kyoto, Japan, Nov. 1994. 57. Influence of -estradiol on Listeria monocytogenes infection. Japanese Soc. for Microbiol., Tokyo, Japan, March 28-31, 1994 National 1. Myeloid-derived Suppressor Cells in Egyptian Patients with Chronic HCV Infection. The 5th Int. Conference of Virology: Viruses and potential hazard to human, animal and plants. The Role of National & International Organization. Hurghada, Egypt, December 9-12, 2014. 2. Acute lymphocytic leukemia and the regulatory arms of immune system. The 12th Annual Congress of Medical Sciences. National Research Center, Cairo. 17-18 December 2014. 3. Treatment with IL-12 induces acquisition of stem cell-like phenotype by early but not late melanoma-reactive CD8+ T cells that mediate tumor eradication upon adoptive transfer into a lymphopenic host. The Annual Conference of Arab Foundation of Biotechnology of Molecular Genetics and Stem cells: Stem Cell Applications and Human, Grand Haya Hotel, Cairo, Egypt, 20-21 February, 2013.
  30. 30. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 30 4. Reprogramming tumor-reactive CD8+ T cells by IL-12 to acquire stem cell-like phenotype mediate tumor eradication upon adoptive transfer into a lymphopenic host. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 5. Development of a Novel Biopolymer Delivery System for DNA Vaccines and Adjuvants. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 6. Immunomodulatory effects of IL-12 released from poly-B-acetyl glucosamine gel matrix during schistosomiasis infection. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 7. Myeloid-derived immunosuppressive cells in Cancer. The 28th Annual congress of Tanta Faculty of Medicine: Quality and Medicine, Tanta University, Egypt, 4-8 March, 2013. 8. Anti-schistosomal and anti-tumor responses to mutual interaction between cancer and infection. The 1st Annual Meeting of the Middle-Eastern Association for Cancer Research (MEACR 2011). Tanta University, Egypt, 27-28, 12, 2011. 9. Increases in the frequency of myeloid-derived immunosuppressor cells in Egyptian patients with chronic hepatitis C virus. The 1st Annual Meeting of the Middle-Eastern Association for Cancer Research (MEACR 2011). Tanta University, Egypt, 27-28, 12, 2011. 10. The toll-like receptor 3 agonist polyinosinic-cytidylic acid (poly(I:C)) targets natural killer cells with NK1.1+CD11b+CD11c+Ly6G-B220+ phenotype. The 1st Annual Meeting of the Middle- Eastern Association for Cancer Research (MEACR 2011). Tanta University, Egypt, 27-28, 12, 2011. 11. Intermittent Prolonged Fasting during Ramadan Attenuates Proinflammatory Cytokines and Immune Cells in Healthy Subjects. The 1st Annual Meeting of the Middle-Eastern Association for Cancer Research (MEACR 2011). Tanta University, Egypt, 27-28, 12, 2011. 12. Potential in vitro and in vivo antitumor effects of polyphenolic compounds on experimental tumor ascites. The 1st Annual Meeting of the Middle-Eastern Association for Cancer Research (MEACR 2011). Tanta University, Egypt, 27-28, 12, 2011. 13. Brief in vitro triggering of toll-like receptor signaling in fresh bone marrow cells induces acquisition of dendritic cell-like phenotype and effective antigen presentation capability. The 1st Annual Meeting of the Middle-Eastern Association for Cancer Research (MEACR 2011). Tanta University, Egypt, 27-28, 12, 2011. 14. Genetic engineering of poorly immunogenic cancer cells with a xenogenic antigen increases their responses to chemotherapy and formation of anti-tumor immunity. The 1st Annual Meeting of the Middle-Eastern Association for Cancer Research (MEACR 2011). Tanta University, Egypt, 27-28, 12, 2011. 15. Enhancing Undergraduate Student Learning by Research-based Teaching. The 1st International conference on Education Development. Organized by The 5th Meeting of Egyptian Association Abroad for Enhancement and Development of Education in Egypt, Cairo University, Egypt, October 29-31, 2011. 16. Self Experience in the Use of Adoptive T Cell Transfer in Anti-cancer Therapy. The Egyptian- German Society of Zoology, Bani Sweif University, Bani Sweif, Egypt, February, 2011. 17. Potential use of adoptive transfer of immune cells in anti-cancer therapy. The 37th annual conference for the Association of Egyptian American Scholars (AEAS). Role of Information
  31. 31. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 31 Technology and its Scientific Applications for Egypt's Advancement in the 21st Century, Cairo and Zagazig Universities, Cairo and Zagazig Cities, Egypt, Dec. 27-29, 2010. 18. The potential use of cell-based immunotherapy for treatment of cancer. The 36th annual conference for the Association of Egyptian American Scholars (AEAS). Cairo University, Egypt, Dec. 28-29, 2009. 19. Chemotherapy: Friend or foe for cancer Immunotherapy. The 5th International Conference on Biological Sciences (ICBS), Tanta University, Tanta, Egypt, November 5-6, 2008. 20. Fostering the roles of universities in implementing the sustainable development of the surrounding community. The 2nd Int. Environment Forum: New Environmental Horizons of Sustainable Environment. Tanta University, Egypt, 27-29 November, 2008. 21. Teaching versus research in academia: a symbiotic, mutual, or parasitic relationship. The 35th annual conference for the Association of Egyptian American Scholars (AEAS). Cairo University, Egypt, Dec. 27 - Dec. 29, 2008. 22. Fostering Research in the Research Institutes in Egypt: Establishing Institutional Regulation committees are a Must. The 35th annual conference for the Association of Egyptian American Scholars (AEAS). Cairo University, Egypt, Dec. 27 - Dec. 29, 2008. 23. Plenary talk: Chemotherapy: Friend or foe for cancer Immunotherapy. The 5th International Conferences on Biological Sciences (ICBS), Tanta University, Tanta, Egypt, November 5-6, 2008. 24. Cyclophosphamide treatment induces bone marrow to yield high numbers of functional dendritic cells with superior activation in vitro in response to the stimulatory effects of toll-like receptor ligands. The 5th International Conference on Biological Sciences (ICBS), Tanta University, Tanta, Egypt, November 5-6, 2008. 25. Impact of vaccination with poly-N-acetyl glucosamine gel (F2 gel) matrix loaded with soluble worm antigen preparation and interleukin-12 on Schistosoma mansoni infection. The 5th International Conference on Biological Sciences (ICBS), Tanta University, Tanta, Egypt, November 5-6, 2008. 26. Impact of chemotherapy on the efficacy of adoptive immunotherapy. The 5th International Conference on Biological Sciences (ICBS), Tanta University, Tanta, Egypt, November 5-6, 2008. 27. Faculty Research Development Project (FRDP) to support life sciences in Egypt. Annual American-Egyptian Association Scholars (AEAS) conference, National research Center, Cairo, Egypt, Dec. 25-27, 2006 28. Increase of the bacteriostatic function against early infection of mice with Listeria monocytogenes after treatment with beta-estradiol. Annual Conference of the Egyptian- German Society of Zoology, Sinai, Egypt, Feb. 1997. 1. Immunotoxicity of cadmium chloride in mice. Annual Conference of the Union Arab of Biologists, South Valley University, Egypt, Nov. 1996.
  32. 32. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 32 BIBLIOGRPAHY Original Articles *, Corresponding authors Manuscripts In Preparation /submitted 1. Kristina Andrijauskaite, Mohamed L. Salem, Samantha Suriano, Colleen Cloud, Mingli Li, Kelly Moxley, Gina Scurti, Elizabeth Garrett-Meyer, Shikhar Mehrotra, David Cole, Mark Rubinstein. IL-12-conditioning improves the transduction efficiency of CD8+ T cells. 2. *Mohamed L. Salem, Mark Rubenstein and David J. Cole: The toll-like receptor 3 agonist polyinosinic-cytidylic acid (poly(I:C) targets natural killer cells with NK1.1+CD11b+CD11c+B220+Ly6G- phenotype. Submitted, Nov. 2014. 3. Enas A El-Zamarany, Nahla E El-Ashmawy, Mohamed L Salem, Hoda A El-Bahrawy, Ghada MZ Al- Ashmawy. Dexamethasone modulates cultured monocyte-derived dendritic cells differentiation. Submitted, 2014. 4. Mohamed L. Salem, Mohamed Nassef, Soha Gomaa, Said Hammad, Rania Ibrahim. Modulation of the anti-tumor effects of adoptively transferred T cells with chemotherapy by co- administration of bone marrow cells. Submitted, 2014. 5. *Mohamed L. Salem, Shaimaa Talat, and Ahmed El-Barbary. Immunomodulatory and anti-tumor effects of single versus combinatorial treatment with cisplatin and cyclophosphamide in a mouse model of Ehrlich carcinoma. Submitted, 2014. 6. *Mohamed L. Salem, Abdel-Aziz A. Zidan, Abdel Raouf Abou Al-Azm, Hasan Albate, Maha Aldemelaawy, Mohamed Attia, Mohamed Abo Senna: High numbers of myeloid-derived suppressor cells associates with low levels of dendritic and T cells in Egyptian patients with chronic HCV infection who failed IFN-α therapy. Submitted, 2014. Manuscripts Published 7. Mark P. Rubinstein*, Ee Wern Su, Samantha Suriano, Colleen A. Cloud, Kristina M. Schwartz, Katelyn Williams, C. Bryce Johnson, Mingli Li, Gina M. Scurti, Mohamed L. Salem, Chrystal M. Paulos, Shikhar Mehrotra, Elizabeth Garrett-Mayer, Michael I. Nishimura, and David J. Cole. IL-12 enhances the function and anti-tumor activity in murine and human CD8+ T cells. In Press, Cancer Immunology and Immunotherapy. IP 3.701 8. Ahmed M. Ismail, Said M. Abdou, Hassan Abdel Aty, Adel H.Kamhawy, Mohammed Elhinedy, Mohammed Elwageh, Atef Taha, Amal Ezzat, Hoda A. Salem, Said Youssif, Mohamed L. Salem: Autologous transplantation of CD34+ bone marrow derived mononuclear cells in management of non-reconstructable critical lower limb ischemia. In Press Cytotechnology, Nov. 2014. IP 1.207 9. Mohamed Basyony, Mohamed L. Salem, Afaf M.El Atrash, Asmaa A. Salama: Immune- Potentiating and Chemopreventive Effects of White button Mushroom Extract in Ehrlich Ascites Carcinoma Bearing Swiss Albino Mice. Egyp. J Zoology, In Press, 2014. 10. *Mohamed L. Salem, Zeinab Attia, and Sohaila Galal: Acute inflammation induces immunomodulatory effects on myeloid cells associated with anti-tumor responses in a tumor mouse model. Submitted, Inflammation Research, 2014. IP 2.109 11. *Mohamed L Salem, Shoukry NM, Zidan AA, Vournakis J. Immunomodulatory effects of IL-12 released from poly-N-acetyl glucosamine gel matrix during schistosomiasis infection. Cytotechnology. 2014, 66(4):667-75. . IP 1.207 12. Díaz-Montero CM, Zidan AA, Pallin MF, Anagnostopoulos V, Mohamed L Salem, Wieder E,
  33. 33. Curriculum Vitae Mohamed Labib Salem, PhD July, 2014 33 Komanduri K, Montero AJ, Lichtenheld MG. Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: role of CD62L. Immunol Res. 2013, 57(1-3):23-33. IP 3.026 13. Mark P Rubinstein, Mohamed L Salem, Andrew L Doedens, Caitlin J Moore, Cody Chiuzan, Guillermo L Rivell, David J Cole and Ananda W Goldrath. G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses. J Hematology & Oncology 2013, 6:75. IP 2.475 14. Mo'ez Al-Islam E Faris, Safia Kacimi, Ref’at A Al-Kurd, Mohamed L. Salem, Yasser K Bustanji, Mohammad Mohammad: Intermittent Fasting during Ramadan Attenuates Proinflammatory Cytokines and Immune Cells in Healthy Subjects. Nutrition Research, 2012 Dec;32(12):947 IP 1.974 15. Abdel Raouf Abou El-Azm, Hassan El-Bate, Lobna Abou-Ali, Nagwa Mansour, Hussin Ghoraba and *Mohamed L. Salem. Correlation of the viral load with bone marrow changes and hematological abnormalities in pale patients with chronic hepatitis C virus. Archive Virology, 2012 Aug;157(8):1579-86. IP 2.111 16. *Mohamed L. Salem, Amir A. Al-Khami, Sabry A. El-Nagaar, Abdel-Aziz A. Zidan, Ismail M. Al-Sharkawi, C. Marcela Díaz-Montero, David J. Cole: Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide. Cellular Immunology. 2012, 376(1-2): 67-74. IP 1.974 17. Mark P. Rubinstein, Colleen Cloud, Tracy Vandenberg, Caitlin J. Moore, Kristina M. Schwartz, C. Bryce Johnson, David H. Craig, Mohamed L Salem, Chrystal M. Paulos, David J. Cole: Ex vivo IL- 12-priming during CD8+ T cell activation dramatically improves adoptive T cell transfer anti- tumor efficacy in a lymphodepleted host. J Am Coll Surg. 2012 Apr;214(4):700-7; discussion 707- 8. Epub 2012 Feb 22. IP 4.549 18. Faris Q Alenzi, Fawwaz A. Alenazi, Yehia Al-Kaabi, and *Mohamed L Salem: The use of growth factors to modulate the activities of antigen-specific CD8+ T cells in vitro. J Med Life. 2011 Nov 14;4(4):399-406. Epub 2011 Nov 24. Mohamed L Salem L. Salem, David Cole, Alberto J Montero. Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory. Am J Cancer Res. 2011 August 30; 1(7): 882–896. IP 19. *Mohamed L Salem, Faris Q. Alenzi. Thymoquinone, the active ingredient of Nigella sativa seeds, enhanced survival and activities of the antigen-specific CD8 T cells in vitro. British J Biomedical Sciences, 2011;68(3):131-137. IP 0.923 20. Faris QB Alenzi, Mahmoud Lotfy, Wasam Nasif, Mohamed El-Shahat, Mohamed Alenazi, Fawwaz A Alenazi, Waleed G Tamimi, Hasan Abusini, Mohamed L Salem: Biomedical research in the middle eastern countries: Update and insight using scimago Journal Rank Indicator. J Ayub Med Coll Abbottabad 2010;22(3): 100-5. 21. Faris Q. Alenzi, Mohamed L. Salem, Waleed G. Tamimi, Mahmoud Lotfy, Ali A. Aljabri, Saad S. Al-ghamdi, Laila Damanhouri, Talat Bukhari and Richard K.H.Wyse. NKH477 inhibits proliferatiofn and induces apoptosis in a panel of cancer cell lines. J. Postgraduate Medical Institute (JPMI), 2010: 24(3):182-187. IP 1.263 22. Faris Alenzi, Yousry E. Al-Bolkiny, Mohamed L. Salem: Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anti-cancer drug. Br J Biomed. Sci. 2010;67(1):20- 8. IP 0.923 23. * Mohamed L Salem, Wael Attia, Yousry E. Al-Bolkiny, Ismail M. Al-Sharkawi, Marina Demcheva,

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