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  1. 1. Problem    “One  in  three  pa+ents  having  surgery  in  some  se3ngs   with  limited  resources  become  infected.”       -­‐  World  Health  Organiza8on  • Many  district-­‐level  hospitals  and  private  clinics  (medium  size  facili8es)  in  Nepal  use          disinfec)on  measures,  like  flaming  or  concentrated  “barbicide,”  which  kill  some  but  not  all        microbes  on  their  medical  instruments.  • Steriliza)on  via  an  autoclave  kills  all  microbes  making  tools  safe  for  surgical  use,  but  is  not              commonly  prac8ced  due  to  a  lack  of  resources  and  training.  • Improper  steriliza8on  has  been  iden8fied  as  a  key  contributor  to  a  much  greater  incidence            of  infec8on  in  developing  vs.  developed  na8ons1,2,3    
  2. 2. Solu8on    Provide  Simple  and  Effec8ve  Steriliza8on  at  Low-­‐Cost   Our  product…   •  Can  be  powered  by  any  locally   available  energy  source   (kerosene  in  Nepal,  coal  stoves  in   Sierra  Leone),  not  just  electricity   like  most  other  autoclaves.   •  Is  small  efficient  and  portable   and  is  suitable  for  smaller  loads   of  district  level  hospitals  and   private  clinics,  unlike  the   oversized  compe88on.   •  Our  product  has  an  LED  interface   which  no8fies  the  user  when  the   steriliza8on  is  complete,  while   other  autoclaves  do  not   •  Our  product’s  price  range  is   much  more  appropriate  for  our   target  audience  
  3. 3. Innova8on   •  Low  cost  plaWorm  based  on   widely-­‐available  pressure   cookers   •  Easy  for  unskilled  users  to   operate  the  straighWorward   LED  display   •  Easily  to  calibrate  at  varying   eleva8ons  (very  important  at   high  eleva8on  in  Nepal)  
  4. 4. Nepali  Community   Tier  2   Tier  3  •  Health  posts  in  Nepal  have  8er  systems   ranging  from  1  to  4.  Our  target  audience   are  hospitals  in  8ers  2  and  3.  The  pa8ents   and  healthcare  workers  at  these   loca8ons  can  benefit  most  from  our   product.  •  We  are  partnering  with  the  doctors  in   •  We  will  make  mul8ple  trips  to  all  of  these   hospitals  in  the  five  loca8ons  on  the   loca8ons  in  Nepal  over  the  summer  of   right.       2011    
  5. 5. 12  Month  Projec8on    Income   Q1   Q2   Q3   Q4  Revenue   $15,300     $42,500     $51,000     $51,000    COGS   $10,800     $30,000     $36,000     $36,000    Gross  Profit   $4,500     $12,500     $15,000     $15,000    Profit  Margin   42%   42%   42%   42%                  Expense          Equipment   $5,080     $0     $0     $0    administra8ve   $420     $420     $420     $420    shipping   $900     $2,500     $3,000     $3,000    salaries   $480     $960     $1,080     $1,080    insurance   $0     $0     $0     $0    taxes   $1,125     $3,125     $3,750     $3,750            Total  Expense   $8,005     $7,005     $8,250     $8,250            Net  Income   ($3,505)   $5,495     $6,750     $6,750    workers   2   3   3   3  units  sold   90   250   300   300  
  6. 6. Team  LCAAS  (Low-­‐Cost  Advanced  Autoclave  Solu8on)  We  have  assembled  a  team  that  has  the  necessary  background  to  implement  this  undertaking  •  Greg  Tao  -­‐  Team  and  Technical  Lead  •  Hallie  Cho  -­‐  Business  Strategy  and  Development,  Design  consult,  Web  Designer  •  Hai  Tran  -­‐  Business  Development  •  Yida  Gao  -­‐  Business  Development,  Patent  Research  •  Shambhu  –  Nepali  Implementa8on  Co-­‐Director  •  Pramod  Krandel  –  Nepali  Implementa8on  Co-­‐Director  •  Nimesh  Ghimire  –  Nepali  Organiza8onal  Support  •  Dr.  Ishwar  Bhalarai  –  Medical  director  in  Nepal,  Clinical  Study  Designer    •  Dr.  John  Daniel  Kelly  –  Medical  consultant  
  7. 7. References  1.  Allegranzi  B  et  al.  Burden  of  endemic  health-­‐care-­‐ associated  infec8on  in  developing  countries:  systema8c   review  and  meta-­‐analysis.  The  Lancet  2011;  377:  228-­‐241.  2.  Eriksen  HM,  Chugulu  S,  Kondo  S,  Lingaas  E.  Surgical-­‐site   infec8ons  at  Kilimanjaro  Chris8an  Medical  Center.  J  Hosp   Infect  2003;  55:14-­‐20.  3.  Fehr  J,  Hatz  C,  Soka  I,  et  al.  Risk  factors  for  surgical  site   infec8on  in  a  Tanzanian  district  hospital:  a  challenge  for   the  tradi8onal  na8onal  nosocomial  infec8ons  surveillance   system  index.  Infect  Control  Hosp  Epidemiol  2006;  27:   1401–04.  4.  Centers  for  Disease  Control,  Guidelines  for  Disinfec8on   and  Steriliza8on  in  Healthcare  Facili8es  2008.