Problem “One in three pa+ents having surgery in some se3ngs with limited resources become infected.” -‐ World Health Organiza8on • Many district-‐level hospitals and private clinics (medium size facili8es) in Nepal use disinfec)on measures, like ﬂaming or concentrated “barbicide,” which kill some but not all microbes on their medical instruments. • Steriliza)on via an autoclave kills all microbes making tools safe for surgical use, but is not commonly prac8ced due to a lack of resources and training. • Improper steriliza8on has been iden8ﬁed as a key contributor to a much greater incidence of infec8on in developing vs. developed na8ons1,2,3
Solu8on Provide Simple and Eﬀec8ve Steriliza8on at Low-‐Cost Our product… • Can be powered by any locally available energy source (kerosene in Nepal, coal stoves in Sierra Leone), not just electricity like most other autoclaves. • Is small eﬃcient and portable and is suitable for smaller loads of district level hospitals and private clinics, unlike the oversized compe88on. • Our product has an LED interface which no8ﬁes the user when the steriliza8on is complete, while other autoclaves do not • Our product’s price range is much more appropriate for our target audience
Innova8on • Low cost plaWorm based on widely-‐available pressure cookers • Easy for unskilled users to operate the straighWorward LED display • Easily to calibrate at varying eleva8ons (very important at high eleva8on in Nepal)
Nepali Community Tier 2 Tier 3 • Health posts in Nepal have 8er systems ranging from 1 to 4. Our target audience are hospitals in 8ers 2 and 3. The pa8ents and healthcare workers at these loca8ons can beneﬁt most from our product. • We are partnering with the doctors in • We will make mul8ple trips to all of these hospitals in the ﬁve loca8ons on the loca8ons in Nepal over the summer of right. 2011
Team LCAAS (Low-‐Cost Advanced Autoclave Solu8on) We have assembled a team that has the necessary background to implement this undertaking • Greg Tao -‐ Team and Technical Lead • Hallie Cho -‐ Business Strategy and Development, Design consult, Web Designer • Hai Tran -‐ Business Development • Yida Gao -‐ Business Development, Patent Research • Shambhu – Nepali Implementa8on Co-‐Director • Pramod Krandel – Nepali Implementa8on Co-‐Director • Nimesh Ghimire – Nepali Organiza8onal Support • Dr. Ishwar Bhalarai – Medical director in Nepal, Clinical Study Designer • Dr. John Daniel Kelly – Medical consultant
References 1. Allegranzi B et al. Burden of endemic health-‐care-‐ associated infec8on in developing countries: systema8c review and meta-‐analysis. The Lancet 2011; 377: 228-‐241. 2. Eriksen HM, Chugulu S, Kondo S, Lingaas E. Surgical-‐site infec8ons at Kilimanjaro Chris8an Medical Center. J Hosp Infect 2003; 55:14-‐20. 3. Fehr J, Hatz C, Soka I, et al. Risk factors for surgical site infec8on in a Tanzanian district hospital: a challenge for the tradi8onal na8onal nosocomial infec8ons surveillance system index. Infect Control Hosp Epidemiol 2006; 27: 1401–04. 4. Centers for Disease Control, Guidelines for Disinfec8on and Steriliza8on in Healthcare Facili8es 2008.